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Found 38 clinical trials
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Integrated Cancer Repository for Cancer Research

The iCaRe2 is a multi-institutional resource created and maintained by the Fred & Pamela Buffett Cancer Center to collect and manage standardized, multi-dimensional, longitudinal data and biospecimens on consented adult cancer patients, high-risk individuals, and normal controls. The distinct characteristic of the iCaRe2 is its geographical coverage, with a significant …

early detection
primary cancer
cancer
early diagnosis
  • 1321 views
  • 26 Jan, 2021
  • 86 locations
None
Evaluation of Cell Changes in Blood and Tissue in Cancers of the Lung Esophagus and Lung Lining

Background Chromatin is is the structural building block of a chromosome. It is found inside the nucleus of the cell and consists of a complex of DNA and protein. Cancers of the lung, pleura (lung lining) and esophagus show profound changes in chromatin structure that may affect the course of …

carcinoma
bronchoscopy
withdrawn
metastasis
lung carcinoma
  • 139 views
  • 08 Dec, 2021
  • 1 location
None
Natural History and Biospecimen Acquisition for Children and Adults With Rare Solid Tumors

Background Approximately 150 cases of cancer per one million per year are considered rare cancers. While all tumors originate from genetic changes, a small percentage of these tumors are familial. Researchers want to study these changes in biological samples from people with rare tumors in order to learn more about …

cns tumor
solid tumor
cancer
Accepts healthy volunteers
  • 0 views
  • 08 Dec, 2021
  • 1 location
None
Single Cell Sequencing Analysis of Thymoma

and protein expression in patients with malignant thymoma, compared to Benign thymoma, at a single-cell level using a flow cytometry and RNA-sequencing protocol.

thymic neoplasm
scrna
cancer
thymic carcinoma
  • 0 views
  • 14 Jun, 2021
  • 1 location
None
TheRapeutic Effect of Different immunosuppressAnts on Non-Thymoma Ocular Myasthenia Gravis: a Real-world Study

This study collects the clinical data of new-onset ocular myasthenia gravis (OMG) patients, assesses outcomes and adverse effects of different treatment options, and evaluate risk factors of conversion to generalized MG(GMG).

ocular myasthenia
pyridostigmine
single fiber emg
acetylcholine
immunosuppressive agents
  • 0 views
  • 23 Jan, 2021
  • 1 location
None
Rapid Autopsy and Procurement of Cancer Tissue

Background Individuals with cancer of the lung, chest cavity, ovary, or bladder, as well as patients who have been treated with adoptive cell therapy unfortunately commonly succumb to their disease. Some agree to donate their bodies to cancer research that may help the medical community better understand these diseases. Studies …

bladder cancer
thymic carcinoma
cancer
carcinoma
thymoma
  • 44 views
  • 12 Sep, 2021
  • 1 location
None
Immune Regulation in Patients With Common Variable Immunodeficiency and Related Syndromes

This study will explore the cause of immunodeficiency in common variable immunodeficiency (CVI) and other related immunodeficiency syndromes-IgA deficiency, hyper IgM syndrome, thymoma and

immunodeficiency
anti-inflammatory drugs
pulmonary function tests
agammaglobulinemia
hypogammaglobulinemia
  • 626 views
  • 16 Oct, 2021
  • 1 location
None
Lymphoma Patients Undergoing Mediastinal Radiotherapy in the Era of Modern Chemoradiation

Malignant anterior mediastinal tumors essentially include lymphomas and thymomas. The location of mediastinum is anatomically close to several critical organs such as heart, lung, and breasts

cancer
lymphoma
hodgkin's disease
  • 0 views
  • 21 Mar, 2021
  • 1 location