Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 205 clinical trials
None
Dose Dense Rituximab for High Risk Newly Diagnosed Acute Immune Thrombocytopenic Purpura

The purpose of this study is to determine if a dose dense administration of Rituximab in newly diagnosed acute immune thrombocytopenic purpura (ITP) and determine relapse rate following this treatment. Correlative studies will be performed as outlined in the appendices. Quality of Life will be measured using the KIT as …

prednisone
rituximab
eltrombopag
kidney function tests
romiplostim
  • 0 views
  • 14 Aug, 2021
  • 1 location
None
COVID-19 : Study of INFLAmmasome and PLAtelets Functions

COVID-19 pandemic is a severe viral sepsis characterized by the occurrence of Acute respiratory distress syndrome (ARDS) whose pathophysiology is little described

respiratory distress
acute respiratory distress
covid-19
  • 0 views
  • 26 Jan, 2021
  • 1 location
None
Incidence of Snakebite Associated Thrombotic Microangiopathy & Role of Peripheral Blood Smear as a Predictor of Clinical Outcome

The aim of this study is to find the overall incidence of thrombotic microangiopathy in snakebite victims. As we know snakebite is a common in tropical regions. Many a times the early diagnosis of TMA is missed and precious time which could have helped in improving the patient prognosis is …

  • 0 views
  • 24 Jun, 2021
  • 1 location
None
A Natural History Study of Patients With GNE Myopathy and GNE-Related Diseases

Background GNE Myopathy is a disease that causes walking difficulties and increasing muscle weakness. It usually develops in young adults (between 20 and 30 years of age), and affects arm and leg muscles. HIBM is caused by mutations in a gene that may affect how the muscles function. Researchers want …

  • 0 views
  • 01 Dec, 2021
  • 1 location
None
Prospective Investigation of Antithrombin III Deficiency in Adult Patients With ECMO

There are publications showing a decrease in Antithrombin III levels of continuous flow and routine heparin therapy in adult patients undergoing Extracorporeal Membrane Oxygenation (ECMO) however, there is not enough data. One of the multifactorial causes affecting bleeding / thrombosis complications and ACT levels may be acquired Antithrombin III deficiency. …

  • 0 views
  • 30 Sep, 2021
  • 1 location
None
Biomarkers of Cytomegalovirus Fetal Infection and Disease

The purposes of this study are to determine 1) if the diagnosis of CMV fetal infection could be done directly in the maternal blood instead of requesting an amniocentesis and 2) if innovative technologies such as proteomic, transcriptomic, methylomic and lipidomic applied in fetal samples could allow the discovery of …

  • 5 views
  • 24 Jan, 2021
  • 2 locations
None
Hantavirus Registry Gathers Knowledge on Epidemiology Clinical Course Prognostic Factors and Molecular Characteristics for Hantavirus Infections and Their Complications (HantaReg)

Hantavirus disease are zoonotic infections and remain a clinical challenge with globally increasing incidence and multiple serious outbreak situations in Europe within the last years. Hantavirus disease encompasses two clinical syndromes, hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome (HCPS) caused by Old World and New World hantaviruses, …

  • 0 views
  • 11 May, 2021
  • 1 location
None
Oral Health Condition and Quality of Life in Children With Leukemia

Among the different types of cancer that most affect children, leukemia is the principal. One of the main treatments for leukemia is chemotherapy. Among the most common side effects of chemotherapy are nausea and/or vomiting, diarrhea, fatigue, alopecia, neuropathy, opportunistic infections, and oral mucositis. It is still necessary to establish …

cancer
lymphoid leukemia
  • 0 views
  • 26 Jul, 2021
  • 1 location
None
Safety and Efficacy of Fecal Microbiota Transplantation

The gut microbiota is critical to health and functions with a level of complexity comparable to that of an organ system. Dysbiosis, or alterations of this gut microbiota ecology, have been implicated in a number of disease states. Fecal microbiota transplantation (FMT), defined as infusion of feces from healthy donors …

ulcerative colitis
metabolic syndrome
purpura
celiac disease
colitis
  • 313 views
  • 24 Jan, 2021
  • 1 location
None
Predictors of Response to Neoadjuvant Docetaxel-Carboplatin Chemotherapy for Patients With Stage II and III Triple Negative Breast Cancer

Neoadjuvant (preoperative) chemotherapy is an interesting research tool which allows investigators to test new drugs and/or new schedules with a validated surrogate endpoint, pCR. It also represents an ideal model to evaluate the relationships between treatments and tumor biomarkers. Recent publications have shown that new molecular classifications of breast cancer …

carcinoma
anthracyclines
taxane
carboplatin
invasive breast cancer
  • 0 views
  • 04 Sep, 2021
  • 1 location