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Found 11 clinical trials
Testosterone Therapy in Men With Low Testosterone Levels and Metabolic Syndrome or Early Stages of Type 2 Diabetes

Men with metabolic syndrome often have lower than normal testosterone levels and low testosterone levels have been suggested to predispose for development of type2 diabetes. The aim of the study is to evaluate if normalisation of serum testosterone levels in men with metabolic syndrome (Abdominal obesity, hypertension, dyslipidemia, insulin resistance …

type 2 diabetes mellitus
oral glucose tolerance test
insulin resistance
blood pressure diastolic
systolic blood pressure
  • 07 Nov, 2020
  • 1 location
Prostate Adenocarcinoma TransCutaneous Hormones

RATIONALE: The increasingly prolonged and extended use of androgen deprivation therapy (ADT) in the treatment of prostate cancer, usually achieved through the administration of LHRH agonists, has raised concerns about long-term toxicities, in particular osteoporosis and adverse metabolic changes which may be associated with type II diabetes and increased cardiovascular …

antiandrogen therapy
prostate cancer metastatic
metastatic prostate cancer
  • 27 Jan, 2021
  • 2 locations
Trial of Rucaparib in Patients With Metastatic Hormone-Sensitive Prostate Cancer Harboring Germline DNA Repair Gene Mutations

example, prior to the start of medicines that lower testosterone level). It is unknown whether rucaparib will have the same benefit in men with metastatic prostate cancer carrying a mutation in a DNA

platelet count
testosterone level
bone scan
antiandrogen therapy
  • 18 Apr, 2021
  • 2 locations
Perioperative Testosterone Replacement Therapy for the Improvement of Post-Operative Outcomes in Patients With Low Testosterone

. Information from this trial may be used to support the incorporation of testosterone level testing and testosterone replacement into the perioperative treatment decision-making process.

  • 01 Mar, 2021
  • 1 location
Efficacy and Safety of GnRH Analogue Triptorelin for HIV-1 Reservoir Reduction in ART Treated HIV-1 Infected Patients

the study without changes; unless there is rationale for change on medical ground. In order to prevent the negative effects of a low testosterone level, patients in the active group will be offered to

  • 29 Jan, 2021
  • 8 locations
Intermittent Androgen Deprivation Therapy for Stage IV Castration Sensitive Prostate Cancer

Adaptive Androgen Deprivation Therapy (ADT) plus Standard of Care. The purpose of this study is to develop adaptive therapy for high risk metastatic castration sensitive prostate cancer (mCSPC).

prostate adenocarcinoma
platelet count
antiandrogen therapy
  • 25 Apr, 2021
  • 1 location
Starting a Testosterone and Exercise Program After Hip Injury

This study is a randomized controlled double-blinded multi-center clinical trial enrolling female hip fracture patients who are 65 and older. It will compare the effects of six months of supervised exercise training combined with daily topical testosterone gel, to six months of supervised exercise and inactive gel, and to Enhanced …

topical testosterone
testosterone gel
subtrochanteric fracture
hip fracture
  • 25 Jan, 2021
  • 8 locations
Swiss Austrian German Testicular Cancer Cohort Study - SAG TCCS

The majority of testicular cancer patients can be cured with cisplatin-based chemotherapy. Mortality has been reduced even more within the last 15 years due to the stringent application of standard chemotherapy followed by resection of residual disease. This is a positive development considering that testicular cancer usually affects young men. …

cardiovascular disease
renal function tests
  • 23 Jan, 2021
  • 1 location
Evaluation of Association Between Testosterone Levels Dementia and Adverse Mental Health Outcomes

This study evaluates the association between testosterone levels and risk of dementia and adverse mental health outcomes (e.g. depression and anxiety). It is not known whether low testosterone levels may be associated with an increased risk of dementia. Learning about the association between testosterone levels and risk of dementia may …

  • 17 Feb, 2021
  • 1 location
Comparison Between Calculated Bioavailable Testosterone Level With Radio-immunoassay Result.

Currently, the gold standard to obtain bioavailable testosterone results is radioimmunoassay (RIA). However, this assay requires specific equipment. Giton in 2006 proposed an optimized calculation of the Vermeulen equation, the results of which seem to be well correlated with those obtained by RIA. The aim of this study is to …

  • 25 Mar, 2021
  • 1 location