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Found 3 clinical trials
Thal-Fabs: Reduced Toxicity Conditioning for High Risk Thalassemia

The purpose of this study is to evaluate a novel transplant strategy for the long-term benefit of patients with transfusion dependent high-risk thalassemia.

  • 0 views
  • 05 Jul, 2022
  • 1 location
Low Dose Iron Chelation as TReatment of Oxidative Damage in Sickle Cell Disease (TROS)

> Adult patients with sickle cell anemia (HbSS) or HbS-β0-thalassemia (HbSβ0-thal) visiting the outpatient-clinic of the Academic Medical Center, Amsterdam will be asked for inclusion in the study.

iron
thalassemia
thal
  • 0 views
  • 05 Jun, 2022
Study of Safety & PK of Luspatercept (ACE-536) in Pediatric Participants Who Require Regular RBC Transfusions Due to Beta (β)-Thalassemia.

This is a Phase 2a study to evaluate the safety and pharmacokinetics (PK) of luspatercept in pediatric participants who require regular red blood cell transfusions due to β-thalassemia. The study will be conducted in 2 parts: Part A will be in adolescent participants aged 12 to <18 years with two …

blood transfusion
progesterone
hysterectomy
ace-536
hemoglobin e
  • 6 views
  • 04 Jun, 2022
  • 1 location