tenofovir Clinical Research Trials

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Found 126 clinical trials

Tenofovir Rectal Douche to Prevent HIV Transmission

DREAM-03 is an early phase-1, open label study to compare the safety, pharmacokinetics (PK), pharmacodynamics (PD), and acceptability of 3 sequences of tenofovir (TFV) and non-medicated douches

pre-exposure prophylaxis (prep)

sexually transmitted disease

fumarate

oophorectomy

hiv pre-exposure prophylaxis

1 views
26 Jan, 2021
2 locations

Tenofovir Alafenamide in HBV Related Decompensated Liver

TAF is a new prodrug of tenofovir, specifically designed to achieve higher intracellular active drug concentration allowing for dosing of only 25 mg once daily and thus can potentially lower the

0 views
27 Jan, 2021
1 location

Adjuvant Entecavir or Tenofovir for Postoperative HBV-HCC

This study aims to compare the effect of antiviral therapy with entecavir or tenofovir for hepatitis B virus-related hepatocellular carcinoma after radical hepatectomy. Included patients will

hepatectomy

hepatitis b surface antigen

antiviral drugs

lamivudine

hepatitis

4 views
14 Feb, 2021
1 location

Switching From Tenofovir Disoproxil Fumarate to Besifovir Dipivoxil Maleate

A research study to observe the safety, efficacy and tolerability of switching from Tenofovir Disoproxil Fumarate to Besifovir dipivoxil maleate in patients with chronic hepatitis B

fumarate

hepatitis b antigen

hepatitis

tenofovir

1 views
24 Jan, 2021
1 location

Switch to Bictegravir/Emtricitabine/Tenofovir Alafenamide After Renal Transplant

This is an open-label study, where participants will be switched from their current HIV medication to the study drug, Biktarvy. Open-label means both the investigator and the participant will know what drug will be given. Participants will be followed for 48 weeks in order to monitor the efficacy, safety and …

HIV Vaccine

bictegravir/emtricitabine/tenofovir

kidney transplant

immunodeficiency

biktarvy

0 views
27 Jan, 2021

Efficacy of Addition of Fecal Microbiota Transplant (FMT) and Plasma Exchange to Tenofovir in Comparison to Monotherapy With Tenofovir in ACLF-HBV

A randomized controlled trial to study the efficacy of addition of FMT & plasma exchange to tenofovir compared to monotherapy with tenofovir in patients with HBV reactivation who develops

acute on chronic liver failure

hepatic failure

plasma exchange

tenofovir

0 views
25 Jan, 2021
1 location

Tenofovir in Pregnancy to Prevent Mother to Child Transmission of Hepatitis B.

. Antiretrovirals, like tenofovir (TFV) that is administered as the prodrug Tenofovir Disoproxil Fumarate (TDF), are active against HBV and may reduce the risk of HBV transmission at birth if offered at the right

hepatocellular carcinoma

fumarate

HIV Infection

hepatitis b antigen

antiretroviral agent

0 views
26 Jan, 2021
1 location

Tenofovir Disoproxil Fumarate in Combination of Hepatitis B Vaccine for Preventing Hepatitis B Vertical Transmission

HBV DNA > 200,000 IU/mL is the major independent risk for mother-to-child transmission (MTCT). A recent randomized controlled trial has shown that Tenofovir Disoproxil Fumarate (TDF) use during the

hbv dna

fumarate

mother-to-child transmission

tenofovir

hepatitis b immune globulin

81 views
23 Jan, 2021
9 locations

Tenofovir Alafenamide Versus Entecavir for the Treatment of Chronic Hepatitis B

To compare the efficacy and renal safety of tenofovir alafenamide (TAF) versus entecavir (ETV) in the chronic hepatitis B patients.

antiviral agents

tenofovir

entecavir

hepatitis

antiviral therapy

15 views
26 Jan, 2021
1 location

Safety and Pharmacokinetic Study of Tenofovir Alafenamide (TAF)/Elvitegravir (EVC) Administered Rectally

The purpose of this study is to evaluate the safety and pharmacokinetics of rectal administration of a tenofovir alafenamide (TAF)/elvitegravir (EVG) insert at two dose levels in HIV-uninfected

HIV Vaccine

hiv test

elvitegravir

tenofovir

0 views
24 Jan, 2021
2 locations

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Found 126 clinical trials