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Found 263 clinical trials
Aromatase Inhibitors and Weight Loss in Severely Obese Men With Hypogonadism

The investigators have preliminary data suggesting that obese patients with hypogonadotropic hypogonadism (HHG) have minimal benefit from testosterone therapy likely because of its conversion to

behavior modification
testosterone level
gonadotropin
fasting
androgen deficiency
  • 1121 views
  • 24 Mar, 2022
  • 1 location
Enzalutamide With and Without Ribociclib for Metastatic, Castrate-Resistant, Chemotherapy-Naive Prostate Cancer That Retains RB Expression

(metastatic), is chemotherapy naïve, and retains retinoblastoma expression. Testosterone can cause the growth of prostate cancer cells. Hormone therapy using enzalutamide may fight prostate cancer by blocking

liver metastasis
tumor cells
bone lesion
absolute neutrophil count
gilbert's syndrome
  • 112 views
  • 23 Apr, 2022
  • 4 locations
Oxandrolone Rotator Cuff Trial (ORCT)

This study is about healing after a rotator cuff tear repair procedure. We hope to learn if a biologic medication: Oxandrolone, a synthetic derivative of the human hormone Testosterone (the

oxandrolone pill
rotator cuff repair
full thickness rotator cuff tear
  • 174 views
  • 10 Feb, 2022
  • 1 location
Testing the Effects of Oxybutynin for the Treatment of Hot Flashes in Men Receiving Hormone Therapy for Prostate Cancer

. Androgen deprivation therapy decreases testosterone and other androgens through medications or surgical removal of the testicles. Relative to placebo, low- or high-dose oxybutynin may reduce hot flashes in

  • 5 views
  • 26 Jul, 2022
  • 88 locations
Improving Quality of Life of Prostate Cancer Survivors With Androgen Deficiency

The purpose of this phase II trial is to determine the efficacy and safety of testosterone replacement therapy (TRT) in improving the symptoms of androgen deficiency and health-related quality

prostate specific antigen
prostatectomy
testosterone
serum testosterone
androgens
  • 0 views
  • 09 Feb, 2022
  • 2 locations
Relative Contributions of Predictors of Hyperandrogenism in Older vs. Young Women With PCOS (SHK001)

(PCOS) in a cross-sectional, physiological study. The investigators hypothesize that hyperinsulinemia is a stronger independent predictor of free testosterone (T) in older reproductive aged (vs. young

hyperandrogenism
hyperinsulinemia
testosterone level
gonadotropin
oligomenorrhea
  • 335 views
  • 09 Jul, 2022
  • 1 location
Androgen Blockade and Progesterone Augmentation of Gonadotropin Secretion (CRM010)

This study is trying to find out if flutamide (a medication that blocks the effects of testosterone) may help normalize an aspect of pituitary function (specifically, gonadotropin surge

Accepts healthy volunteers
  • 0 views
  • 26 May, 2022
  • 1 location
Non-fucosylated Anti-CTLA-4 (BMS-986218) + Degarelix Acetate vs. Degarelix Acetate Alone in Men With High-risk Localized Prostate Cancer

The purpose of this study is to see whether immunotherapy with BMS-986218 added to degarelix (which suppresses testosterone) given prior to surgery can decrease the chance that cancer will come

  • 0 views
  • 04 Nov, 2021
  • 1 location
Effects of Inositol Alone or Associated With Alpha-lipoic Acid in Polycystic Ovary Syndrome Treatment

> clinical data: height, weight, BMI, waist and hip circumference, blood pressure, Ferriman Gallwey Score, menstrual diary endocrine parameters (serum total and free testosterone

progesterone
testosterone
fasting
inositol
folic acid
  • 42 views
  • 02 Jun, 2021
  • 1 location
ZEN-3694, Enzalutamide, and Pembrolizumab for the Treatment of Metastatic Castration-Resistant Prostate Cancer

block testosterone from reaching prostate cancer cells by binding to a receptor on prostate cancer cells, called androgen receptors. This works similar to a lock and key. When enzalutamide (key) inserts

  • 0 views
  • 13 Mar, 2022
  • 1 location