Found 70 clinical trials
A Study of IMR-687 in Subjects With Beta Thalassemia
A Study to Evaluate the Safety and Tolerability of IMR-687 in Subjects with Beta Thalassemia
- 10 views
- 10 Jun, 2021
- 39 locations
Study to Evaluate the Efficacy Safety Tolerability Pharmacokinetics and Pharmacodynamics of IONIS TMPRSS6-LRx
dependent -Thalassemia Intermedia.
- 0 views
- 28 Jan, 2021
- 25 locations
Allograft for Sickle Cell Disease and Thalassemia
anemias. The patient cohort to be studied: Those patients with severe sickle cell disease and thalassemia who have risk factors for high mortality and morbidity related to their disease
- 28 views
- 18 Feb, 2021
- 1 location
L-arginine Versus Sildenafil in Children With Beta Thalassemia Associated With Pulmonary Hypertension
This study compares L-arginine Versus Sildenafil as treatment for pulmonary hypertension in Children with Beta Thalassemia
- 6 views
- 22 Jan, 2021
- 1 location
Iron Balance Study of Deferasirox Deferoxamine and the Combination of Both
Subjects with thalassemia major require regular transfusion therapy to sustain life. The iron present in the transfused blood remains in the body where it can cause a variety of organ
- 28 views
- 07 Nov, 2020
- 1 location
Interferon and Ribavirin Treatment in Patients With Hemoglobinopathies
Worldwide, several studies report that 4.4% to 85.4% of thalassemia patients were positive for anti hepatitis C antibodies. Recently, three different studies reported the efficacy and the
- 0 views
- 07 Nov, 2020
- 1 location
Hematopoietic Stem Cell Transplantation for Patients With Thalassemia Major: A Multicenter Prospective Clinical Study
The only curative therapy for thalassemia major remains the replacement of the defective erythropoiesis by allogeneic hematopoietic stem cell transplantation(allo-HSCT). We conduct a prospective
- 1 views
- 23 Jan, 2021
- 1 location
Study of Safety & PK of Luspatercept (ACE-536) in Pediatric Participants Who Require Regular RBC Transfusions Due to Beta ( )-Thalassemia.
This is a Phase 2a study to evaluate the safety and pharmacokinetics (PK) of luspatercept in pediatric participants who require regular red blood cell transfusions due to -thalassemia.
- 4 views
- 18 Jun, 2021
- 8 locations
Safety Tolerability Pharmacokinetics (PK) Pharmacodynamics (PD) and Preliminary Efficacy of VIT-2763 in -thalassaemia
non-transfusion-dependent Beta-thalassemia (NTDT).
- 17 views
- 14 Jun, 2021
- 16 locations
A Safety and Efficacy Study Evaluating CTX001 in Subjects With Transfusion-Dependent -Thalassemia
This is a single-arm, open-label, multi-site, single-dose Phase 1/2 study in subjects with transfusion-dependent -thalassemia (TDT). The study will evaluate the safety and efficacy of autologous
- 74 views
- 22 Feb, 2021
- 12 locations