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Found 206 clinical trials
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Eltrombopag vs Standard Front Line Management for Newly Diagnosed Immune Thrombocytopenia (ITP) in Children

This is an investigator initiated, multicenter, open label, randomized phase 3 study for subjects with newly diagnosed ITP from ages 1 to less than 18 years old.

immunoglobulins
eltrombopag
platelet count
intravenous immunoglobulin
immune globulin
  • 10 views
  • 06 Oct, 2021
  • 11 locations
None
The Efficacy and Safety of Huaiqihuang Granule in Children With Chronic Primary Immune Thrombocytopenia

chronic primary immune thrombocytopenia (Qi Yin deficiency).

aptt
autoimmune thrombocytopenia
autoimmune disease
huaiqihuang
initial diagnosis
  • 0 views
  • 02 Aug, 2021
  • 14 locations
None
  • 0 views
  • 18 Feb, 2021
  • 1 location
None
The Safety Tolerability Pharmacokinetics and Preliminary Efficacy of HMPL-523 in Immune Thrombocytopenia Patients

This is a randomized, double blinded, placebo-controlled phase Ib clinical trial in adult patients with immune thrombocytopenia. Cross-over treatment will be allowed during the study.

treatment regimen
splenectomy
thrombocytopenia
anemia
  • 7 views
  • 26 Jan, 2021
  • 1 location
None
Eltrombopag Combined With Low-dose Rituximab in the Treatment of Adult Immune Thrombocytopenia With Autoantibodies

therapyBATin adult immune thrombocytopenia with autoantibodies fail (due to intolerance or resistance) to first-line treatment.

sjogren's syndrome
arthritis
mycophenolate
platelet count
recombinant human thrombopoietin
  • 0 views
  • 14 Jun, 2021
  • 1 location
None
Autoreactivity Threshold Analysis in Lupus and Immune Thrombocytopenia (Checkpoints ITP and SLE)

thrombocytopenia, and along the Believe study in SLE. This work would help to conclude whether or not the 'double hit' therapy may help to reset the immune system toward a more tolerogenic profile. The aim

immune tolerance
lupus
baff
thrombocytopenia
immune globulin
  • 0 views
  • 30 May, 2021
  • 2 locations
None
to Evaluate the Efficacy and Safety of Eltrombopag for Thrombocytopenia With Chronic HBV Infection

Primary Objective: To evaluate the efficacy of 6-week Eltrombopag to treat thrombocytopenia associated with chronic hepatitis B virus infection. Secondary Objective: To evaluate the efficacy and

  • 0 views
  • 10 Jul, 2021
  • 1 location
None
Avatrombopag for the Treatment of Thrombocytopenia After Donor Hematopoietic Stem Cell Transplant

This phase II trial studies the side effects and how well avatrombopag works for the treatment of thrombocytopenia after donor hematopoietic stem cell transplant. Thrombocytopenia is defined as

platelet count
thrombocytopenia
hematopoietic stem cell transplant
  • 0 views
  • 25 Jan, 2021
  • 1 location
None
The SOLID Platelet Study

Background Platelets are cell fragments in the blood that help it clot. Some people get very low platelet counts during a disease or treatment. Low platelet counts can cause severe bleeding. Some people are not helped by platelet transfusions at the standard transfusion rate. This is called platelet transfusion refractoriness …

pulmonary hemorrhage
platelet transfusion
hematologic malignancy
platelet count
clot
  • 0 views
  • 02 Jun, 2021
  • 1 location
None
Sirolimus Versus Sirolimus Plus Prednisolone for Kaposiform Hemangioendothelioma

Kaposiform hemangioendothelioma (KHE) is a rare vascular neoplasm that occurs predominantly in infancy or early childhood. KHE has a nearly equal sex ratio. The annual incidence of KHE has been estimated at 0.071 per 100,000 children. KHE presents with intermediate-malignant and locally aggressive characteristics but without distant metastases. This pilot …

propranolol
prednisolone
neutrophil count
hemangioendotheliomas
metastases
  • 50 views
  • 15 Mar, 2021
  • 1 location