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Found 275 clinical trials
Apalutamide With or Without Stereotactic Body Radiation Therapy in Treating Participants With Castration-Resistant Prostate Cancer (PILLAR)

This phase II trial studies the how well apalutamide with or without stereotactic body radiation therapy work in treating participants with castration-resistant prostate cancer. Testosterone can

apalutamide
blood transfusion
gonadotropin
adenocarcinoma
androgens
  • 1 views
  • 08 Sep, 2021
  • 1 location
Improving Quality of Life of Prostate Cancer Survivors With Androgen Deficiency

The purpose of this phase II trial is to determine the efficacy and safety of testosterone replacement therapy (TRT) in improving the symptoms of androgen deficiency and health-related quality

prostatectomy
serum testosterone
androgens
testosterone
prostate specific antigen
  • 0 views
  • 13 Aug, 2021
  • 3 locations
Oxandrolone Rotator Cuff Trial

This study is about healing after a rotator cuff tear repair procedure. We hope to learn if a biologic medication: Oxandrolone, a synthetic derivative of the human hormone Testosterone (the

rotator cuff repair
full thickness rotator cuff tear
oxandrolone pill
  • 127 views
  • 23 Sep, 2021
  • 1 location
Reproductive Hormones During Sustained Administration of Kisspeptin

We want to find out what happens to reproductive hormone levels; Luteinising Hormone (LH), Follicle Stimulating Hormone (FSH), testosterone and oestradiol when kisspeptin is administered to

  • 134 views
  • 23 Jan, 2021
  • 1 location
Testing the Effects of Oxybutynin for the Treatment of Hot Flashes in Men Receiving Hormone Therapy for Prostate Cancer

. Androgen deprivation therapy decreases testosterone and other androgens through medications or surgical removal of the testicles. Relative to placebo, low- or high-dose oxybutynin may reduce hot flashes in

  • 0 views
  • 19 Jan, 2022
  • 69 locations
Relative Contributions of Predictors of Hyperandrogenism in Older vs. Young Women With PCOS

(PCOS) in a cross-sectional, physiological study. The investigators hypothesize that hyperinsulinemia is a stronger independent predictor of free testosterone (T) in older reproductive aged (vs. young

testosterone
luteinizing hormone
hyperandrogenism
testosterone level
gonadotropin
  • 335 views
  • 03 May, 2021
  • 1 location
Non-fucosylated Anti-CTLA-4 (BMS-986218) + Degarelix Acetate vs. Degarelix Acetate Alone in Men With High-risk Localized Prostate Cancer

The purpose of this study is to see whether immunotherapy with BMS-986218 added to degarelix (which suppresses testosterone) given prior to surgery can decrease the chance that cancer will come

  • 0 views
  • 04 Nov, 2021
  • 1 location
Androgen Blockade and Progesterone Augmentation of Gonadotropin Secretion

This study is trying to find out if flutamide (a medication that blocks the effects of testosterone) may help normalize an aspect of pituitary function (specifically, gonadotropin surge

  • 0 views
  • 28 Jan, 2021
  • 1 location
A Study of Apalutamide (Adjuvant Treatment) and Androgen Deprivation Therapy (ADT) in Participants Who Have Undergone Radical Prostatectomy (RP) for Non-metastatic Prostate Cancer and Who Are at High Risk for Metastases

biochemical recurrence (BCR) free rate. Sub-study: The purpose of the sub-study is to assess if the co administration of apalutamide and relugolix is able to maintain castrate levels of testosterone

prostatectomy
metastasis
apalutamide
androgens
adenocarcinoma
  • 17 views
  • 11 Jan, 2022
  • 37 locations
Trial of Rucaparib in Patients With Metastatic Hormone-Sensitive Prostate Cancer Harboring Germline DNA Repair Gene Mutations

example, prior to the start of medicines that lower testosterone level). It is unknown whether rucaparib will have the same benefit in men with metastatic prostate cancer carrying a mutation in a DNA

metastasis
platelet count
androgens
ct scan
adenocarcinoma
  • 162 views
  • 18 Apr, 2021
  • 2 locations