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Found 37 clinical trials
Randomized, Multicenter, Phase III Trial to Assess Conformal Post-operative Radiotherapy vs. Surveillance After Complete Resection of Stage II/III Thymoma (RADIO-RYTHMIC)

The primary objective of the study : to compare the Recurrence-Free survival (RFS) between arms. RFS is defined as time from randomisation to the first recurrence (either local-regional or distant) or death of any cause.

  • 0 views
  • 25 Mar, 2022
  • 2 locations
Nivolumab in Patients With Type B3 Thymoma and Thymic Carcinoma (NIVOTHYM) (NIVOTHYM)

The aim of the phase II Nivothym study is to collect data on activity and toxicity of nivolumab therapy in patients with thymic carcinoma or type B3 thymoma that previously received a first

gilbert's syndrome
platelet count
renal function
liver metastasis
serum pregnancy test
  • 183 views
  • 22 Jul, 2022
  • 14 locations
Study of SO-C101 and SO-C101 in Combination With Pembro in Adult Patients With Advanced/Metastatic Solid Tumors

A multicenter open-label phase 1/1b study to evaluate the safety and preliminary efficacy of SO-C101 as monotherapy and in combination with pembrolizumab in patients with selected advanced/metastatic solid tumors

cancer chemotherapy
serum pregnancy test
pembrolizumab
neuropathy
solid tumors
  • 43 views
  • 30 Apr, 2022
  • 7 locations
PT-112 in Subjects With Thymoma and Thymic Carcinoma

Background There are no approved drugs to treat recurrent thymoma and thymic carcinoma. New therapies are needed for people with these cancers. Researchers want to

  • 0 views
  • 28 Jul, 2022
  • 1 location
Bintrafusp Alfa (M7824) in Subjects With Thymoma and Thymic Carcinoma

Background Thymoma and thymic carcinoma are diseases of the thymus. Platinum-based chemotherapy is the standard treatment for these diseases. But in many cases

  • 27 views
  • 25 Jul, 2022
  • 1 location
Chemotherapy Combined With Pembrolizumab in Treating Patients With Thymoma and Thymic Carcinoma

This is an investigational, single arm study.

cancer
neutrophil count
serum pregnancy test
carcinoma
chemotherapy regimen
  • 0 views
  • 26 Jan, 2021
  • 1 location
Adjuvant Treatment for Incomplete Resection Thymoma or Thymic Carcinoma

This study is designed to investigate whether adjuvant radiochemotherapy after incomplete resection has a better survival than adjuvant radiotherapy for thymoma or thymic carcinoma.

thymic neoplasm
etoposide
renal function
carcinoma
thymic carcinoma
  • 68 views
  • 23 Jan, 2021
  • 1 location
A Pilot Study to Investigate the Safety and Clinical Activity of Avelumab (MSB0010718C) in Thymoma and Thymic Carcinoma After Progression on Platinum-Based Chemotherapy

Background Thymoma and thymic carcinoma are cancers originating in the thymus gland. Platinum-based chemotherapy is standard treatment for them. But not uncommonly

cancer
avelumab
neutrophil count
benadryl
pd-l1
  • 56 views
  • 12 Aug, 2022
  • 1 location
Pembrolizumab and Sunitinib Malate in Treating Participants With Refractory Metastatic or Unresectable Thymic Cancer

This phase II trial studies how well pembrolizumab and sunitinib malate work in treating participants with thymic cancer that has spread to other places in the body or cannot be removed by surgery and does not respond to treatment. Monoclonal antibodies, such as pembrolizumab, may interfere with the ability of …

liver metastasis
serum pregnancy test
carcinoma
chemotherapy regimen
thymic carcinoma
  • 7 views
  • 16 May, 2022
  • 1 location
KN046 (a Humanized PD-L1/CTLA4 Bispecific Single Domain Fc Fusion Protein Antibody) in Subjects With Thymic Carcinoma

This is a Phase 2, open-label, multi-center, single arm study in subjects with advanced thymic carcinoma after failure of platinum-based combination chemotherapy. Subjects should have documented

measurable disease
carcinoma
chemotherapy regimen
thymic carcinoma
progressive disease
  • 0 views
  • 25 May, 2022
  • 1 location