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Found 109 clinical trials
Efficacy of Ibuprofen Chronotherapy in Healing After Surgical Extraction of the Mandibular Third Molar

Clinical and preclinical studies have demonstrated encouraging results of non-steroidal anti-inflammatory drug (NSAID) chronotherapy in the management and treatment of inflammatory diseases such as rheumatoid arthritis. However, no previous clinical trials have addressed how the timing of NSAID administration within the day affects pain and healing outcomes after oral surgery …

ibuprofen
NSAID
Accepts healthy volunteers
  • 14 views
  • 12 Feb, 2022
  • 1 location
Effect of Biophysical Stimulation on Intraspongious Bone Edema in Anterior Cruciate Ligament Reconstruction

The following study has as main objective to evaluate whether the use of I-ONE® therapy can reduce post-operative pain thanks to the modulation of inflammation in patients with bone bruise on the knee after anterior cruciate ligament (ACL) injury if applied 15 days before and 60 days after ACL reconstruction …

postoperative pain
ligament reconstruction
pain relieving
edema
anterior cruciate ligament reconstruction
  • 0 views
  • 19 Apr, 2022
  • 1 location
Is Reduced Hypoxia Through a Robot Intervention Associated With Sensory and Emotional Descriptions of Dyspnea Anxiety Depression Symptom Burden and Anxiolytics

Chronic Obstructive Pulmonary Disease (COPD) is associated with high morbidity and mortality. The Danish Lung Association estimates that 320,000 Danes live with COPD, of which approximately 50,000 with severe COPD. In 2017, records showed that 23,979 admissions in Denmark were related to COPD; of these patients, about 20% were readmitted …

pneumonia
dyspnea
oximetry
anxiolytics
depressed mood
  • 0 views
  • 24 Jan, 2021
  • 5 locations
Automated Oxygen Administration -Rethinking Interventions Alleviating Dyspnea in Patients With COPD

Chronic Obstructive Pulmonary Disease (COPD) is associated with high morbidity and mortality. The Danish Lung Association estimates that 320,000 Danes live with COPD, of which approximately 50,000 with severe COPD. In 2017, records showed that 23,979 admissions in Denmark were related to COPD; of these patients, about 20% were readmitted …

pneumonia
dyspnea
oximetry
anxiolytics
depressed mood
  • 0 views
  • 05 Mar, 2022
  • 5 locations
Effect of Montelukast Versus Co Enzyme in Sepsis

Sepsis is a leading cause of morbidity and mortality in intensive care units. Sepsis is a life-threatening organ dysfunction linked to a dysregulated host response to infection. It leads to overwhelming of systemic inflammation causing release of proinflammatory cytokines, which trigger overproduction of reactive oxygen species. Several animal studies with …

cytokines
dysregulated host response
resuscitation
antioxidants
antibiotics
  • 0 views
  • 10 Apr, 2022
Precision Medicine for Sng/Pain Control

Patients have different response to different treatment modalities, and sore/pain medicine is no exception. In our experience, low-level laser (LLL), ultrasound, and prolotherapy can reduce sore /pain through different genetic pathway. Whether the therapeutic effect is controlled by the genetic variants of those sore /pain related genes or not, is …

  • 0 views
  • 22 Dec, 2021
  • 1 location
Increased Emotional-motivational Processing in Patients With Chronic Pain and Its Neural Correlates

Chronic pain causes immense suffering and reductions in quality of life as well as enormous socioeconomic costs. Very many chronic pain patients fall into the category of unspecific pain, i.e. pain without clear medical explanation, with lacking effective treatments. It is assumed that a negative hedonic shift, characterized by excessive …

Accepts healthy volunteers
  • 0 views
  • 26 Apr, 2022
  • 1 location
EMG Biofeedback Treatment for Chronic Low Back Pain, Cancer Pain and Migraines (BEAT-Pain)

The purpose of this pilot efficacy study is to examine the effects of EMG-biofeedback (EMG-BF) on pain-related outcomes in Chronic Low Back Pain (CLBP) patients, Recent mastectomy and lumpectomy patients, and patients with episodic migraine. EMG-BF facilitates neuromuscular retraining and muscle relaxation by using audio and visual stimuli using an …

  • 10 views
  • 03 May, 2022
  • 1 location
Profile of Adherence to Therapy and Interventions to Promote Adherence in MS

Adherence is an active process wherein the patient acts in collaboration with the medical and paramedical staff in order to improve his/her health. Adherence to medication comprises of implementation and persistence and it is estimated to be around 50% in various chronic illnesses, including Multiple Sclerosis (MS). MS patients who …

nervous
disease or disorder
chronic disease
  • 7 views
  • 09 Apr, 2022
  • 1 location
Correlation of Lung Ultrasonography With Chest CT Findings in Cancer Patients With COVID-19 Viral Pneumonia

-10, G-CSF, MCP-1, MIP-1α and TNF) causes the development of cytokine release syndrome (CRS) which is considered as pathologic underpinning for disease progression and lead to severe collateral tissue

  • 0 views
  • 01 May, 2022