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Found 181 clinical trials
Thrombosomes in Bleeding Thrombocytopenic Patients Study

This prospective, multicenter, randomized, open-label, Phase 2, parallel, dose ranging, multidose trial will enroll patients into 3 Thrombosomes dose groups and 1 control liquid stored platelets (LSP) group in order to evaluate, in a dose-escalation manner, the safety, and impact on bleeding, and the preliminary effect on coagulation measures of …

hematologic malignancy
myeloproliferative neoplasm
myeloproliferative disorder
platelet transfusion
stem cell transplantation
  • 0 views
  • 26 Nov, 2021
  • 6 locations
Aneurysmal Subarachnoid Hemorrhage Trial RandOmizing Heparin

A Blind-adjudication Multi-center Phase II Randomized Clinical Trial of Continuous Low-dose Intravenous Heparin Therapy in Coiled Low-grade Aneurysmal Subarachnoid Hemorrhage Patients with Significant Hemorrhage Burden.

aneurysm
subarachnoid hemorrhage
clot
heparin
paresis
  • 19 views
  • 26 Aug, 2021
  • 10 locations
Study of the Safety and Efficacy of Gemtuzumab Ozogamicin (GO) and Venetoclax in Patients With Relapsed or Refractory CD33+ Acute Myeloid Leukemia:Big Ten Cancer Research Consortium BTCRC-AML17-113

: treatment-related grade 3 or worse neutropenia and/or thrombocytopenia due to bone marrow hypocellularity present at the end of cycle one (day 28) with an additional 28 days allowed for count recovery (i.e

flow cytometry
tyrosine
refractory acute myeloid leukemia (aml)
gemtuzumab
venetoclax
  • 0 views
  • 21 Jan, 2022
  • 4 locations
Prospective Study on the Role of Intravenous Unfractionated Heparin Following Digital Replantation and Revascularization

bleeding, hematoma or heparin induced thrombocytopenia. The investigators would also assess the impact of categorical variables such as smoking status, mechanism of injury and comorbidities, on digital

  • 0 views
  • 07 Jun, 2021
  • 1 location
STUDY OF SURVIVAL AND FUNCTIONALITY IN CRYOPRESERVED PLATELETS

thrombocytopenia and non-immunological etiology, as well as in the management of traumatic or blood-related bleeding. surgical treatments. Given its wide margin of use and the constant demand for it for use within

  • 0 views
  • 13 Aug, 2021
  • 2 locations
Multidom Remote Monitoring of Patient With Advanced Pancreatic Cancer Treated With Florinox Using the PiCaDo Plateform

of severe toxicities including leukoneutropenia, thrombocytopenia, diarrhea, nausea-vomiting, anorexia, asthenia, weight loss and peripheral sensory neuropathy. Therefore, its indication is limited

pancreatic adenocarcinoma
adenocarcinoma
cancer chemotherapy
metastatic pancreatic cancer
  • 0 views
  • 08 Nov, 2021
  • 1 location
EUS Guided Portal-systemic Pressure Gradient Measurement

EUS approach was shown to correlate excellently with clinical parameters of portal hypertension including presence of varices, portal hypertensive gastropathy and thrombocytopenia. Furthermore, the

hepatocellular carcinoma
hypertension
spontaneous bacterial peritonitis
venous pressure
hepatitis
  • 0 views
  • 06 Dec, 2021
  • 1 location
Comparison of HYDROLINK™ and HeprAN™ mEmbranes in a Per Dialytic Heparin Weaning Strategy in Chronic Hemodialysis Patients

membrane would have an influence on platelet aggregation. It would also make it possible to avoid the risk of heparin-induced thrombocytopenia (HIT) by completely excluding heparin from the dialysis

chronic hemodialysis
anticoagulants
heparin
renal failure
dialysis
  • 0 views
  • 22 Dec, 2021
  • 1 location
Safety and Efficacy of Prolonged Use of Bivalirudin 4 Hours After ePCI (COBER Study)

activated coagulation time (ACT), ineffective thrombin binding to fibrin, non-specific protein binding and induced thrombocytopenia (HIT). Compared with UFH, LWMH has lower non-specific protein binding rate

bivalirudin
infarct
percutaneous coronary intervention
clot
myocardial infarction
  • 0 views
  • 12 Sep, 2021
  • 1 location
Conditioning Regimen for Allogeneic Hematopoietic Stem-Cell Transplantation

In this study, the investigators test 2 dose levels of thiotepa (5 mg/kg and 10 mg/kg) added to the backbone of targeted reduced dose IV busulfan, fludarabine and rabbit anti-thymocyte globulin (rATG) to determine the minimum effective dose required for reliable engraftment for subjects undergoing hematopoietic stem cell transplantation for …

lymphoproliferative disorder
x-linked lymphoproliferative disease
cytopenia
stem cell transplantation
hemoglobinopathy
  • 176 views
  • 26 Jan, 2022
  • 1 location