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Found 37 clinical trials
Freiburg ZNS-NHL Study

The purpose of this study is to determine whether combined chemotherapy [rituximab plus high dosage methotrexate (max. 2 cycles) followed by arabinoside/thiotepa (max. 2 cycles) followed

  • 2 views
  • 07 Nov, 2020
  • 1 location
Auto Transplant for High Risk or Relapsed Solid or CNS Tumors

This is a standard of care treatment guideline for high risk or relapsed solid tumors or CNS tumors consisting of a busulfan, melphalan, thiotepa conditioning (for solid tumors) or carboplatin

cns neoplasm
mg++
cns lymphoma
cancer
desmoplastic
  • 77 views
  • 02 Jun, 2021
  • 1 location
Conditioning Regimen for Allogeneic Hematopoietic Stem-Cell Transplantation

In this study, the investigators test 2 dose levels of thiotepa (5 mg/kg and 10 mg/kg) added to the backbone of targeted reduced dose IV busulfan, fludarabine and rabbit anti-thymocyte globulin

follicle-stimulating hormone
malnutrition
hysterectomy
antithymocyte globulin
familial hemophagocytic lymphohistiocytosis
  • 176 views
  • 19 Jul, 2021
  • 1 location
Transplantation Using Reduced Intensity Approach for Patients With Sickle Cell Disease From Mismatched Family Donors of Bone Marrow

-matched related donors. Preparation before transplant includes the chemotherapy drugs hydroxyurea, fludarabine, thiotepa, anti-thymocyte globulin, and cyclophosphamide. It also includes radiation.

hydroxyurea
preparative regimen
hemoglobin s
sickle cell trait
anti-thymocyte globulin
  • 33 views
  • 13 Feb, 2021
  • 1 location
Autologous Stem Cell Transplantation for Progressive Systemic Sclerosis

toxicity we reduce the dose of Cyclophosphamide (CYC) for mobilisation to 2x1g. Especially in patients with cardiac manifestations we also modify the conditioning regimen by adding thiotepa and

MRSS
chest ct
pulmonary function test
diffuse cutaneous systemic sclerosis
alveolitis
  • 50 views
  • 26 Jan, 2021
  • 1 location
Donor Stem Cell Transplant After Chemotherapy for the Treatment of Recurrent or Refractory High-Risk Solid Tumors in Pediatric and Adolescent-Young Adults

has come back (recurrent) or does not respond to treatment (refractory). Chemotherapy drugs, such as fludarabine, thiotepa, etoposide, melphalan, and rabbit anti-thymocyte globulin work in different

stem cell transplant
melphalan
malignant peripheral nerve sheath tumor
desmoplastic
glomerular filtration rate
  • 0 views
  • 03 Mar, 2021
IS-free Treg HaploHCT

>Radiation-Total Myeloid and Lymphoid Irradiation (TMLI Chemotherapy (Fludarabine, Thiotepa, Cyclophosphamide plus Mesna) Infusion of haplo Treg-enriched donor cells (experimental therapy

gilbert's syndrome
myelodysplastic syndromes
ejection fraction
fludarabine
cell transplantation
  • 0 views
  • 16 Jul, 2021
  • 1 location
Chemotherapy and Donor Stem Transplant for the Treatment of Patients With High Grade Brain Cancer

. Chemotherapy drugs, such as fludarabine, thiotepa, etoposide, melphalan, and rabbit anti-thymocyte globulin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping

  • 0 views
  • 02 Mar, 2021
  • 1 location
Cord Blood Transplant With OTS for the Treatment of HIV Positive Hematologic Cancers

cells that help to produce mature blood cells, including immune cells. Drugs used in chemotherapy, such as fludarabine, cyclophosphamide, and thiotepa, work in different ways to stop the growth of tumor

myeloid leukemia
blast crisis
flow cytometry
bone marrow failure
cancer
  • 0 views
  • 03 Sep, 2021
  • 5 locations
A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT

, etoposide, ifosfamide, and thiotepa, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Radiation

mg++
neutrophil count
cancer
stem cell transplantation
brain tumor
  • 0 views
  • 01 Sep, 2021
  • 4 locations