Found 126 clinical trials
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Accepting pediatric ages
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Accepting Seniors
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Simplifying Treatment and Monitoring for HIV (STREAM HIV)
This study seeks to determine the clinical efficacy and cost effectiveness of implementing an integrated model for HIV monitoring using point of care (POC) tenofovir (TFV) adherence testing and
- 0 views
- 16 Feb, 2021
- 1 location
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Phase 4 trial
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Accepting Seniors
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Accepting adults
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1000s of participants
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An interventional trial
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For all genders
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Hepatology (Liver, Pancreatic, Gall Bladder)
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Currently Recruiting
Change of Renal Function and Bone Mineral Density in CHB Patients Switch From TDF to TAF vs. Maintaining TDF
In Chronic hepatitis B (CHB) patients receiving long-term sequential Neucleos(t)ides(NAs), majority of these CHB patients experienced drug resistance and switched to Tenofovir disoproxil
- 45 views
- 25 Jan, 2021
- 1 location
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Multi-country trial
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Phase 3 trial
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Accepting adults
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1000s of participants
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An interventional trial
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For females only
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Pediatrics/Neonatology
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Currently Recruiting
Evaluating the Safety and Efficacy of Long-Acting Injectable Cabotegravir Compared to Daily Oral TDF/FTC for Pre-Exposure Prophylaxis in HIV-Uninfected Women
This study will evaluate the safety and efficacy of the long-acting injectable agent cabotegravir (CAB LA) compared to daily oral tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) for pre
- 767 views
- 25 Jan, 2021
- 22 locations
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Multi-country trial
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Phase 1 trial
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Accepting adults
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10s of participants
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An interventional trial
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For females only
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Currently Recruiting
Pharmacokinetic Safety and Efficacy of B/F/TAF in HIV-1 Infected Virologically Suppressed Pregnant Women in Their Second and Third Trimesters
The primary objective of this study is to evaluate the steady state pharmacokinetics of bictegravir (BIC) and confirm the dose of BIC/emtricitabine/tenofovir alafenamide (B/F/TAF) 50/200/25 mg
- 60 views
- 13 Feb, 2021
- 19 locations
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Phase 4 trial
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Accepting adults
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1000s of participants
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An interventional trial
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For all genders
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Hepatology (Liver, Pancreatic, Gall Bladder)
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Currently Recruiting
A Real-World Study of Pegylated Interferon In Nucleoside-treated Patients With Chronic Hepatitis B
The aim of the prospective real-world study is to evaluate whether sequential combination therapy with pegylated interferon plus entecavir/tenofovir could induce higher rates of HBsAg loss in
- 41 views
- 22 Jan, 2021
- 10 locations
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Multi-country trial
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Phase 2 trial
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Accepting pediatric ages
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Accepting adults
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100s of participants
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An interventional trial
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For females only
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Pediatrics/Neonatology
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Currently Recruiting
Evaluating the Pharmacokinetics Feasibility Acceptability and Safety of Oral Pre-Exposure Prophylaxis for HIV Prevention During Pregnancy and Postpartum
The purpose of this study is to evaluate the pharmacokinetics, feasibility, acceptability, and safety of a fixed-dose combination of emtricitabine and tenofovir disoproxil fumarate (FTC/TDF) as
- 48 views
- 24 Jan, 2021
- 6 locations
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Multi-country trial
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Phase 2 trial
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Accepting pediatric ages
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Rheumatology
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Currently Recruiting
Study Evaluating Pharmacokinetics (PK) Safety and Efficacy of Cobicistat-boosted Atazanavir (ATV/co) or Cobicistat-boosted Darunavir (DRV/co) and Emtricitabine/Tenofovir Alafenamide (F/TAF) in HIV-1 Infected Virologically Suppressed Pediatric Participants
to < 12 years of age) To evaluate the steady-state PK of tenofovir alafenamide (TAF) and confirm the dose of emtricitabine/tenofovir alafenamide (F/TAF) in HIV-1 infected pediatric
- 236 views
- 28 Jan, 2021
- 37 locations
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Phase 4 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Hepatology (Liver, Pancreatic, Gall Bladder)
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Currently Recruiting
Effectiveness of TAF in Reducing Clinical Events in CHB Patients Beyond Treatment Indications by Current Guidelines
Treatment with Tenofovir Alafenamide(TAF) in Chronic Hepatitis B (CHB) patients classified as beyond treatment indication of current international guidelines (e.g. aged more than 40 years old
- 0 views
- 24 Jan, 2021
- 1 location
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Multi-country trial
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Phase 2 trial
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Accepting pediatric ages
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Currently Recruiting
A Study to Evaluate the Pharmacokinetics Safety Tolerability and Antiviral Activity of Rilpivirine (TMC278) in Human Immunodeficiency Virus Infected Adolescents and Children Aged Greater Than or Equal to 6 Years
investigator-selected background regimen containing 2 nucleoside/nucleotide reverse transcriptase inhibitors (N[t]RTIs) (zidovudine [AZT], abacavir [ABC], or tenofovir disoproxil fumarate [TDF] in combination
- 169 views
- 28 Jan, 2021
- 25 locations
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Multi-country trial
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Randomized Double-blind Efficacy and Safety Study of Doravirine/Islatravir (DOR/ISL) in Treatment-na ve Participants With Human Immunodeficiency Virus Type 1 (HIV-1) Infection (MK-8591A-020)
treatment-nave participants with human immunodeficiency virus type-1 (HIV-1) infection. The primary hypothesis is that DOR/ISL is non-inferior to bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF
- 4 views
- 03 Mar, 2021
- 35 locations