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Found 7 clinical trials
Pregnancy and Risk of Venous Thromboembolism

anti-thrombotic prophylaxis. This study will personalize care using a score to individually assess the risk and propose appropriate prevention. The main objective of this study is to conduct a

  • 0 views
  • 28 Jan, 2021
Rivaroxaban as Thrombosis Prophylaxis in Bariatric Surgery

The aim of this study is to investigate the efficacy and safety of rivaroxaban in obese patients undergoing bariatric surgery. The objectives are to assess the safety and feasibility of venous thromboembolism (VTE) prophylaxis and lung embolism with Rivaroxaban 10mg as an oral anticoagulant. After bariatric surgery patients receive the …

oral anticoagulants
rivaroxaban
rivaroxaban 10 mg
  • 6 views
  • 27 Jan, 2021
  • 3 locations
Deep Vein Thrombosis Prophylaxis Adherence: Enoxaparin vs Rivaroxaban

The objective of this study is to compare oral rivaroxaban with injectable enoxaparin in orthopaedic trauma patients to determine if orally administered rivaroxaban once daily carries greater compliance and overall satisfaction than enoxaparin self-administered by subcutaneous injection once daily.

thrombosis
venous thrombosis
thrombosis prophylaxis
enoxaparin
deep vein thrombosis
  • 5 views
  • 23 Jan, 2021
  • 1 location
Improved Adherence With Extended Venous Thromboembolism Prophylaxis After Major Cancer Surgery

adherence to extended deep vein thrombosis prophylaxis (DVT) with the direct oral anticoagulant apixaban on the background of historical data from the investigator's center on low-molecular-weight heparin

  • 0 views
  • 07 Mar, 2021
  • 2 locations
Silmitasertib (CX-4945) in Patients With Severe Coronavirus Disease 2019 (COVID-19)

This multi-center, open-label, 2 arm parallel-group, randomized, interventional prospective exploratory study in 40 patients aimed to evaluate safety and explore putative clinical benefits of Silmitasertib 1000 mg BID dose in patients with severe illness caused be SARS-COV-2. This will be a two-arm trial comparing the SOC/best supportive care alone to …

  • 0 views
  • 13 Apr, 2021
  • 2 locations
Vitamin C Hydrocortisone and Thiamine for Septic Shock

Prior data has shown that both corticosteroids and vitamin C reduce the activation of nuclear factor B (NFB), thereby ultimately attenuating the systemic inflammatory response to sepsis/septic shock and augmenting the responsiveness to vasopressors. Therefore, the current investigators hypothesized that the combined use of vitamin C and stress-dose hydrocortisone may …

sepsis
thiamine
procalcitonin
organ failure
vasoconstrictor
  • 9 views
  • 26 Jan, 2021
  • 2 locations
Vitamin C Steroids and Thiamine and Cerebral Autoregulation and Functional Outcome in Septic Shock

This study has been approved as a nested substudy of a multicenter trial (CORVICTES, Clinicaltrials.gov Identifier: NCT03592693). The current, randomized, placebo-controlled study will compare steroids/vitamin C versus placebo/placebo in septic shock, with respect to cerebral autoregulation, biomarkers, and functional outcome. The following hypotheses will be tested: The steroids/vitamin C/thiamine intervention …

thiamine
  • 10 views
  • 28 Jan, 2021
  • 1 location