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Found 67 clinical trials
A Study of IMR-687 in Subjects With Beta Thalassemia

A Study to Evaluate the Safety and Tolerability of IMR-687 in Subjects with Beta Thalassemia

beta thalassemia
  • 10 views
  • 25 Jan, 2021
  • 8 locations
  • 0 views
  • 28 Jan, 2021
  • 25 locations
Allograft for Sickle Cell Disease and Thalassemia

anemias. The patient cohort to be studied: Those patients with severe sickle cell disease and thalassemia who have risk factors for high mortality and morbidity related to their disease

  • 28 views
  • 18 Feb, 2021
  • 1 location
Iron Balance Study of Deferasirox Deferoxamine and the Combination of Both

Subjects with thalassemia major require regular transfusion therapy to sustain life. The iron present in the transfused blood remains in the body where it can cause a variety of organ

serum ferritin level
diabetes
chelation therapy
deferasirox
blood transfusion
  • 28 views
  • 07 Nov, 2020
  • 1 location
L-arginine Versus Sildenafil in Children With Beta Thalassemia Associated With Pulmonary Hypertension

This study compares L-arginine Versus Sildenafil as treatment for pulmonary hypertension in Children with Beta Thalassemia

hypertension
arginine
sildenafil
beta thalassemia
  • 6 views
  • 22 Jan, 2021
  • 1 location
Interferon and Ribavirin Treatment in Patients With Hemoglobinopathies

Worldwide, several studies report that 4.4% to 85.4% of thalassemia patients were positive for anti hepatitis C antibodies. Recently, three different studies reported the efficacy and the

ribavirin
thalassemia
hepatitis b
  • 0 views
  • 07 Nov, 2020
  • 1 location
Hematopoietic Stem Cell Transplantation for Patients With Thalassemia Major: A Multicenter Prospective Clinical Study

The only curative therapy for thalassemia major remains the replacement of the defective erythropoiesis by allogeneic hematopoietic stem cell transplantation(allo-HSCT). We conduct a prospective

thymoglobulin
ineffective erythropoiesis
stem cell transplantation
cyclosporine
busulfan
  • 1 views
  • 23 Jan, 2021
  • 1 location
Safety Tolerability Pharmacokinetics (PK) Pharmacodynamics (PD) and Preliminary Efficacy of VIT-2763 in -thalassaemia

non-transfusion-dependent Beta-thalassemia (NTDT).

thalassemia intermedia
blood transfusion
  • 17 views
  • 15 Feb, 2021
  • 16 locations
A Safety and Efficacy Study Evaluating CTX001 in Subjects With Transfusion-Dependent -Thalassemia

This is a single-arm, open-label, multi-site, single-dose Phase 1/2 study in subjects with transfusion-dependent -thalassemia (TDT). The study will evaluate the safety and efficacy of autologous

stem cell transplantation
busulfan
beta thalassemia
hemoglobin e
thalassemia
  • 74 views
  • 22 Feb, 2021
  • 12 locations
A Study to Evaluate Long-term Safety in Subjects Who Have Participated in Other Luspatercept (ACE-536) Clinical Trials

A Phase 3b, open-label, single-arm, rollover study to evaluate the long-term safety of luspatercept, to the following subjects: Subjects receiving luspatercept on a parent protocol at the time of their transition to the rollover study, who tolerate the protocol-prescribed regimen in the parent trial and, in the opinion of the …

ace-536
hysterectomy
cancer
luspatercept
growth factor
  • 82 views
  • 27 Jan, 2021
  • 125 locations