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Found 119 clinical trials
Featured trial
Tesla: Thrombectomy for Emergent Salvage of Large Anterior Circulation Ischemic Stroke

The primary objective of the trial is to establish the effectiveness of IAT (versus medical management) in patients with moderate-large infarcts (NCCT ASPECTS 2-5) at baseline, with adaptive enrichment to better define the upper limit of infarct volume for treatment eligibility. Furthermore, the investigators aim to determine whether certain subgroups …

  • 0 views
  • 08 Jan, 2022
  • 1 location
Outcome in Patients Treated With Intraarterial Thrombectomy - optiMAL Blood Pressure Control (OPTIMAL-BP)

Recent endovascular thrombectomy (EVT) trial have proven the effectiveness of intraarterial revascularization in patients with larger cerebral artery occlusion. The success rate of EVT is close

ischemia
cerebral infarction
stroke
arterial occlusion
hypertension
  • 0 views
  • 22 Aug, 2021
  • 1 location
SELECT2: A Randomized Controlled Trial to Optimize Patient's Selection for Endovascular Treatment in Acute Ischemic Stroke (SELECT2)

SELECT 2 evaluates the efficacy and safety of endovascular thrombectomy compared to medical management alone in acute ischemic stroke patients due to a large vessel occlusion in the distal ICA

  • 36 views
  • 14 May, 2022
  • 28 locations
Hemodynamic Optimization of Cerebral Perfusion After Endovascular Therapy in Patients With Acute Ischemic Stroke

Mechanical thrombectomy is a very effective treatment in patients who have suffered an acute ischemic stroke associated with intracranial large vessel occlusion. However, less than half of the

  • 0 views
  • 01 Oct, 2021
  • 1 location
Efficacy and Safety of Butylphthalide for Acute Ischemic Stroke Patients Receiving Intravenous Thrombolysis or Endovascular Treatment (BAST)

with the evolution of using iv. recombinant tissue plasminogen activatorrtPA and mechanical thrombectomy in acute ischemic strokeAISpatients, it is still undefined whether combination therapy with dl

  • 4 views
  • 05 Mar, 2022
  • 1 location
Multi-arm Optimization of Stroke Thrombolysis (MOST)

-PA or 0.25mg/kg IV tenecteplase or TNK) within three hours of symptom onset. Patients may also receive endovascular thrombectomy (ET) per usual care. Time of onset is defined as the last time the

  • 173 views
  • 20 Feb, 2022
  • 66 locations
Extending the Time Window for Tenecteplase by Effective Reperfusion in Patients With Large Vessel Occlusion

Patients presenting to the emergency department with an acute ischemic stroke due to a large vessel occlusion eligible for thrombectomy and target mismatch on computed tomography perfusion

stenosis
stroke
thrombolytic agent
probe
plasminogen
  • 0 views
  • 01 Jul, 2021
  • 7 locations
China Antihypertensive Trial in Acute Ischemic Stroke II (CATIS-2)

score of ≥21, Glasgow Coma Scale score <8, preceding moderate or severe dependency (modified Rankin scale score 3-5), revascularization, intravenous thrombolytic therapy or mechanical thrombectomy

  • 0 views
  • 12 May, 2022
  • 1 location
Ischemic Post-conditioning in Acute Ischemic Stroke Thrombectomy (PROTECT)

determine the safety and tolerability of ischemic post-conditioning in patients with acute ischemic stroke who are treated with mechanical thrombectomy.

  • 0 views
  • 23 Mar, 2022
  • 1 location
Randomized Study of Bailout Intracranial Angioplasty for Unsuccessful Thrombectomy

Unfavorable outcomes were associated with failed recanalization of acute large vessel occlusions (LVO). The failed recanalization rate of mechanical thrombectomy (MT) was 12-41% reported in

  • 0 views
  • 16 Dec, 2021
  • 1 location