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Found 79 clinical trials
Treatment of Radiation and Cisplatin Induced Toxicities With Tempol

A 10 week trial to assess the ability of Tempol to prevent and/or reduce toxicities associated with cisplatin and radiation treatment in head and neck cancer patients. Over the course of the 10 week trial, mucositis, nephrotoxicity, and ototoxicity will be monitored and assessed.

squamous cell carcinoma
squamous cell carcinoma of the head and neck
neck cancer
tempol
neutrophil count
  • 6 views
  • 23 Jan, 2021
  • 4 locations
Study of Dose Escalation of Abiraterone Actetate in Prostate Cancer

The purpose of this study is to test whether a dose escalation up to 2000 mg per day of abiraterone acetate is feasible and lead to disease stabilization in castration-resistant metastatic prostate cancer patients who experience disease progression within the first 6 months of abiraterone actetate at standard dose (1000 …

progressive disease
adenocarcinoma of prostate
abiraterone
ct scan
metastasis
  • 6 views
  • 25 Jan, 2021
  • 1 location
Prospective Controlled Randomized Multicentric Study on the Management of the Vesical Catheter in Colon Surgery.

INTRODUCTION: Recommendations for peroperative bladder catheterization remain a controversial issue since it is a procedure that is not without complications. Most of the current suggestions derive from open surgery data that have been extrapolated to Enhanced Recovery After Surgery (ERAS) or Fast-Track programs ranging between 24-48 hours. The objective of …

enhanced recovery after surgery
open surgery
colon operation
  • 0 views
  • 24 Jan, 2021
  • 1 location
Dose Escalation Study of Immunomodulatory Nanoparticles

PRECIOUS-01 is an immunomodulating agent composed of the invariant natural killer T cell (iNKT) activator threitolceramide-6 (ThrCer6, IMM60) and the New York Esophageal Squamous Cell Carcinoma-1 (NY-ESO-1) cancer-testis antigen peptides encapsulated in a poly(lactic-co-glycolic acid) (PLGA) nanoparticle. PRECIOUS-01 is being developed for the treatment of patients with NY-ESO-1-positive cancers.

  • 0 views
  • 18 Feb, 2021
  • 1 location
Impact of Exposure to Environmental Pollutants on Birth Outcomes in an Israeli Cohort

Objectives and hypothesis The scale and diversity of chemicals in worldwide use today is vast. Many of these chemicals are released into the environment where they are found in air, water, soil, house dust, and in the food supply, resulting in exposure to humans. Characterizing the extent of exposure and …

  • 1 views
  • 21 Jan, 2021
  • 2 locations
Impact of Immunotherapy on the Sperm Count of Patients With Cancer

Cancer is a public health problem. In recent years, oncology has been revolutionized with the advent of new treatments for different tumor models, mainly immunotherapy directed against cell cycle control points. Numerous inhibitory pathways are incorporated into the immune system to maintain tolerance and homeostasis, and these are collectively known …

  • 0 views
  • 25 Jan, 2021
  • 1 location
Swiss Austrian German Testicular Cancer Cohort Study - SAG TCCS

The majority of testicular cancer patients can be cured with cisplatin-based chemotherapy. Mortality has been reduced even more within the last 15 years due to the stringent application of

cardiovascular disease
seminoma
metastasis
renal function tests
  • 64 views
  • 23 Jan, 2021
  • 1 location
Toxicity Attributed to Genetic Polymorphisms in Testicular Germ Cell Tumor Survivors

The purpose of this study is to identify genetic variations in survivors of testicular cancer and connect these variations to differences in risks of late effects.

germ cell cancer
cancer
testicular
  • 18 views
  • 24 Jan, 2021
  • 1 location
Testicular Growth During Puberty in Boys With and Without a Left-sided Varicocele

testicular growth could predict the outcome of boys with a varicocele. During this study, testicular growth in boys with and without a left-sided varicocele will be examined in different schools using

  • 6 views
  • 23 Jan, 2021
A Study of miRNA 371 in Patients With Germ Cell Tumors

This trial studies whether the blood marker micro ribonucleic acid (miRNA) 371 can predict the chance of cancer returning in patients with germ cell cancers. Studying samples of blood from patients with germ cell cancers in the laboratory may help doctors predict how likely the cancer will come back.

human chorionic gonadotropin
gonadotropin
alpha fetoprotein
tumor markers
germ cell cancer
  • 0 views
  • 07 May, 2021
  • 346 locations