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Found 267 clinical trials
PSCA-CAR T Cells in Treating Patients With PSCA+ Metastatic Castration Resistant Prostate Cancer

This phase I trial studies side effects and best dose of PSCA-chimeric antigen receptor (CAR) T cells in treating patients with prostate stem cell antigen positive (PSCA+) castration resistant prostate cancer that has spread to other places in the body (metastatic). PSCA-CAR T cells are immune cells that have been …

gilbert's syndrome
testosterone
ct scan
gonadotropin
orchiectomy
  • 3 views
  • 09 Feb, 2022
  • 1 location
Spironolactone Therapy In Young Women With NASH

primarily a feasibility-focused study, the investigators also aim to explore the pathways by which blocking testosterone receptors might alter the biologic processes that promote NASH and its associated

cirrhosis
fatty liver
testosterone
  • 37 views
  • 05 Mar, 2022
  • 1 location
Androgen Ablation Therapy With or Without Niraparib After Radiation Therapy for the Treatment of High-Risk Localized or Locally Advanced Prostate Cancer

is used as standard of care to lower testosterone levels in men with high risk localized or metastatic prostate cancer). Apa + ADT is the treatment combination of the drug apalutamide (Apa) given

  • 0 views
  • 15 Aug, 2021
  • 1 location
Suppression of Daytime and Nighttime Luteinizing Hormone Frequency by Progesterone

of being increased all the time). The purpose of this study is to see how quickly progesterone reduces LH pulses. The study is also meant to find out whether too much testosterone (also a hormone) in

estrogen
testosterone
follicle stimulating hormone
luteinizing hormone
gonadotropin
  • 61 views
  • 24 May, 2022
  • 1 location
The Effects of Castration on the Pharmacokinetics of Zolpidem After Single Dose Administration In Men With Prostate Cancer Undergoing Androgen Deprivation Therapy Compared to Normal Healthy Females

symptoms and medicines they are taking Male participants will have ADT as part of their standard cancer treatment. After that, the testosterone in their blood will be measured. They will repeat the

definitive treatment
androgen suppression
carcinoma
antiandrogen therapy
testosterone
  • 5 views
  • 25 May, 2022
  • 1 location
Enzalutamide With Venetoclax in Treating Patients With Metastatic Castration Resistant Prostate Cancer

This phase Ib/II trial studies the side effects and best dose of venetoclax when given together with enzalutamide and to see how well they work in treating patients with castration resistant prostate cancer that has spread to other places in the body. Androgens can cause the growth of prostate cancer …

testosterone
prostate specific antigen
potassium
bone disease
enzalutamide
  • 0 views
  • 15 May, 2022
  • 1 location
Efficacy Comparison of Tamoxifen and Tamoxifen With Antioxidants on Semen Quality of Male With Idiopathic Infertility

and serum testosterone will be done. 55 patients will be given tamoxifen alone ad 55 patients will be given tamoxifen with antioxidant. Then at the interval of 3 and 6 months after treatment , semen

Accepts healthy volunteers
  • 0 views
  • 25 Mar, 2022
Effects of Fasting Mimicking Diet (FMD) in Women With Polycystic Ovary Syndrome (PCOS)

alleviate its clinical manifestations and lower the related risk of T2DM and cardiovascular disease. Fasting-induced negative energy also potently affects the hormones such as estradiol, testosterone, and

testosterone
anovulation
oligomenorrhea
metabolic syndrome
diabetes
  • 7 views
  • 22 Mar, 2022
Impact of 11-oxygenated Androgens on Metabolic Dysfunction of Women With Polycystic Ovary Syndrome (11OXO-PCOS)

classic androgens (for example testosterone), and the less-characterised 11-oxygenated androgen subclass that arises from the adrenal glands. The investigators have recently demonstrated that 11

insulin resistance
testosterone
insulin
dehydroepiandrosterone
diabetes
  • 0 views
  • 22 Mar, 2022
Long-term Clinical Study of CN128 in Thalassemia Patients

> Safety evaluations include adverse events, adverse reactions, severe adverse events, and severe adverse reactions; growth; total and free testosterone in men, follicle-generating hormone and luteinizing

  • 2 views
  • 27 Jan, 2021
  • 1 location