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Found 12 clinical trials
Treatment for Calcium Phosphate Kidney Stone Disease

The investigators will examine in two studies whether citric acid or potassium citrate can reduce calcium phosphate saturation in urine of Calcium Phosphate stone formers.

  • 212 views
  • 22 Mar, 2022
  • 1 location
Occurrence of Dyskalemia With Treatment for Hypertension (OK)

Hypertension is a major public health issue associated with significant morbidities and mortality. Fixed-dose combination (FDC) pills, combining 2 or more classes of antihypertensive medications have considerable appeal because these drugs may reduce blood pressure more effectively and efficiently compared to monotherapy. However, because FDC medication causes 'dyskalemia', the occurrence …

systolic blood pressure
telmisartan
amlodipine 5 mg
Accepts healthy volunteers
hypertension
  • 0 views
  • 24 Mar, 2022
  • 1 location
Preventing Metabolic Side Effects of Thiazide Diuretics With KMgCitrate

Chlorthalidone (CTD) may produce various metabolic disturbances, including hypokalemia, activation of Renin-Angiotensin- Aldosterone (RAA) system, oxidative stress, dyslipidemia, Fibroblast growth factor 23 (FGF23) synthesis, and magnesium depletion. These factors may interact with each other to contribute to the development of insulin resistances and metabolic syndrome. Smaller studies have suggested that …

chlorthalidone
metabolic syndrome
diuretics
insulin
angiotensin
  • 24 views
  • 21 Mar, 2022
  • 3 locations
Ertugliflozin in Chronic Heart Failure

studies that form the basis of current practice with loop diuretics as well as all studies looking at add-on thiazide therapy (current guideline-recommended adjuvant). The second is to generate a

diuretics
edema
chronic heart failure
furosemide
heart failure
  • 0 views
  • 24 May, 2022
  • 1 location
Mechanism of Hypertension Treatments in Liver Transplant Recipients (BLOCK LTR-HTN)

recommendation. There is some new evidence suggesting that another class of medications, called thiazide-like diuretics, might be beneficial to lower blood pressure in liver transplant recipients. The current

systolic blood pressure
chlorthalidone
ambulatory blood pressure monitoring
diuretics
immunosuppression
  • 0 views
  • 04 Oct, 2022
  • 1 location
Spironolactone in CKD Enabled by Chlorthalidone: PILOT (SPICE PILOT)

potassium (K). This side effect occurs frequently in those who suffer from CKD. Alternatively, chlorthalidone (CTD) is a thiazide-like diuretic used for treating hypertension and decreases serum K. In this

antihypertensive drugs
ace inhibitor
hypertension
  • 0 views
  • 23 Mar, 2022
  • 1 location
Efficacy and Safety of a Single-pill Fixed Combination of Sufficient Losartan/Hydrochlorothiazide in Chinese Hypertensive Patients

angiotensin receptor blocker (ARB) combined with thiazide diuretic (DIU), which is the preferred combination for most hypertension guidelines. However, the efficacy and safety of losartan 100 mg

systolic blood pressure
angiotensin converting enzyme
ambulatory blood pressure monitoring
diuretics
angiotensin
  • 0 views
  • 06 Feb, 2022
  • 1 location
ACES - ACE Inhibitors Combined With Exercise for Seniors With Hypertension (ACES)

The purpose of this project is to conduct a randomized, controlled trial (RCT) to determine if choice of antihypertensive medication influences changes in functional status and other cardiovascular risk factors among older persons with hypertension when combined with physical exercise.

systolic blood pressure
aerobic exercise
perindopril
hypertension
antihypertensive drugs
  • 175 views
  • 24 May, 2022
  • 3 locations
Parathyroid Allotransplantation in Medically Refractory Hypoparathyroidism (PATH)

Options for treatment of severe, refractory hypocalcemia are limited for the thousands of patients in the United States who suffer from hypoparathyroidism. Parathyroid allotransplantation is an emerging treatment that provides hope for these individuals. Currently, this therapy has only been successfully provided by a few centers in the world. In …

hypocalcemia
calcium
  • 0 views
  • 10 Apr, 2022
  • 1 location
Treatment of Resistant Hypertension: Cohort Study

patients with treatment resistant hypertension: an aldosterone receptor blocker (e.g. spironolactone), a loop diuretic, a thiazide in large daily dose, an alpha 1 selective blocker or a beta 1 selective

  • 0 views
  • 06 Nov, 2021
  • 13 locations