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Found 56 clinical trials
Dietary Phytoestrogens as Risk Factors for Systemic Lupus Erythematosus (ISOLED)

The study aims at determining if dietary phytoestrogens can be risk factors for Systemic Lupus Erythematosus (SLE). Dietary enquiry and phytoestrogens measurements will be performed in blood and urine of patients with SLE in an active phase of the disease, in patient with other autoimmune diseases and in healthy volunteers. …

autoimmune disease
Accepts healthy volunteers
lupus
  • 53 views
  • 01 Feb, 2022
  • 1 location
A Prospective, One-arm and Open Clinical Study of Zanubrutinib in the Treatment of Immune Thrombocytopenia

To evaluate the safety and efficacy of zanubrutinib in the treatment of immune thrombocytopenia in 30 patients.

platelet count
rituximab
thrombocytopenia
steroid therapy
  • 0 views
  • 25 Mar, 2022
  • 1 location
Contribution of Anti-platelet Antibodies Identified With MAIPA Assay in the Demonstration of the Auto-immune Character of a Thrombocytopenia at Diagnosis

Immune thrombocytopenia (ITP) is an autoimmune disease but, paradoxically, and unlike other autoimmune diseases, antiplatelet antibodies are not used either for the diagnosis of the disease or for its prognosis. ITP is a diagnosis of exclusion retained after elimination of other pathologies leading to a thrombocytopenia. No major study has …

platelet count
acute leukemia
immune globulin
autoimmune disease
platelet aggregation
  • 0 views
  • 02 Jun, 2021
  • 1 location
Avatrombopag in the Treatment of Adult Immune Thrombocytopenia With Autoantibodies

This prospective, open-label, single-center, one-arm clinical trial aims at evaluating the efficacy and safety of avatrombopag in Chinese adult Immune Thrombocytopenia (ITP) patients with autoantibodies fail (due to intolerance or resistance) to eltrombopag or herombopag treatment.

platelet count
sjogren's syndrome
glucocorticoids
eltrombopag
avatrombopag
  • 0 views
  • 12 Aug, 2021
  • 1 location
Eltrombopag Combined With Low-dose Rituximab in the Treatment of Adult Immune Thrombocytopenia With Autoantibodies

This prospective, open-label, nonrandomized, multicenter clinical trial aims at comparing the efficacy and safety of combined use of eltrombopag with low-dose rituximab vs. the best available therapy(BAT)in adult immune thrombocytopenia with autoantibodies fail (due to intolerance or resistance) to first-line treatment.

platelet count
immunosuppressant
azathioprine
sjogren's syndrome
immune globulin
  • 0 views
  • 26 May, 2022
  • 1 location
The Combination of Sitagliptin and Danazol as the Treatment of Steroid-resistant/Relapse Immune Thrombocytopenia

Randomized, open-label, multicenter study to compare the efficacy and safety of combination of Sitagliptin and danazol versus danazol for the treatment of adults with steroid-resistant/relapse immune thrombocytopenia (ITP).

  • 0 views
  • 11 May, 2022
  • 1 location
Safety and Efficacy of Fecal Microbiota Transplantation

, dysbiotic bowel syndrome, MRSA enteritis, Pseudomembranous enteritis, idiopathic thrombocytopenic purpura (ITP), and atopy. Despite FMT appears to be relatively safe and efficacious in treating a

celiac disease
vancomycin
disease or disorder
obstruction
ulceration
  • 427 views
  • 23 Mar, 2022
  • 1 location
Eltrombopag With Standard Immunosuppression for Severe Aplastic Anemia

Background Severe aplastic anemia is a rare and serious blood disorder. It happens when the immune system starts to attack the bone marrow cells. This causes the bone marrow to stop making red blood cells, platelets, and white blood cells. Standard treatment for this disease is horse-ATG and cyclosporine, which …

white blood cells
platelet count
immunosuppressant
blood test
reticulocyte count
  • 114 views
  • 21 Apr, 2022
  • 1 location
Therapeutic Plasma Exchange in Adult Patients With Severe Sepsis

The incidence of sepsis (severe infection) has increased over the last four decades. Severe sepsis and septic shock are among the leading causes of death for patients admitted to critical care units with mortality ranging from 20-70% depending on totality of organ dysfunction. Outside of antibiotics and good bedside care, …

  • 0 views
  • 22 Mar, 2022
  • 2 locations
The United Kingdom Thrombotic Thrombocytopenic Purpura Registry (UK TTP Registry)

This is a UK (United Kingdom) based registry, involving all sites treating newly presenting Thrombotic Thrombocytopenic Purpura (TTP). From this registry, important epidemiological data will be

  • 0 views
  • 22 Jan, 2021
  • 1 location