Found 79 clinical trials
Diagnostic Yield of Colonoscopy Surveillance in Testicular Cancer Survivors Treated With Platinum-based Chemotherapy
Testicular cancer (TC) survivors treated with platinum-based chemotherapy have an increased risk of colorectal cancer (CRC) (hazard ratio (HR) 3.9 for platinum-containing chemotherapy versus no
- 2 views
- 23 Jan, 2021
- 4 locations
Fresh Vs Frozen Surgical Sperm in IVF
The primary objective of this study is to determine if the use of frozen surgical testicular sperm specimens for ICSI lead to different IVF outcomes when compared with the use of fresh surgical
- 38 views
- 29 May, 2021
- 1 location
Fertility in Young Adults Who Did (Not) Store Testicular Tissue Before a Treatment Leading to Fertility Problems.
testicular tissue at a young age. These young adults will be invited by e-mail/letter/telephone to evaluate their fertility status (Tanner stage, testicular volume, hormones, semen analysis) at adult age and
- 2 views
- 01 Feb, 2021
- 1 location
Reduced Intensity Radio-chemotherapy for Stage IIA/B Seminoma
The trial investigates a stage-adapted (stage IIA or IIB) de-escalation of the standard treatments in the context of a multimodality treatment with chemo- and radiotherapy in seminoma patients. The goal is to safely de-escalate treatment while maintaining/enhancing efficacy, which is not a standard practice yet.
- 14 views
- 04 Mar, 2021
- 17 locations
Trial to Evaluate Progression Free Survival With Primary Retroperitoneal Lymph-node Dissection (pRPLND) Only in Patients With Seminomatous Testicular Germ Cell Tumors With Clinical Stage IIA/B (PRIMETEST)
Primary objective: to evaluate progression-free survival in patients with clinical stage II A/B seminomatous germ cell tumor undergoing primary retroperitoneal lymph node dissection (RPLND) without adjuvant treatment Secondary objectives: overall survival perioperative complications (Clavien-Dindo score) quality of life (EORTC QLQ C30, EORTC QLQ TC26) long term sequelae rate of retrograde …
- 3 views
- 21 Jan, 2021
- 1 location
One Stage vs. Two Stage Gubernaculum Sparing Laparoscopic Orchidopexy (GSLO)
patient important outcome: testicular atrophy.
- 10 views
- 26 Jan, 2021
- 1 location
Surgery Without Neoadjuvant Chemoradiotherapy Compared With Neoadjuvant Chemoradiotherapy for Rectal Cancer With Negative Circumferential Resection Margin Based on MRI Assessment a Perspective Multicenter Randomized Controlled Trial
complications, anastomotic leakage, anastomotic stenosis, sexual dysfunction, testicular or ovary failure. Patients undergoing resection for rectal cancer had low rates of local recurrence and long disease-free
- 4 views
- 19 Feb, 2021
- 1 location
A Study Evaluating the Effects of Lipid Lowering Treatment on Steroid Synthesis
Cholesterol is the precursor of glucocorticoids, mineralocorticoids and sex steroids. Both adrenal and non-adrenal (ovarian + testicular) all steroid hormones are primarily synthesized
- 4 views
- 07 Nov, 2020
- 1 location
A Study of CA-4948 in Patients With Relapsed or Refractory Hematologic Malignancies
extranodal subtypes: Leg-, testicular-, or not otherwise specified (NOS)-type Cohort 3 - Primary central nervous system lymphoma (PCNSL) Cohort 4 - Patients receiving ibrutinib monotherapy
- 15 views
- 12 May, 2021
- 11 locations
Development of Diagnostics and Treatment of Urological Cancers
The purpose of the study is to evaluate whether state-of-the-art technologies such and next generation sequencing and drug sensitivity and resistance testing of patient derived tumour tissue can facilitate research translation and improve outcome of urologic cancers.
- 12 views
- 17 Feb, 2021
- 1 location