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Found 56 clinical trials
Genotype and Phenotype Correlation in Hereditary Thrombotic Thrombocytopenic Purpura (Upshaw-Schulman Syndrome)

Hereditary thrombotic thrombocytopenic purpura (Upshaw-Schulman syndrome) is a rare disorder characterized by thrombocytopenia as a result of platelet consumption, microangiopathic hemolytic

  • 127 views
  • 27 Jan, 2021
  • 7 locations
.German TTP-Registry (Thrombotic Thrombocytopenic Purpura) (RGTTP)

Open, multi-center, observational, prospective cohort study, only disease-indicated treatment, in patients with clinically diagnosed acquired and congenital TTP regardless of gender, ethnicity, and comorbidities, over the age of 18 for 1.) prospective investigation of patients with TTP in an acute bout and during long-term follow and 2.) assessment of prevalence, …

  • 0 views
  • 05 Jun, 2022
The ConNeCT Study: Neurological Complications of TTP

Thrombotic thrombocytopenic purpura (TTP) is a rare condition, which has a very high risk of death if not recognised and given immediate treatment. TTP is caused by a very low level of an enzyme

  • 0 views
  • 17 Aug, 2021
  • 1 location
Plasma microRNA Levels and Some Cytokines Expression in Patients With ITP Primary Immune Thrombocytopenic Purpura (ITP) (microRNAITP)

Immune thrombocytopenia (ITP) is an autoimmune disease characterized by low platelet counts with or without mucocutaneous bleeding (McMillan, 2007). Like the majority of autoimmune diseases, ITP is an organ-specific disease, and abnormalities in the regulation of the immune system have been shown to play an important role in the initiation …

Accepts healthy volunteers
  • 0 views
  • 24 May, 2022
  • 1 location
ITP Registry and Accompanying Biospecimen Collection (ITP-Registry)

The objective of this ITP registry is to collect clinical information, including biosampling, from consenting patients with a variety of ITPs at different points in the course of their disease.

  • 0 views
  • 21 Apr, 2022
  • 1 location
French Registry of Adult Patients With Immune Thrombocytopenia and Autoimmune Hemolytic Anemia (CARMEN)

CARMEN is a national, real-world clinical registry of all adult patients with incident diagnosis of Immune thrombocytopenia (ITP) or Autoimmune Hemolytic anemia (AIHA) patients in France. It is aimed at describing ITP and AIHA clinical features, assessing the real-world risk-benefit ratio of treatments and adherence to guidelines for ITP and …

thrombocytopenia
anemia
cytopenia
autoimmune thrombocytopenia
  • 42 views
  • 22 Mar, 2022
  • 1 location
At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions

We are the missing link in clinical trials, connecting patients and researchers seamlessly and conveniently using a mobile health platform to advance medical research. We make it easy for patients to contribute to research for medical conditions that matter most to them, regardless of their location or ability to travel.

Accepts healthy volunteers
  • 261 views
  • 26 Jan, 2022
  • 1 location
Retrospective Analysis of the Efficiency of Caplacizumab in the Treatment of aTTP

The objective of this national, prospective, multi-centre observational study is to describe the prescription rational and practice in Germany, confirm the efficacy of caplacizumab in a real-world setting, and identify predicting factors in iTTP-patients with regard to persistent autoimmune activity, therapy guidance and risk of complications. The rational is to …

  • 0 views
  • 08 Jan, 2022
  • 1 location
Association of Platelet Parameters With Bleeding Severity in Children With ITP (ITP-APPS)

Patients with severe immune thrombocytopenia (ITP) present with similarly low platelet counts but varying bleeding symptoms, making it difficult to predict the disease course and to decide on an appropriate treatment plan. In a single-center study, platelet parameters including the immature platelet fraction, the absolute immature platelet count , and …

thrombocytopenia
autoimmune thrombocytopenia
platelet count
  • 12 views
  • 19 Jun, 2022
  • 3 locations
Gut Microbiota in ITP

Prospective, observational study to explore the significance of gut microbiome in the diagnosis of ITP, and to identify the predictive value of baseline gut microbiome for GC resistance/relapse.

blood tests
thrombocytopenia
platelet count
  • 0 views
  • 21 Mar, 2022
  • 1 location