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Found 23 clinical trials
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A multicenter clinical study of the Sonablate® 500 (Sonablate) for the TreAtment of locally Recurrent prostate cancer with HIFU(STAR Trial)

A multicenter clinical study of the Sonablate® 500 (Sonablate) for the TreAtment of locally Recurrent prostate cancer with HIFU(STAR Trial)

  • 196 views
  • 25 Mar, 2021
  • 1 location
A Study to Assess the Reversal of the Anticoagulant Effects of JNJ-70033093 by 4-Factor Prothrombin Complex Concentrate (4F-PCC) (Part 1) and Recombinant Human Factor VIIa (rFVIIa) (Part 2) in Healthy Participants

(rFVIIa) in healthy participants as measured by changes from baseline of the coagulation testing parameters (activated partial thromboplastin time [aPTT] and thrombin generation assay [TGA]).

  • 0 views
  • 05 Jun, 2021
  • 1 location
The Effect of a Levonorgestrel-releasing Intrauterine Device (IUD) Versus a Copper Containing IUD on Risk of Blood Clots

), factor VIIIc, activated partial thromboplastin time (aPTT) and activated partial thromboplastin time plus activated protein C (aPTT + APC). Both groups will undergo a GYN exam with screening

thrombosis
thrombin
copper
protein c
d-dimer
  • 131 views
  • 07 Nov, 2020
  • 1 location
Valproic Acid and Dihydroergotamine as Abortive Therapy in Pediatric Migraine

The objective of this study is to compare clinical efficacy and tolerability of valproic acid (VPA) therapy versus dihydroergotamine (DHE) as abortive therapy in pediatric migraine.

  • 0 views
  • 24 Jan, 2021
  • 1 location
Operative Procedures vs. Endovascular Neurosurgery for Untreated Pseudotumor Trial

Pseudotumor cerebri, also called idiopathic intracranial hypertension (IIH), is characterized by elevated intracranial pressure, headache, and if severe, vision loss. IIH is difficult to treat. Medical management may not adequately resolve the symptoms, and surgical management (primarily through cerebrospinal fluid [CSF] shunting) has a high failure rate. Recently, a relationship …

  • 0 views
  • 25 Jan, 2021
  • 1 location
Early Versus Late Post Caesarean Section Oral Anticoagulation Initiation and Risk of Maternal Complications in Patients With Mechanical Heart Valve Prosthesis

A randomized cohort study applied to patients with mechanical heart valve prosthesis who will be delivered by caesarean section at or after 28 weeks of gestation . Using a table of random numbers, participants will be divided into 2 equal groups. Group A (57 patients) in which warfarin will be …

  • 0 views
  • 29 Apr, 2021
  • 1 location
TheraSphere & Treatment of Unresectable Primary or Unresectable Secondary Liver Cancer

Protocol Synopsis Title A Humanitarian Device Exemption Use Protocol of TheraSphere For Treatment of Unresectable Primary or Secondary Liver Neoplasia Supplier BTG International Canada Inc. Type of Clinical Use Post-Marketing: TheraSphere commercially distributed under HDE # 980006 Objectives Provide supervised access to TheraSphere therapy at this institution Evaluate response to …

  • 0 views
  • 23 Jan, 2021
  • 1 location
Heparin Anticoagulation in Septic Shock

This study is a pragmatic open-label international randomized trial comparing therapeutic dose intravenous unfractionated heparin (UFH) to standard care venous thromboprophylaxis in patients diagnosed with septic shock.

arterial ph
norepinephrine
mechanical ventilation
dopamine
systolic blood pressure
  • 121 views
  • 04 Feb, 2021
  • 50 locations
To Assess the Pharmacokinetics and Safety and Tolerability of Efanesoctocog Alfa (BIVV001)in Adults With Type 2N and 3 Von Willebrand Disease (VWD)

-stage activated partial thromboplastin time (aPPT) clotting assay, as well as, BIVV001 capture chromogenic Coatest FVIII activity assay Secondary Objective: -To assess the safety and

ddavp
antihemophilic factor
bleeding tendency
coagulation factor
coagulation studies
  • 0 views
  • 09 Jul, 2021
  • 1 location
A Phase 3 Open-label Interventional Study of an Intravenous Recombinant Coagulation Factor VIII Fc-von Willebrand Factor-XTEN Fusion Protein Efanesoctocog Alfa (BIVV001) in Patients With Severe Hemophilia A

the 1-stage activated partial thromboplastin time (aPTT) and 2-stage chromogenic FVIII activity assays

cryoprecipitate
antihemophilic factor
treatment regimen
von willebrand's disease
coagulation factor
  • 13 views
  • 27 Feb, 2021
  • 3 locations