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Found 81 clinical trials
Spermatogonial Stem Cell (SSC) Transplant and Testicular Tissue Grafting

Spermatogonial stem cell transplantation through ultrasound guided rete testis injection and testicular tissue grafting will be performed for participants who have frozen testicular tissue prior

testicular
anesthesia
  • 72 views
  • 15 Feb, 2021
  • 1 location
Whole Body MRI With DWI for Monitoring Patients Treated for Testicular Cancer Stage II-III

Testicular cancer (TC) affects approx. 1% of Danish men and is the most common cancer in men aged 15-35 years. It is the most curable solid cancer type with a 5-year survival rate of 90-95

metastasis
  • 9 views
  • 25 Jan, 2021
  • 1 location
Adjuvant Bleomycin Etoposide and Cisplatin (BEP) Versus Carboplatin in Stage I Seminomatous Testicular Cancer

One course of adjuvant carboplatin AUC7 is considered internationally to be a standard treatment option in clinical stage I seminoma, regardless of risk factors. Treatment is based on a large, randomized phase III study comparing adjuvant carboplatin with adjuvant radiotherapy. This study was done without registering data on possible risk …

alpha fetoprotein
cancer chemotherapy
orchiectomy
etoposide
seminoma
  • 15 views
  • 26 Jan, 2021
  • 2 locations
Male Fertility Preservation Using Cryopreservation of Testicular Tissue Before Highly Gonadotoxic Cancer Treatment

offered to all pubertal male patients. For prepubertal boys, only the experimental option of testicular biopsy in order to cryopreserve testicular stem cells can be proposed. Primary aims

fertility preservation
cancer treatment
  • 40 views
  • 24 Jan, 2021
  • 3 locations
Senescence and the Early Ageing Phenotype After Chemotherapy for Testicular Cancer: the SEA-CAT Study

Cisplatin-combination chemotherapy causes inevitably DNA damage by platinum-DNA adduct formation of both tumor cells but also healthy cells. It therefore stands to reason that testicular cancer

combination chemotherapy
dna damage
dna adduct formation
  • 1 views
  • 25 Jan, 2021
  • 1 location
Diagnostic Yield of Colonoscopy Surveillance in Testicular Cancer Survivors Treated With Platinum-based Chemotherapy

Testicular cancer (TC) survivors treated with platinum-based chemotherapy have an increased risk of colorectal cancer (CRC) (hazard ratio (HR) 3.9 for platinum-containing chemotherapy versus no

  • 2 views
  • 23 Jan, 2021
  • 4 locations
Laser Assisted Sperm Selection of Viable Immotile Testicular Sperm in Azoospermic Infertile Men

This study aims to investigate the outcome of ICSI after using LAISS for selection of viable immotile testicular sperm in azoospermic infertile men. Patients will be randomly assigned to

  • 0 views
  • 28 Jan, 2021
  • 2 locations
Fresh Vs Frozen Surgical Sperm in IVF

The primary objective of this study is to determine if the use of frozen surgical testicular sperm specimens for ICSI lead to different IVF outcomes when compared with the use of fresh surgical

antral follicle count
intracytoplasmic sperm injection
follicle stimulating hormone
anti-mullerian hormone
single embryo transfers
  • 38 views
  • 23 Jan, 2021
Fertility in Young Adults Who Did (Not) Store Testicular Tissue Before a Treatment Leading to Fertility Problems.

testicular tissue at a young age. These young adults will be invited by e-mail/letter/telephone to evaluate their fertility status (Tanner stage, testicular volume, hormones, semen analysis) at adult age and

semen analysis
  • 2 views
  • 01 Feb, 2021
  • 1 location
Reduced Intensity Radio-chemotherapy for Stage IIA/B Seminoma

The trial investigates a stage-adapted (stage IIA or IIB) de-escalation of the standard treatments in the context of a multimodality treatment with chemo- and radiotherapy in seminoma patients. The goal is to safely de-escalate treatment while maintaining/enhancing efficacy, which is not a standard practice yet.

cisplatin etoposide
orchiectomy
etoposide
seminoma
fdg-pet
  • 14 views
  • 04 Mar, 2021
  • 17 locations