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Found 81 clinical trials
Prospective Exploratory Study of FAPi PET/CT With Histopathology Validation in Patients With Various Cancers

This exploratory study investigates how an imaging technique called 68Ga-FAPi-46 PET/CT can determine where and to which degree the FAPI tracer (68Ga-FAPi-46) accumulates in normal and cancer tissues in patients with cancer. Because some cancers take up 68Ga-FAPi-46 it can be seen with PET. FAP stands for Fibroblast Activation Protein. …

hematologic malignancy
pet/ct scan
positron emission tomography
pet scan
metastasis
  • 0 views
  • 26 Jan, 2021
  • 1 location
Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

This phase II trial studies how well cabozantinib works in combination with nivolumab and ipilimumab in treating patients with rare genitourinary (GU) tumors that have spread to other places in the body. Cabozantinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. …

pet scan
metastasis
nivolumab
karnofsky performance status
ct scan
  • 191 views
  • 07 Mar, 2021
  • 459 locations
Lenalidomide and Combination Chemotherapy (DA-EPOCH-R) in Treating Patients With MYC-Associated B-Cell Lymphomas

This phase I/II trial studies the side effects and best dose of lenalidomide when given together with combination chemotherapy and to see how well they work in treating patients with v-myc myelocytomatosis viral oncogene homolog (avian) (MYC)-associated B-cell lymphomas. Lenalidomide may stop the growth of B-cell lymphomas by blocking the …

low molecular weight heparin
doxorubicin
v-myc myelocytomatosis viral oncogene homolog
biological therapies
measurable disease
  • 81 views
  • 23 Jan, 2021
  • 3 locations
TESTO: Testosterone Effects on Short-Term Outcomes in Infants With XXY

This research study in infant males with Klinefelter syndrome (47,XXY) will learn more about the effect of testosterone on early health and development. The study is a total of three visits over 6 months with assessments of motor skills, body composition (muscle and fat), and hormone levels. This is a …

klinefelter syndrome
amniocentesis
post-natal
testosterone
testosterone level
  • 156 views
  • 23 Jan, 2021
  • 1 location
Clinical Trial of Oral Ciprofloxacin and Etoposide in Subjects With Resistant Acute Myeloid Leukemia (AML)(UF-AML-CE-101)

The purpose of the first part of this study is to establish the maximum tolerated dose (MTD) of oral ciprofloxacin when given in combination with a fixed dose of oral etoposide in patients with resistant acute myeloid leukemia (AML). The purpose of the second part of this study is to …

refractory acute myeloid leukemia (aml)
myeloid leukemia
etoposide
remission
induction chemotherapy
  • 13 views
  • 25 Jan, 2021
  • 1 location
Ibrutinib + R-CHOP Followed by Ibrutinib Maintenance

This is a prospective, multicenter, single arm, phase II trial in patients with 18 and <80 years with poor-prognosis (IPI 2) and newly diagnosed ABC-DLBCL. Aim of the study is to assess the efficacy and the safety of R-CHOP in combination with ibrutinib for 6 cycles followed by ibrutinib maintenance …

gilbert's syndrome
cancer
ibrutinib
measurable disease
growth factor
  • 0 views
  • 27 Jan, 2021
  • 49 locations
A Comparison of Side Effects in Hypogonadal Men Treated With Natesto Versus Testosterone Injections

The purpose of this study is to evaluate changes in vascular parameters and the prevalence of side effects in subjects receiving 1 cc (200mg) every 2 weeks intramuscular (IM) of Testosterone Cypionate versus subjects receiving 11mg three times daily (TID) Natesto to participant with clinical hypogonadism.

androgens
natesto
testosterone cypionate 200 mg/ml
testosterone
hypogonadotropic hypogonadism
  • 0 views
  • 24 Jan, 2021
TAA6 Cell Injection In The Treatment of Patients With Relapsed / Refractory Acute Myeloid Leukemia

This is a clinical study of TAA6 cell injection in the treatment of patients with relapsed / refractory Acute Myeloid Leukemia . The purpose is to evaluate the safety and effectiveness of CD276 targeted autologous chimeric antigen receptor T cells infusion in patients with relapsed / refractory CD276 positive Acute …

  • 0 views
  • 31 Jan, 2021
  • 1 location
Modified BFM-95 Regimen as First-Line Chemotherapy in Adults With T- Lymphoblastic Lymphoma

This study evaluates the efficacy and tolerability of treatment for T-lymphoblastic lymphoma (T-LBL) according to modified BFM-95 regimen for acute lymphoblastic leukemia.

lymphoma
lymphoblastic lymphoma
lymphoid leukemia
  • 25 views
  • 25 Jan, 2021
  • 1 location
Hypogonadotropic Hypogonadism in Obese Young Males

Obesity can lead to low testosterone concentrations in young men. This study will study the effects of low testosterone in those men and the result of treating them with clomiphene.

secondary hypogonadism
klinefelter syndrome
clomiphene
testosterone
testosterone level
  • 63 views
  • 26 Jan, 2021
  • 1 location