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Found 126 clinical trials
Switching From Protease Inhibitor/Ritonavir to Generic Single Tablet Regimen of Tenofovir Alafenamide/Emtricitibine/Dolutegravir

This is a phase III, multicenter, open-label, single-arm study of 190 virologically suppressed HIV-infected adults

HIV Vaccine
dolutegravir
integrase inhibitors
hiv-1 infection
hysterectomy
  • 0 views
  • 26 Jan, 2021
  • 2 locations
Tenofovir Alafenamide Versus Entecavir for the Treatment of Chronic Hepatitis B

To compare the efficacy and renal safety of tenofovir alafenamide (TAF) versus entecavir (ETV) in the chronic hepatitis B patients.

antiviral agents
entecavir
antiviral therapy
tenofovir
hepatitis
  • 15 views
  • 26 Jan, 2021
  • 1 location
Tenofovir Disoproxil Fumarate in Combination of Hepatitis B Vaccine for Preventing Hepatitis B Vertical Transmission

HBV DNA > 200,000 IU/mL is the major independent risk for mother-to-child transmission (MTCT). A recent randomized controlled trial has shown that Tenofovir Disoproxil Fumarate (TDF) use during the

hbv dna
tenofovir
hepatitis
mother-to-child transmission
hepatitis b immune globulin
  • 81 views
  • 23 Jan, 2021
  • 9 locations
Tenofovir-lamivudine-dolutegravir Combination as Second-line ART: a Randomised Controlled Trial

monitored, has a high barrier to resistance, and that is low cost. The fixed-dose combination of tenofovir-lamivudine-dolutegravir offers significant advantage as a potential second-line regimen compared to

HIV Vaccine
efavirenz
antiretroviral agents
dolutegravir
tenofovir
  • 61 views
  • 25 Jan, 2021
  • 2 locations
Bictegravir/Emtricitabine/Tenofovir Alafenamide (B/F/TAF) in HIV-1 Infected Patients With Active Illicit Substance usE

This study will evaluate the efficacy and safety of bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF) in HIV-1 infected patients who actively use illicit substances. The study will also

  • 5 views
  • 23 Jan, 2021
  • 1 location
Impact of Weekly Administration of Rifapentine and Isoniazid on Steady State Pharmacokinetics of Tenofovir Alafenamide in Healthy Volunteers (YODA)

Background Human immunodeficiency virus (HIV) is treated with antiretroviral drugs. Many people with HIV also have the lung infection tuberculosis (TB). Most TB treatments are complicated. A simpler treatment of two TB drugs can be taken once a week. Researchers want to study how the HIV and TB drugs affect …

cervical cap
vitamins
fasting
blood test
  • 9 views
  • 25 Jan, 2021
  • 1 location
Assessment of Drug-drug Interactions Between Masculinizing Hormone Therapy and Antiretroviral Agents Concomitantly for Pre-exposure Prophylaxis Among Transgender Men

could lead to concerns and subsequent prioritizing MHT over PrEP among TGM. Because tenofovir alafenamide (TAF) can achieve higher intracellular tenofovir diphosphate (TFV-DP) levels with lower

  • 0 views
  • 26 Jan, 2021
  • 1 location
The Efficacy and Safety of TAF vs Other NAs in Patients With LVL

weeks of treatment with the first-line drugs, entecavir or tenofovir disoproxil fumarate, a certain proportion of patients still had low levels of HBV replication. Tenofovir alafenamide fumarate is a

cancer
entecavir
tenofovir
hepatitis
liver disease
  • 0 views
  • 25 Jan, 2021
  • 1 location
Testing the Safety and Efficacy of Commercial Drug Biktarvy in Subjects Known to Have the 184 Resistance Mutation to a Component in Biktarvy

An Open-Label Study to Evaluate Switching from a Regimen of Elvitegravir/Tenofovir alafenamide/Emtricitabine/Cobicistat and Darunavir, to a Fixed-Dose Combination of Bictegravir/Tenofovir

  • 8 views
  • 25 Jan, 2021
  • 1 location
Assessment of Drug-drug Interactions Between Feminizing Hormone Therapy and Emtricitabine/Tenofovir Alafenamide Concomitantly for Pre-exposure Prophylaxis Among Transgender Women

Recent studies have showed that there were significant drug-drug interactions (DDI) from feminizing hormone therapy (FHT) towards emtricitabine/tenofovir disoproxil fumarate (F/TDF)-based pre

  • 0 views
  • 25 Jan, 2021
  • 1 location