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Found 246 clinical trials
Phenotyping Study of CYP3A4 Activity in Patients With Prostate Cancer Versus Male Patients With Other Types of Solid Tumours With Midazolam

The hepatic enzyme, cytochrome P450 3A4 (CYP3A4) is important for the metabolism of many drugs including taxanes. Previous reported studies reported a decreases in docetaxel exposure in prostate cancer patients compared to patients with other solid tumours. The difference was 1.8-fold for intravenous administration and 2.8-fold for oral administration. The …

  • 0 views
  • 19 Sep, 2022
  • 1 location
A Phase 2 Open-Label Study to Evaluate the Efficacy and Safety of Ruxolitinib on Hair Regrowth in Patients With Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy (APECED)-Associated Alopecia Areata

Background Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED) is a problem of the immune system. In people with APECED, the immune system makes a mistake and attacks the body. Some people with APECED have a type of hair loss called alopecia areata (AA). No drugs are approved to treat AA. Objective …

Accepts healthy volunteers
cervical cap
areata alopecia
graft-versus-host disease
bilateral tubal ligation
  • 30 views
  • 20 Sep, 2022
  • 1 location
4D-flow Cardiac MRI to Assess Pulmonary Arterial Pressure in Pulmonary Hypertension

Due to radiation exposure and low but real risk of morbidity and mortality associated with right heart catheterization, non-invasive procedures to estimate mPAP are desired for the diagnosis of PH or to monitor treatment effectiveness. Echocardiography is used as a screening tool to estimate systolic pulmonary arterial pressure (sPAP), but …

pulmonary arterial pressure
right heart catheterization
  • 0 views
  • 19 Nov, 2021
  • 1 location
Can Dietary Phytoestrogens Slow Down Prostate Tumor Proliferation? (PRODICA)

The purpose of this study is to evaluate if a diet with a high content of phytoestrogens can slow down the prostate tumor proliferation. Phytoestrogens are found in food items such as soy, rye, and seeds. Two hundred thirty men with prostate cancer will be included in the study and …

prostatectomy
prostate tumor
  • 1 views
  • 15 Jun, 2022
  • 1 location
Transgender Men, Non-binary Persons and Testosterone Treatment BODY IDENTITY CLINIC

The aim of this study is to investigate transgender men and non-binary persons before and during testosterone treatment. The study will focus on: Cardiovascular status

Accepts healthy volunteers
  • 34 views
  • 28 Feb, 2022
  • 1 location
Correlation Between Seminal Vesicle Size and Duration of Sexual Abstinence (AbsVS)

poor prognostic factor. Some radiology centers recommend 3 days of sexual abstinence to allow a proper seminal vesicle study. Various factors, such as serum testosterone levels, autosomal dominant

  • 0 views
  • 23 Mar, 2022
  • 1 location
Evaluation of the Usefulness of Adopting Remote Mobile-based 6MWT Among Hospital Outpatients (the 6-APPnow) Within the Constraints Imposed by the SARS-COV2 Pandemic

The six-minute walk test (6MWT) is a standard method for measuring exercise capacity in patients with cardiopulmonary disease such as pulmonary hypertension (PAH) and measures how far a patient can walk in 6 minutes. The test is usually performed in the hospital, by walking along a hospital corridor. Since the …

Accepts healthy volunteers
walk tests
  • 6 views
  • 06 Nov, 2021
  • 1 location
Evaluation of a Causal Association Between Testosterone Levels, Dementia, and Adverse Mental Health Outcomes: A Mendelian Randomization Analysis

This study evaluates the association between testosterone levels and risk of dementia and adverse mental health outcomes (e.g. depression and anxiety). It is not known whether low testosterone

Accepts healthy volunteers
  • 0 views
  • 19 Sep, 2022
  • 1 location
Cross-sectional Study of 1200 Recreational Athletes With Former or Current Use of Androgenic Anabolic Steroids (FIDODK/BIC)

and more muscular appearance. Androgenic anabolic steroids (AAS) are the most frequently used PIED and include testosterone and its synthetic derivatives. However, PIEDs also include other hormones

cardiovascular disease
diabetes
  • 0 views
  • 03 May, 2022
  • 1 location
Precision-Based Genomics in Prostate Cancer

basis will be contacted every 6 months by phone or e-mail. They will be asked questions about their health. Data from their medical records will be collected. Participants will have testosterone

  • 0 views
  • 25 Jul, 2022
  • 1 location