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Found 6 clinical trials
Study of SO-C101 and SO-C101 in Combination With Pembro in Adult Patients With Advanced/Metastatic Solid Tumors

A multicenter open-label phase 1/1b study to evaluate the safety and preliminary efficacy of SO-C101 as monotherapy and in combination with pembrolizumab in patients with selected advanced/metastatic solid tumors

measurable disease
biological factors
cancer chemotherapy
solid tumors
serum pregnancy test
  • 30 Apr, 2022
  • 7 locations
PT-112 in Subjects With Thymoma and Thymic Carcinoma

Background There are no approved drugs to treat recurrent thymoma and thymic carcinoma. New therapies are needed for people with these cancers. Researchers want to see if the drug PT-112 can help. PT-112 kills cancer cells. It also helps the body s immune system fight cancer. Objective To see if …

  • 28 Jul, 2022
  • 1 location
Bintrafusp Alfa (M7824) in Subjects With Thymoma and Thymic Carcinoma

Background Thymoma and thymic carcinoma are diseases of the thymus. Platinum-based chemotherapy is the standard treatment for these diseases. But in many cases, the disease returns after treatment. Researchers want to see if a new drug can help. Objective To see if bintrafusp alfa (M7824) is an effective treatment for …

  • 04 Oct, 2022
  • 1 location
Prospective Exploratory Study of FAPi PET/CT With Histopathology Validation in Patients With Various Cancers (FAPI PET RDRC)

This exploratory study investigates how an imaging technique called 68Ga-FAPi-46 PET/CT can determine where and to which degree the FAPI tracer (68Ga-FAPi-46) accumulates in normal and cancer tissues in patients with cancer. Because some cancers take up 68Ga-FAPi-46 it can be seen with PET. FAP stands for Fibroblast Activation Protein. …

ct scan
pet scan
positron emission tomography
  • 23 Jul, 2022
  • 1 location
Integrated Cancer Repository for Cancer Research (iCaRe2)

The iCaRe2 is a multi-institutional resource created and maintained by the Fred & Pamela Buffett Cancer Center to collect and manage standardized, multi-dimensional, longitudinal data and biospecimens on consented adult cancer patients, high-risk individuals, and normal controls. The distinct characteristic of the iCaRe2 is its geographical coverage, with a significant …

Accepts healthy volunteers
primary cancer
early detection
early diagnosis
  • 13 Mar, 2022
  • 61 locations
The Registry of Oncology Outcomes Associated With Testing and Treatment

This study is to collect and validate regulatory-grade real-world data (RWD) in oncology using the novel, Master Observational Trial construct. This data can be then used in real-world evidence (RWE) generation. It will also create reusable infrastructure to allow creation or affiliation with many additional RWD/RWE efforts both prospective and …

diagnostic procedures
lab tests
primary cancer
  • 22 Oct, 2021
  • 1 location