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Found 267 clinical trials
Enzalutamide With or Without Radium Ra 223 Dichloride in Patients With Metastatic, Castration-Resistant Prostate Cancer

places in the body. Enzalutamide is an androgen receptor inhibitor that may slow down the growth of prostate cancer by blocking the action of the male hormone testosterone and other male hormones called

visceral metastases
cancer
bone metastases
biomarker analysis
androgen suppression
  • 1 views
  • 03 Mar, 2022
  • 2 locations
A Comparison of Aerobic and Resistance Exercise to Counteract Treatment Side Effects in Men With Prostate Cancer

androgen production as prostate cancer is dependent on testosterone and dihydrotestosterone for its growth.The side effects of ADT therapy are extensive and include changes in body composition (muscle loss

  • 0 views
  • 21 Dec, 2021
  • 1 location
Radium Ra 223 Dichloride, Hormone Therapy and Stereotactic Body Radiation Therapy in Treating Patients With Metastatic Prostate Cancer

fight prostate cancer by lowering the amount of testosterone the body makes. Stereotactic body radiation therapy is a specialized radiation therapy that sends x-rays directly to the tumor using smaller

cancer
MRI
metastatic prostate cancer
external beam radiation therapy
prostatectomy
  • 1 views
  • 02 Mar, 2022
  • 1 location
Menstrual Cycle MPS

Skeletal muscle size and function is regulated by various factors, including hormones. While we understand the role of male sex hormones (testosterone), we aren't sure how female sex hormones

Accepts healthy volunteers
  • 0 views
  • 12 May, 2022
  • 1 location
Docetaxel, Carboplatin, and Rucaparib Camsylate in Treating Patients With Metastatic Castration Resistant Prostate Cancer With Homologous Recombination DNA Repair Deficiency

prostate and resistant to testosterone suppression) with homologous recombination DNA repair deficiency. Chemotherapy drugs, such as docetaxel and carboplatin, work to stop the growth of cancer cells, by

orchiectomy
palb2
cancer
absolute neutrophil count
biomarker analysis
  • 28 views
  • 12 May, 2022
  • 1 location
Psma Intensity Can be Altered by Androgen and Phospho-SrC Obstruction (PICASSO)

combination with anti-testosterone drug call darolutamide. Who is it for? You may be eligible to join this study if you have metastatic prostate cancer and had a recent PSMA scan showing low PSMA

  • 0 views
  • 14 May, 2022
  • 1 location
Bipolar Androgen Therapy (BAT) and Radium-223 (RAD) in Metastatic Castration-resistant Prostate Cancer (mCRPC) (BAT-RAD)

patients will receive treatment with Radium-223 at a dose of 55 Kilobecquerel (kBq) per kilogram of body weight IV every 28 days, for 6 cycles, plus Testosterone Cypionate 400mg Intramuscular (IM) every 28

Accepts healthy volunteers
  • 0 views
  • 11 May, 2022
Testing the Safety of Different Doses of Olaparib Given Radium-223 for Men With Advanced Prostate Cancer With Bone Metastasis

This phase I/II trial studies the best dose and side effects of olaparib and how well it works with radium Ra 223 dichloride in treating patients with castration-resistant prostate cancer that has spread to the bone and other places in the body (metastatic). PARPs are proteins that help repair DNA …

orchiectomy
bone metastases
darolutamide
biomarker analysis
bone scan
  • 92 views
  • 24 May, 2022
  • 12 locations
Dissecting the IMpact of 11-OXygenated and Classic Androgens on Skeletal Muscle Insulin Sensitivity (DIMOXIS) (DIMOXIS)

Androgen excess is the cardinal biochemical feature of polycystic ovary syndrome (PCOS). Serum testosterone correlates with insulin resistance in PCOS, however, there is an urgent need to

dehydroepiandrosterone
insulin sensitivity
Accepts healthy volunteers
diabetes
androgens
  • 0 views
  • 10 May, 2022
  • 1 location
Abiraterone Acetate and Antiandrogen Therapy With or Without Cabazitaxel and Prednisone in Treating Patients With Metastatic, Castration-Resistant Prostate Cancer Previously Treated With Docetaxel

This randomized phase II trial studies how well abiraterone acetate and antiandrogen therapy, with or without cabazitaxel and prednisone, work in treating patients with castration-resistant prostate cancer previously treated with docetaxel that has spread to other parts of the body. Androgens can cause the growth of prostate cancer cells. Hormone …

orchiectomy
metastatic prostate cancer
biomarker analysis
bone scan
measurable disease
  • 1797 views
  • 21 Mar, 2022
  • 468 locations