Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 105 clinical trials
Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH) and Other Histiocytic Disorders

This is a research study of a drug called cobimetinib in children and adults diagnosed with Langerhans cell histiocytosis (LCH), and other histiocytic disorders that has returned or does not respond to treatment. Cobimetinib blocks activation of a protein called Mitogen-activated protein kinase (MEK) that is part of incorrect growth …

  • 0 views
  • 11 Sep, 2021
  • 2 locations
Marine Algae Supplement and the Effects on Post Exercise Inflammatory Response

Fucoidans are fucose-rich sulfated carbohydrates found in brown marine algae and have been shown to play a role in immune modulation as well as inflammation. In fact, fucoidans have been shown to inhibit neutrophil infiltration and attenuate levels of pro-inflammatory cytokines. More research is warranted to determine the effects of …

Accepts healthy volunteers
  • 0 views
  • 18 Jan, 2022
  • 1 location
tSCI Contrast Enhanced Ultrasound Study

Patients with traumatic spinal cord injury (tSCI) often suffer from spinal cord swelling inside the thecal sac, which contains the spinal cord and surrounding fluid, leading to increased pressure on the spinal cord tissue and decreased spinal cord blood flow at the site of injury. The combination of increased pressure …

  • 6 views
  • 23 Jan, 2021
  • 1 location
Prediction of Recovery in Patients With Neck Pain

This prognostic prediction model will be a reference for the health care professionals in clinical decision making and subsequent outcomes in dealing with patients having sub-acute and chronic neck pain, as well as, it will be a guide regarding therapeutic management and patients' education. Although various studies have evaluated the …

neck pain
  • 0 views
  • 12 Aug, 2021
  • 1 location
Elotuzumab in Immunoglobulin G4-Related Disease (IgG4-RD)

This is a two-part multi-center clinical trial in participants with active IgG4-RD. Part 1 (Cohort 1a and Cohort 1B) is an open-label, dose escalation phase to determine the safety of elotuzumab for investigation in IgG4-RD. Part 2 (Cohort 2) is a randomized, placebo-controlled, double-blinded (masked) trial phase to compare the …

  • 0 views
  • 21 Oct, 2021
  • 1 location
The Validity of the Quick Renal MRI in Pediatric Kidney Disease

The investigators propose a new imaging method for children born with congenital anomalies of the urinary tract that is a rapid, injection-, sedation-, and radiation-free alternative: the quick renal MRI. This proposal hypothesizes that the quick renal MRI has high validity compared to current radiologic standard for renal infection and …

  • 6 views
  • 18 Nov, 2021
  • 1 location
Whole Breast + Lymph Node Irradiation: Prone Compared to Supine Position in 15 or 5 Fractions

The goal of this trial is to evaluate the effect of the prone crawl treatment position and/or accelerated schedule on acute and late toxicities, as well as quality of life and time management for breast cancer patients receiving whole breast and regional nodal irradiation after breast conserving surgery.

breast cancer
immunostimulant
cancer
breast-conserving surgery
  • 10 views
  • 22 Jan, 2021
  • 1 location
A Study to Evaluate Renal Fibrosis Using MRI Techniques

The purpose of this study is to evaluate whether or not an MRI technique (quantitative magnetization transfer or qMT) in narrowing human kidneys is feasible, reproducible, and predicts recovery.

antihypertensive drugs
hypertension
angiography
  • 0 views
  • 29 Oct, 2021
  • 1 location
The Effect of Massage in Preventing Pressure Wound Development

Pressure Wound (PW) is a chronic wound that develops in soft tissue as a result of the capillary end pressure which rising above 32 mmHg. It is the most common complication with 31% annual incidence after spinal cord injuries. Pressure wound is considered as malpractice for nursing practices. It decreases …

Accepts healthy volunteers
  • 0 views
  • 02 Dec, 2021
  • 1 location
The Preterm Infants' Paracetamol Study

Present randomized, controlled, double-blind trial investigates the efficacy and safety of early (<24 h) intravenous paracetamol therapy for pain medication in very small premature infants. This phase 2 drug study focuses on the efficacy and safety of short-term use. The pharmacokinetics and pharmacodynamics of paracetamol, as well as the long-term …

  • 0 views
  • 26 Jan, 2021
  • 1 location