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Found 245 clinical trials
A Study of Selexipag as Add-On Treatment to Standard of Care in Children With Pulmonary Arterial Hypertension (SALTO)

The purpose of this study is to evaluate whether the addition of selexipag to standard of care treatment delays disease progression in children with Pulmonary Arterial Hypertension (PAH) in comparison to placebo.

endothelin receptor antagonist
endothelin
primary pulmonary hypertension
right heart catheterization
pulmonary arterial hypertension
  • 247 views
  • 25 Jul, 2022
  • 88 locations
Physiological-based Cord Clamping in Congenital Diaphragmatic Hernia (PinC)

Pulmonary hypertension is a major determinant of postnatal survival in infants with a congenital diaphragmatic hernia (CDH). The current care during the perinatal stabilisation period in infants born with this rare birth defect might contribute to the development of pulmonary hypertension after birth - in particular umbilical cord clamping before …

umbilical cord clamping
diaphragmatic hernia
congenital diaphragmatic hernia
resuscitation
hypertension
  • 0 views
  • 12 Jul, 2022
  • 5 locations
A Study Evaluating the Efficacy and Safety of Ralinepag to Improve Treatment Outcomes in PAH Patients

Study ROR-PH-301, ADVANCE OUTCOMES, is designed to assess the efficacy and safety of ralinepag when added to pulmonary arterial hypertension (PAH) standard of care or PAH-specific background therapy in subjects with World Health Organization (WHO) Group 1 PAH.

endothelin receptor antagonist
calcium
hypertension
beta blockers
digoxin
  • 6468 views
  • 05 Jul, 2022
  • 229 locations
A Study of Ralinepag to Evaluate Effects on Exercise Capacity by CPET in Subjects With WHO Group 1 PH (CAPACITY)

Study ROR-PH-302, ADVANCE CAPACITY, is designed to evaluate the effects of ralinepag therapy on exercise capacity as assessed by change in peak oxygen consumption (VO2) derived from cardiopulmonary exercise testing (CPET) after 28 weeks of treatment

endothelin receptor antagonist
endothelin
diuretics
cardiopulmonary exercise testing
ralinepag
  • 4 views
  • 21 Jul, 2022
  • 36 locations
A Study of Androgen Annihilation in High-Risk Biochemically Relapsed Prostate Cancer

This is a randomized, open-label, three-arm, phase 3 study in men with biochemically recurrent prostate cancer and PSA doubling time ≤ 9 months at the time of study entry.

growth factor
bone scan
metastasis
luteinizing hormone-releasing hormone agonist
testosterone
  • 498 views
  • 27 May, 2022
  • 56 locations
Letrozole in Stimulated IVF Cycles

In-vitro fertilization (IVF) is the treatment of choice for couples with prolonged infertility. The treatment usually involves hormonal stimulation of the ovaries by follicle stimulating hormone (FSH), followed by surgical removal of eggs which are then mixed with sperm in the laboratory to create embryos. The success rates of IVF …

androgens
estrogen
ovarian stimulation
clomiphene
follicle stimulating hormone
  • 395 views
  • 19 Apr, 2022
  • 2 locations
Antiandrogen Therapy and Radiation Therapy With or Without Docetaxel in Treating Patients With Prostate Cancer That Has Been Removed by Surgery

This randomized phase II/III trial studies docetaxel, antiandrogen therapy, and radiation therapy to see how well it works compared with antiandrogen therapy and radiation therapy alone in treating patients with prostate cancer that has been removed by surgery. Androgen can cause the growth of prostate cells. Antihormone therapy may lessen …

  • 1485 views
  • 27 Apr, 2022
  • 222 locations
Two Studies for Patients With High Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a High Gene Risk Score, The PREDICT-RT Trial

This phase III trial compares less intense hormone therapy and radiation therapy to usual hormone therapy and radiation therapy in treating patients with high risk prostate cancer and low gene risk score. This trial also compares more intense hormone therapy and radiation therapy to usual hormone therapy and radiation therapy …

  • 5 views
  • 27 Apr, 2022
  • 85 locations
DianaWeb: Before and After Study Online Based Participatory Research on Breast Cancer Women

DianaWeb is a community-based participatory research (CBPR) offered to Italian breast cancer patients. The aim of the study is the evaluation of effectiveness of a lifestyle and nutrition intervention to improve the prognosis. DianaWeb study utilizes an interactive website - http://www.dianaweb.org/ - to monitor patient life-style, and to obtain clinical, …

  • 0 views
  • 07 Oct, 2021
  • 1 location
Testosterone Replacement in Male Cancer Survivors With Fatigue and Low Testosterone

The overall goal of this study is to evaluate the effect of a testosterone drug called Depo-Testosterone (or 'testosterone cypionate'), an FDA-approved drug for improving fatigue, sexual

serum testosterone
testosterone level
solid tumors
deficiency
cancer
  • 107 views
  • 14 Mar, 2022
  • 1 location