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Found 39 clinical trials
A Cardiac Disease Quality of Life Study (UPLIFT)

A prospective, longitudinal, non-comparator, non-randomized observational cohort study to assess the quality of life in adult patients affected by hypertrophic cardiomyopathy and thoracic aortic dilatations who are not amenable to surgery, as well as those affected radiation-induced cardiac disease caused by radiation therapy.

heart disease
hypertrophic cardiomyopathy
  • 14 Jul, 2022
  • 1 location
Pathogenetic Basis of Aortopathy and Aortic Valve Disease (TAA)

The main purpose of this study is to define the complex genetic and pathogenic basis of thoracic aortic aneurysm (TAA) and other forms of aortopathy and/or aortic valve disease by identifying

thoracic aortic aneurysm
aortic disease
marfan syndrome
tricuspid disease
  • 24 Mar, 2022
  • 1 location
TOtal tRansfemoral branCHed endovasCular tHoracoabdominal Aortic Repair Registry

The purpose of the registry is to evaluate the peri-operative, short-, and mid- outcomes of endovascular treatment of thoracoabdominal aneurysms with multibranched endografts via total transfemoral approach for visceral vessels cannulation using steerable sheaths

  • 20 Jul, 2022
  • 7 locations
Safety Efficacy and Cost Analysis of the Conformable Thoracic Stent Graft With ACTIVE CONTROL

Study Design This is a prospective, multicenter, non-randomized clinical study in patients presenting thoracic aortic pathologies. Following a baseline assessment, the implantation procedure will be performed according to the Instructions for Use and local routine practice. A follow-up visit will be performed 30 days, 6, 12,24 and 36 months after …

  • 29 Sep, 2021
  • 3 locations
Real-World Data Collection of the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis When Used as a Bridging Stent With Branched and Fenestrated Endografts in the Treatment of Aortic Aneurysms Involving the Renal-Mesenteric Arteries (EMBRACE)

Multicenter, single-arm retrospective and prospective registry is being conducted to confirm the clinical performance and safety of GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis when used as a Bridging Stent with Branched and Fenestrated Endografts in the Treatment of Aortic Aneurysms Involving the Renal-Mesenteric Arteries.

  • 26 Apr, 2022
  • 1 location
Modified Preloaded System for Renal Arteries in Fenestrated Endografting (MPSRA) (MPSRA)

Advanced Endovascular repair of aneurysms and dissections involving thoraco-abdominal (type I-IV) and complex abdominal (juxta and para-renal) aorta is a ground-gaining procedure allowing favorable results in high surgical risk patients. The availability of iliac vessels navigation and the major role of lower leg perfusion in order to decrease the risk …

aortic aneurysm
  • 15 Mar, 2022
  • 1 location
Study of Treatment of Thoracic Aortic Aneurysms and Dilatation in Combination With Tricuspid and Bicuspid Aortic Valves.

Clarification of indications for surgical correction in patients with borderline expansion of the ascending aorta

Accepts healthy volunteers
  • 15 May, 2022
  • 1 location
Antibiotic Prophylaxis for TEVAR

The infection rate of thoracic endovascular aortic repair (TEVAR) is unknown due to a lack of epidemiological data. The rate currently available comes from researches conducted decades ago, when open surgery was the standard of care. Because of the potentially fatal consequences of a stent graft infection in the thoracic …

  • 19 Jun, 2022
  • 1 location
ENDOBARC-S Study: "Endovascular Branched Stent-grafts for Aortic ARCh Pathologies in Spain"

The ENDOBARC-S post-market clinical follow-up study is undertaken to evaluate the prevention of death related to aortic arch pathologies when treated by branch stent graft systems (Nexus stent-graft system®, Relay Branch® or Zenith arch branch graft®), with proximal landing at zone 0. The secondary objective is to evaluate the safety …

  • 23 Apr, 2022