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Found 56 clinical trials
Role of Fcgamma Receptors in Immune Thrombocytopenia (ITP)

Immune thrombocytopenia (ITP) is an autoimmune disease characterized by a peripheral destruction of platelets responsible for bleedings. Monocytes/macrophages play a double role by phagocyting platelets recognized by autoantibodies and by maintaining the autoimmune response via their antigen-presenting cell functions. Fcgamma receptors (FcR), that are represented by activating receptors (FcRI, FcRIIa, …

arthritis
thrombocytopenia
autoimmune disease
autoimmune thrombocytopenia
lupus
  • 12 views
  • 01 Jul, 2021
  • 1 location
An Observational, Multicenter Study to Evaluate the Use and Effectiveness of Doptelet® in Patients With ITP (ADOPT)

This is a multi-center, observational, Phase 4 study in patients with Immune Thrombocytopenia (ITP) designed to describe the real-world effectiveness of Doptelet and assess the patterns of drug utilization to add to the knowledge base regarding the use of Doptelet in routine medical practice. Patients eligible for participation will, as …

avatrombopag
thrombocytopenia
  • 0 views
  • 16 Mar, 2022
  • 1 location
Biological Bank for the Patients Followed in a Constitutive Reference Center for Autoimmune Cytopenia (BIOCAI)

The Internal Medicine Department of Haut-Lévêque Hospital (Pr E LAZARO, Pr JL PELLEGRIN, Pr JF VIALLARD) was accredited in 2017 by the Ministry of Health as a Constitutive Reference Center for Autoimmune Cytopenia. The investigators wish to launch new research projects in autoimmune cytopenia and propose a translational and fundamental …

cytopenia
  • 3 views
  • 21 Mar, 2022
  • 1 location
Observational Study of Fostamatinib as Second Line Therapy in Adult Patients With Immune Thrombocytopenia (ITP) and Insufficient Response to a Prior Therapy

Evaluate patient characteristics, treatment patterns, clinical outcomes and safety of fostamatinib as second-line therapy in real-world clinical practice, for the treatment of ITP in adult patients who have an insufficient response to prior therapy (steroids immunoglobulins).

immunoglobulins
immune globulin
thrombocytopenia
fostamatinib
  • 0 views
  • 28 Jul, 2021
  • 8 locations
Biorepository and Registry for Plasma Exchange Patients

Patients who have immune mediated diseases commonly undergo plasma exchange (PLEX) procedures to remove pathological substances, typically believed to be antibodies. At our facility about 400 of these procedures are performed annually on 40-60 different patients. These procedures are considered within the standard of care for these patients and are …

plasma exchange
immune globulin
cell counts
  • 0 views
  • 22 Aug, 2021
  • 1 location
Severe Immune Cytopenia Registry Www.Sic-reg.Org (sic-reg)

Prospective registry study for children and young adults with severe immune cytopenias (persisting/chronic immune thrombocytopenia, autoimmune hemolytic anemia, and Evans syndrome) to improve the management, facilitate the differential diagnostic work-up, and document the clinical course under various treatments. Time points: at inclusion, after 6 months, after 12 months, then yearly …

autoimmune hemolytic anemia
thrombocytopenia
autoimmune thrombocytopenia
anemia
cytopenia
  • 5 views
  • 04 Mar, 2022
  • 1 location