Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
I am looking for
added new label for I am looking for
Advanced Filters
Found 32 clinical trials
Hyponatremia Study (Delayed Hyponatremia After Pituitary Surgery) (DHAPS)

Hyponatremia is defined as sodium below the normal range of 135-145. Symptomatically, it can cause patients to experience a wide range of symptoms including lethargy, headache, nausea, vomiting and in severe cases coma and even death. The goal of this study is to prospectively compare two approaches to the postoperative …

fluid restriction
growth hormone
  • 20 Apr, 2022
  • 1 location
Inducing a Hypothyroxinemic State in Patients With Recurrent Glioblastoma or Gliosarcoma

This early phase I trial studies the safety and feasibility of inducing a hypothyroxinemic state in patients with glioblastoma or gliosarcoma that has come back (recurrent). This trial aims to see if giving a specific thyroid hormone, such as methimazole and liothyronine, is safe and could benefit cancer treatment.

  • 08 Mar, 2022
  • 1 location
The Gut Microbiome as an Indicator of Readiness for Head & Neck Cancer Surgery

The purpose of this study is to understand how a pre-operative nutritional intervention alters the gut microbiome and improves outcomes after major head and neck cancer surgery.

neck dissection
  • 06 Apr, 2023
  • 1 location
Four Doses of MAGE Vaccine for Patients With Squamous Cell Carcinoma of the Head and Neck

Squamous Cell Carcinoma of the Head and Neck (SCCHN) effects 43,000 individuals in the United States annually with an estimated overall survival of 50%. For some patients who develop local or distant metastases following primary therapy, surgery is not an option. This study is being done to test the safety …

squamous cell carcinoma
  • 07 Nov, 2020
  • 1 location
The Short-chain Fatty Acid Acetate for Improving Age-associated Arterial Dysfunction

Cardiovascular diseases are the leading cause of morbidity and mortality and contribute most to healthcare costs in the U.S. Age is the strongest cardiovascular disease risk factor, with >90% of all deaths from cardiovascular disease occurring in adults >50 years old. The age-associated increased risk of cardiovascular disease is due, …

Accepts healthy volunteers
  • 25 Oct, 2022
  • 1 location
Evaluate the Efficacy and Safety of Ruxolitinib on Hair Regrowth in Patients With Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy (APECED)-Associated Alopecia Areata

Background Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED) is a problem of the immune system. In people with APECED, the immune system makes a mistake and attacks the body. Some people with APECED have a type of hair loss called alopecia areata (AA). No drugs are approved to treat AA. Objective …

blood tests
areata alopecia
bilateral tubal ligation
graft-versus-host disease
  • 15 Aug, 2023
  • 1 location
The Impact of Dietary Pattern on Erectile Function (ERECTION)

The goal of this study is to determine whether erectile function is impacted by dietary patterns in healthy men with normal erectile function.

Accepts healthy volunteers
  • 20 Sep, 2023
Nicotinamide Riboside for Treating Elevated Systolic Blood Pressure and Arterial Stiffness in Middle-aged and Older Adults

Aging is the primary risk factor for cardiovascular diseases (CVD), the number one cause of death in developed societies. Systolic blood pressure (SBP) increase with age and is a key intermediary factor linking aging to increased CVD risk. The primary mechanisms underlying the age-associated increase in SBP is stiffening of …

caloric restriction
cholesterol level
systolic blood pressure
  • 24 Mar, 2022
  • 1 location
Oleanolic Acid as Therapeutic Adjuvant for Type 2 Diabetes Mellitus (OLTRAD STUDY) (OLTRAD)

Oleanolic acid (OA), is a natural component of many plant food and medicinal herbs, which has shown to exert in experimental models hypoglycemic and hypolipidemic effects, and also a cytoprotective action against oxidative and chemotoxic stress underlying Type II Diabetes Mellitus (T2DM).Today it is known that OA shares mechanisms of …

  • 18 Sep, 2023
  • 1 location
Inspiratory Muscle Strength Training for Lowering Blood Pressure and Improving Endothelial Function in Postmenopausal Women: Comparison With "Standard of Care" Aerobic Exercise

High blood pressure (BP) is the major modifiable risk factor for cardiovascular diseases (CVD) and related health conditions, particularly among postmenopausal (PM) women. In adults age ≥50 years this risk is primarily driven by above-normal systolic BP (SBP ≥120 mmHg), as diastolic BP plateaus, then decreases in older adulthood. Although …

systolic blood pressure
endothelial dysfunction
Accepts healthy volunteers
body mass index
  • 13 Jun, 2022
  • 1 location