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Found 81 clinical trials
Trial to Evaluate Progression Free Survival With Primary Retroperitoneal Lymph-node Dissection (pRPLND) Only in Patients With Seminomatous Testicular Germ Cell Tumors With Clinical Stage IIA/B (PRIMETEST)

Primary objective: to evaluate progression-free survival in patients with clinical stage II A/B seminomatous germ cell tumor undergoing primary retroperitoneal lymph node dissection (RPLND) without adjuvant treatment Secondary objectives: overall survival perioperative complications (Clavien-Dindo score) quality of life (EORTC QLQ C30, EORTC QLQ TC26) long term sequelae rate of retrograde …

  • 3 views
  • 21 Jan, 2021
  • 1 location
Prospective Two-arm Study of Fertility in Men With COVID-19

-2 on fertility and determining if viral bodies are capable of directly damaging testicular cells

  • 0 views
  • 27 Jan, 2021
  • 1 location
Surgery Without Neoadjuvant Chemoradiotherapy Compared With Neoadjuvant Chemoradiotherapy for Rectal Cancer With Negative Circumferential Resection Margin Based on MRI Assessment a Perspective Multicenter Randomized Controlled Trial

complications, anastomotic leakage, anastomotic stenosis, sexual dysfunction, testicular or ovary failure. Patients undergoing resection for rectal cancer had low rates of local recurrence and long disease-free

  • 4 views
  • 19 Feb, 2021
  • 1 location
Living After a Rare Cancer of the Ovary: Chronic Fatigue Quality of Life and Late Effects of Chemotherapy

While they are documented in patients in remission of testicular cancer, the sequelae of chemotherapy and the impact of the disease and its treatments on the living conditions and QoL of women

testicular
cancer
cancer chemotherapy
carcinoma
  • 18 views
  • 26 Jan, 2021
  • 29 locations
One Stage vs. Two Stage Gubernaculum Sparing Laparoscopic Orchidopexy (GSLO)

patient important outcome: testicular atrophy.

  • 10 views
  • 26 Jan, 2021
  • 1 location
A Study Evaluating the Effects of Lipid Lowering Treatment on Steroid Synthesis

Cholesterol is the precursor of glucocorticoids, mineralocorticoids and sex steroids. Both adrenal and non-adrenal (ovarian + testicular) all steroid hormones are primarily synthesized

ezetimibe
atorvastatin
  • 4 views
  • 07 Nov, 2020
  • 1 location
A Study of CA-4948 in Patients With Relapsed or Refractory Hematologic Malignancies

extranodal subtypes: Leg-, testicular-, or not otherwise specified (NOS)-type Cohort 3 - Primary central nervous system lymphoma (PCNSL) Cohort 4 - Patients receiving ibrutinib monotherapy

  • 15 views
  • 25 Jan, 2021
  • 10 locations
Development of Diagnostics and Treatment of Urological Cancers

The purpose of the study is to evaluate whether state-of-the-art technologies such and next generation sequencing and drug sensitivity and resistance testing of patient derived tumour tissue can facilitate research translation and improve outcome of urologic cancers.

cancer
urinary tract cancer
  • 12 views
  • 17 Feb, 2021
  • 1 location
Detection of SARS-CoV-2 in Follicular Fluid and Cumulus-oocyte-complexes in COVID-19 Patients

has been shown in testicular, uterine and placental cells. Based on available transcriptomic data, co-expression of ACE2 and TMPRSS2 is also seen on oocyte level, but the possible impact on

SARS
intracytoplasmic sperm injection
target cells
oocyte retrieval
covid-19
  • 109 views
  • 25 Jan, 2021
  • 1 location
A Phase 1/2 Study of In Situ Vaccination With Tremelimumab and IV Durvalumab Plus PolyICLC in Subjects With Advanced Measurable Biopsy-accessible Cancers

This is an open-label, multicenter Phase 1/2 study of the CTLA-4 antibody, tremelimumab, and the PD-L1 antibody, durvalumab (MEDI4736), in combination with the tumor microenvironment (TME) modulator polyICLC, a TLR3 agonist, in subjects with advanced, measurable, biopsy-accessible cancers.

tremelimumab
breast cancer
cytotoxic t-lymphocyte antigen 4
vaccination
durvalumab
  • 0 views
  • 03 Mar, 2021
  • 7 locations