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Found 247 clinical trials
Right Atrial Fibrosis in Pulmonary Hypertension

The study aim to assess right atrial (RA) remodeling, in terms of RA fibrosis, in pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension patients. This will be investigated in detail with in-depth cardiac magnet resonance imaging (CMRI). A cohort with exclusion of pulmonary hypertension which underwent CMRI due to dyspnoe …

right heart catheterization
pulmonary arterial hypertension
chronic thromboembolic pulmonary hypertension
Accepts healthy volunteers
  • 0 views
  • 17 Nov, 2021
  • 2 locations
Genetic and Environmental Determinants That Control Metabolism in Pulmonary Hypertension

The investigators are performing this research study to determine whether having low iron-sulfur cluster levels can cause a disease known as pulmonary hypertension (PH). PH is defined as abnormally high blood pressure in the arteries of the lungs. Usually, small specialized structures inside each human cell called mitochondria are in …

right heart catheterization
iron
  • 18 views
  • 25 May, 2022
  • 1 location
Natural History Study of Biomarkers in Pulmonary Arterial Hypertension

Background High blood pressure in the lungs, known as pulmonary arterial hypertension (PAH), is a rare disorder. Some people have disease-associated PAH and some have PAH from an unknown cause. Researchers want to follow the natural history of all PAH patients to understand how PAH progresses in order to discover …

left ventricular end-diastolic pressure
walk tests
hypertension
Accepts healthy volunteers
pulmonary arterial hypertension
  • 61 views
  • 20 Jul, 2022
  • 1 location
Opioid-Redox Study (ORS)

gonadotropin-stimulating hormone, resulting in reduced levels of luteinizing hormone. The result of these changes is reduced secretion of testosterone and estradiol what results in symptoms of hypogonadism

depression
oxycodone
opioid
nausea
opioid agonist
  • 80 views
  • 24 Feb, 2022
  • 1 location
Neuregulin-1 in Patient With Different Forms of Cardiovascular Diseases: a Pilot Study (NRG-1-CVDs)

This is an observational study of Neuregulin-1 (NRG-1) plasma levels in patients with different forms of cardiovascular disease including microvascular angina (MVA), heart failure with preserved ejection fraction (HFpEF), as well as, heart failure with reduced ejection fraction (HFrEF) and pulmonary hypertension (PH). Investigators intend to identify cardiovascular diseases which …

chest pain
depression
heart disease
Accepts healthy volunteers
heart failure
  • 0 views
  • 08 Aug, 2022
  • 1 location
Characteristics of Pulmonary Vascular Changes in Patients With Kidney Transplantation

The aim of the study is to investigate pulmonary hemodynamics at rest and during exercise in patients before and after kidney transplantation.

  • 0 views
  • 18 Apr, 2021
  • 1 location
Early Diagnosis of Pulmonary Hypertension in Patients With Inflammatory Rheumatic Connective Tissue Diseases

The purposes of this study are (I), to evaluate various screening methods for their ability to predict and to confirm Pulmonary Hypertension (PH) in scleroderma patients, and (II) to evaluate the incidence of PH (i.e. the number of new cases per year) in scleroderma patients.

rheumatism
pulmonary hypertension
vascular disease
connective tissue diseases
scleroderma
  • 2 views
  • 21 Jul, 2022
  • 1 location
Arrhythmias in Pulmonary Hypertension Assessed by Continuous Long-term Cardiac Monitoring (ASPIRE)

Arrhythmias are considered a prominent phenomenon in pulmonary hypertension (PH) as the disease progresses. According primarily to retrospective studies with up to 24 hours of monitoring, supraventricular tachycardias (SVT) can be found in 8-35% of patients, with significant impact on survival. Furthermore, a few prospective studies to date deploying short-term …

heart disease
cardiac monitoring
hypertension
right heart catheterization
pulmonary arterial hypertension
  • 0 views
  • 17 May, 2022
  • 1 location
New Orleans Pulmonary Hypertension Biobank (NO-PH Biobank)

Pulmonary hypertension (PH) is a serious condition characterized by a mean pulmonary artery pressure >=25mmHg on right heart catheterization (RHC). Despite advances in PH care, outcomes are still sub-optimal and further research is required into the pathobiology of the disease and development of biomarkers that can guide clinical care. The …

rheumatism
progressive systemic sclerosis
hypertension
right heart catheterization
mixed connective tissue disease
  • 114 views
  • 30 Jan, 2022
  • 1 location
Urethral Stricture After Transurethral Resection of the Prostate/Bladder: a Prospective Study of Risk Factors

There is currently no prognostic or predictive risk marker for this urethral stricture disease. The most conservative standard treatment for urethral stricture (internal urethrotomy) has a very high recurrence rate (greater than 75%) and, on many occasions, reconstructive urologists have to choose within a great variety of further complex interventions. …

  • 8 views
  • 19 Mar, 2021
  • 1 location