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Found 10 clinical trials
Study of Safety of CSJ117 in Participants With Moderate to Severe Uncontrolled Asthma

participants treated with medium or high dose ICS plus LABA alone or with additional asthma controllers (additional controllers allowed: LTRA, LAMA, Theophylline and its derivatives), who have completed the

  • 15 May, 2022
  • 49 locations
Theophylline Treatment for Pseudohypoparathyroidism

will test the efficacy of theophylline, a phosphodiesterase inhibitor, in pseudohypoparathyroidism. The investigators hypothesize that theophylline will cause weight loss, improve glucose tolerance and

  • 04 Mar, 2022
  • 1 location
Theophylline Treatment for Pseudohypoparathyroidism - Children 2-12 Years Old

trial and open-label extension study will test the efficacy of theophylline, a phosphodiesterase inhibitor, in pseudohypoparathyroidism. We hypothesize that theophylline will cause weight loss, slow the

  • 07 Oct, 2021
  • 1 location
Effectiveness of Low-Dose Theophylline for the Management of Biomass-Associated COPD

test the effectiveness of low dose theophylline compared to standard therapy among adults with biomass-related COPD in Uganda with the aim to assess whether low-dose theophylline improves respiratory

  • 09 May, 2022
  • 1 location
Helping Olfaction and Nutrition On Renal Replacement

This clinical trial examines whether nasal theophylline administration can improve olfaction and nutrition in hemodialysis patients.

kidney replacement
  • 26 Jan, 2021
  • 1 location
Preventing Acute Kidney Injury (AKI) in Pediatric Patients (AKI)

The purpose of this study is to compare the effects of peri-operative administration of Aminophylline versus Saline placebo in the preservation of renal function and the attenuation of renal injury in pediatric patients undergoing open heart surgery.

  • 02 May, 2022
  • 1 location
Mesenchymal Stem Cells for The Treatment of Chronic Obstructive Pulmonary Disease

The clinical study with UMC119-06 is designed to investigate the safety in patients with Chronic Obstructive Pulmonary Disease. This will be a dose escalation, open label, single-center study in adult with chronic obstructive pulmonary disease. UMC119-06 is ex vivo cultured human umbilical cord tissue-derived mesenchymal stem cells product which is …

  • 01 May, 2021
  • 1 location
Phase II Trial of Disulfiram With Copper in Metastatic Breast Cancer

The aim of the study is to establish clinical evidence for introducing disulfiram and cooper as an active therapy for metastatic breast cancer upon failure of conventional systemic and/or locoregional therapies. Analyses of the following objectives will be performed in the population of patients with metastatic breast cancer: Primary efficacy …

biomarker analysis
breast cancer
dna damage
major surgery
  • 19 May, 2021
  • 1 location
The Effect of Platelet Rich Pasma on Strenal Healing Post Median Strenotomy in Patients Undergoing Open Heart Surgery

Platelet-rich plasma (PRP) is an autologous concentration of human platelets in a small volume of plasma. Because it is an autogenous preparation, PRP is inherently safe and therefore free from concerns over transmissible diseases such as HIV and hepatitis. Its power of regeneration already proved by orthopedics and dentists in …

open heart surgery
Accepts healthy volunteers
  • 21 Mar, 2022
  • 1 location
Functional Lung MRI for Early Treatment Response Assessment for Patients With Eosinophilic Asthma

Patients with severe eosinophilic asthma will be placed on biologics if they continue to be uncontrolled despite maximized inhalation therapy or if they are only controlled under oral corticosteroids. Among biologics, 80% of patients respond to treatment and improve clinically, but approximately 20% are non-responders and up to date no …

  • 04 Sep, 2021
  • 1 location