Found 27 clinical trials
Antithymocyte Globulin as a Second Line Therapy in Graves Orbitopathy
The overall objective of the study is to evaluate the safety and efficacy of rabbit antithymocyte globulin in the treatment of Graves orbitopathy (GO) after ineffective treatment with moderate-to-high doses of glucocorticoids.
- 0 views
- 25 Mar, 2022
Phase I Study of AZD5363 + Olaparib + Durvalumab in Patients With Advanced or Metastatic Solid Tumor Malignancies
This is a Phase 1 dose-escalation study to evaluate the safety and tolerability of combination treatment of AZD5363 + Olaparib + Durvalumab and to determine the RP2D in patients with advanced or metastatic solid tumor malignancies. The purpose of this trial is to determine if combination treatment of drugs, Olaparib, …
- 0 views
- 22 Jan, 2021
- 1 location
Gastrografin for Treating Small Bowel Obstruction in Children
This is a multi-centre clustered open label clinical trial testing the effectiveness of adding Gastrografin to standard non-surgical management of small bowel obstruction. Gastrografin is a radiopaque contract agent that exhibits a mild laxative effective due to its high osmolarity and ability to pull water into the intestines and bowels …
- 15 views
- 22 Apr, 2022
- 1 location
Study on Vascular Function, Sarcopenia and Pain in Treated Postmenopausal Osteoporosis (VASCO)
This study aims to follow a cohort of osteoporotic patients treated with anti-osteoporotic drugs and to evaluate the impact of these treatments on the osteoporosis-cardiovascular-sarcopenia triad and on pain.
- 0 views
- 24 Oct, 2022
- 1 location
MAGnesium Effect With ANtiosteoporotic Drugs (MAGELLAN)
Randomized pilot clinical trial to demonstrate superiority of bisphosphonate-magnesium combination over bisphosphonates alone in postmenopausal osteoporosis in slowing bone remodeling as assessed by C-terminal telopeptide of bone collagen type 1 (CTX) dosage.
- 0 views
- 08 Jul, 2022
- 1 location
The Importance of Iodine During Pregnancy for Future Brain Function : a Randomized Placebo-controlled Trial. Swedish Iodine in Pregnancy and Development in Children (SWIDDICH) Study (SWIDDICH)
THE ULTIMATE GOAL of this project is to answer the question "In MILD IODINE DEFICIENCY (ID), should a tablet with vitamins and minerals, including 150 μg iodine/day be administered to pregnant women with a normal diet, to attain a normal cognitive development of the fetus or is there no cognitive …
- 12 views
- 23 Oct, 2022
- 2 locations
The Use of 124-I-PET/CT Whole Body and Lesional Dosimetry in Differentiated Thyroid Cancer
Study rationale High risk patients with differentiated thyroid cancer (DTC) require therapy with 131 I under thyroid stimulating hormone (TSH) stimulation. There are two methods of TSH
- 13 views
- 06 Apr, 2023
- 1 location
The Impact of a Powdered Meal Replacement on Metabolism and Gut Microbiota (PREMIUM)
, adiponectin, leptin, free glycerol, free fatty acids, and thyroid stimulating hormone) Resting energy expenditure; Body composition; Appetite sensations (hunger, satiety, fullness
- 22 views
- 04 Oct, 2022
- 1 location
Glutathione in Mild Cognitive Impairment
Elderly humans have an increased risk of dementia which begins as mild defects in memory called mild cognitive impairment. Glutathione (GSH), a key endogenous antioxidant has been linked to cognition. This exploratory study will investigate mechanisms linked to GSH for cognitive impairment (and improvement) by studying humans with mild cognitive …
- 0 views
- 25 Mar, 2022
- 1 location
Hyponatremia Study (Delayed Hyponatremia After Pituitary Surgery) (DHAPS)
Hyponatremia is defined as sodium below the normal range of 135-145. Symptomatically, it can cause patients to experience a wide range of symptoms including lethargy, headache, nausea, vomiting and in severe cases coma and even death. The goal of this study is to prospectively compare two approaches to the postoperative …
- 262 views
- 20 Apr, 2022
- 1 location