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Found 42 clinical trials
Detection of Hypoxia in Human Thoracic Aorta Using Pimonidazole Hydrochloride

This is a prospective study designed to determine the safety and value of Hypoxyprobe-1 (pimonidazole hydrochloride (-HCl)) to detect levels of tissue hypoxia in patients presenting with ascending aortic aneurysm.

open surgery
aortic valve insufficiency
human chorionic gonadotropin
pimonidazole hydrochloride
  • 13 views
  • 14 Feb, 2022
  • 1 location
A Clinical Study of the Safety and Efficacy of the Relay Thoracic Stent-Graft in Patients With Thoracic Aortic Pathologies

A Phase II study to evaluate the safety and efficacy of the Relay Stent Graft in patients with descending thoracic aneurysms.

  • 30 views
  • 08 Nov, 2020
  • 1 location
Physician-Modified Fenestrated and Branched Aortic Endografting for TAAA

The primary clinical objective of this study is to evaluate the safety and effectiveness of a physician-modified, fenestrated and branched aortic endoprosthesis for the treatment of thoracoabdominal aortic aneurysms (TAAAs). The goal of the primary analysis is to demonstrate both the safety and effectiveness of using a physician-modified fenestrated Cook …

  • 0 views
  • 26 Apr, 2022
  • 1 location
Evaluation of Aortic Stiffness as a Prognostic Indicator of Aortic Dilatation in Patients With Bicuspid Aortic Valve by Multimodal Imaging (IRM-BAO)

The objective is the development and validation of morphological markers informative of aortic dilatation in order to improve the precision of the risk of aneurysm of the thoracic aorta and of acute aortic syndrome for patients with bicuspid aortic valve (BAV). The primary objective of this study is to demonstrate …

  • 0 views
  • 07 Apr, 2022
  • 1 location
Treatment in Thoracic Aortic Aneurysm: Surgery vs Surveillance (TITAN:SvS)

The ascending aorta conducts blood from the heart to the rest of the body. The ascending aorta can become enlarged, and the risk of tearing and rupturing becomes higher with larger aorta. When the ascending aorta tears or ruptures, the risk dying is high even if surgery is done as …

  • 124 views
  • 13 May, 2022
  • 18 locations
RelayPro Thoracic Stent-Graft in Subjects With Thoracic Aortic Aneurysms and Penetrating Atherosclerotic Ulcers (RelayPro-A)

Investigate the safety and effectiveness of the RelayPro Thoracic Stent-Grafts in subjects with thoracic aortic aneurysms (TAA) and penetrating atherosclerotic ulcers (PAU) of the descending

  • 58 views
  • 27 Feb, 2022
  • 15 locations
Evaluation of the GORE® TAG® Thoracic Branch Endoprosthesis (TBE Device) in the Treatment of Lesions of the Aortic Arch and Descending Thoracic Aorta (Zone 0/1) (SSB 11-02)

The objective of this study is to determine whether the GORE TAG Thoracic Branch Endoprosthesis is safe and effective in treating lesions of the aortic arch and descending thoracic aorta.

  • 2 views
  • 26 Jan, 2022
  • 39 locations
Evaluation of the GORE® TAG® Thoracic Branch Endoprosthesis (TBE Device) in the Treatment of Lesions of the Aortic Arch and Descending Thoracic Aorta (Zone 2) (SSB 11-02)

The objective of this study is to determine whether the GORE® TAG® Thoracic Branch Endoprosthesis is safe and effective in treating lesions of the aortic arch and descending thoracic aorta.

  • 0 views
  • 24 Mar, 2022
  • 34 locations
Evaluation of the GORE® EXCLUDER® Thoracoabdominal Branch Endoprosthesis in the Treatment of Thoracoabdominal and Pararenal Aortic Aneurysms (TAMBE)

Prospective, non-randomized, , multicenter study with two independent arms: Primary Study Arm - TAAA and Pararenal aneurysms requiring only TAMBE System. Hypothesis-driven analysis. Up to 40 additional subjects may be implanted in Continued Access Phase under t the Primary Study Arm only Secondary Study Arm - TAAA requiring TAMBE System …

  • 4 views
  • 25 Mar, 2022
  • 44 locations
Evaluation of Branch Endografts in the Treatment of Aortic Aneurysms

The purpose of this study is to collect information on the Cook Zenith t-Branch endovascular stent-graft system for the treatment of aortic aneurysms.

  • 38 views
  • 30 Jan, 2022
  • 1 location