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Found 126 clinical trials
DORA: The Safety of Doravirine-based First-line Antiretroviral Therapy for Women of Reproductive Potential Living With HIV in South Africa

This is a pilot study investigating the safety of Doravirine (DOR) in combination with Lamivudine (3TC) and Tenofovir Disoproxil Fumarate (TDF) administered over 48 weeks in women of

  • 0 views
  • 26 Jan, 2021
  • 2 locations
Efficacy and Safety of TAF in Patients With Suboptimal Response to Other Nucleos(t)Ides

Both tenofovir disoproxil fumarate (TDF) and tenofovir alafenamide (TAF) are potent antiviral agents for hepatitis B virus (HBV) and recommended by the American Association for the Study of

lamivudine
tenofovir
liver disease
entecavir
adefovir
  • 0 views
  • 26 Jan, 2021
  • 10 locations
A Study to Evaluate the Efficacy and Safety of Therapeutic Hepatitis B Vaccine

The purpose of this study is to evaluate the evaluate and safety of the investigational medicinal product CVI-HBV-002.

antiviral drugs
tenofovir
chronic hepatitis
fumarate
hepatitis b antigen
  • 5 views
  • 24 Jan, 2021
  • 9 locations
Empiric Treatment for Acute HIV in the ED

An acceptance and feasibility study for immediate ART initiation and storage of laboratory specimens for individuals with suspected acute HIV infection who are diagnosed in one of the 7 participating emergency rooms

  • 0 views
  • 23 Jan, 2021
  • 1 location
IN-US-276-1340: Pre-Exposure Prophylaxis to Prevent HIV Acquisition in US Women: A Demonstration Project

The overall aim of this study is to assess attitudes toward PrEP, feasibility of Truvada PrEP procurement through the established access procedures, and adherence to Truvada PrEP among US women at risk for HIV acquisition.

  • 108 views
  • 28 Jan, 2021
  • 4 locations
HBV Vaccine in Anti-core Positive Donors After LT

Anti-HBc positive liver donors frequently have occult HBV infection, and several studies in HBsAg-negative subjects have shown that there is often the detection in the liver of covalently closed circular DNA (cccDNA). In the setting of liver transplantation and immunosuppresion, grafts from antiHBc positive donors may cause de novo HBV …

  • 0 views
  • 24 Jan, 2021
A Comparative Effectiveness Demonstration Project for Linkage and Retention in PrEP Care for Men Who Have Sex With Men

This research is being done to learn more about the differences in engaging, recruiting, linking and adhering to pre-exposure prophylaxis (PrEP) services for men who have sex with other men at risk for HIV in Baltimore City. In 2012, the U.S. Food and Drug Administration (FDA) approved the use of …

  • 66 views
  • 27 Jan, 2021
  • 1 location
Safety and Efficacy of Bictegravir/Emtricitabine/Tenofovir Alafenamide Versus Dolutegravir + Emtricitabine/Tenofovir Disoproxil Fumarate in Treatment Naive HIV-1 and Hepatitis B Co-Infected Adults

The primary objective of this study is to evaluate the efficacy of fixed-dose combination (FDC) of bictegravir/emtricitabine/ tenofovir alafenamide (B/F/TAF) versus dolutegravir (DTG

  • 459 views
  • 18 Feb, 2021
  • 122 locations
Tenofovir Alafenamide (TAF) in Children and Adolescents With Chronic Hepatitis B Virus Infection

The primary objective of Cohort 1 of this study is to evaluate the safety, tolerability, and antiviral activity (HBV DNA < 20 IU/mL) of tenofovir alafenamide (TAF) 25 mg once daily versus

antiviral drugs
estimated creatinine clearance
tenofovir
chronic hepatitis
hepatitis
  • 494 views
  • 04 Feb, 2021
  • 96 locations
A RCT of TNF and ENT in the Treatment of Long-term Prognosis With Hepatitis B-related HCC After Curative Resection

This study evaluates the addition of Tenofovir and Entecavir in the treatment of Hepatitis B-related hepatocellular carcinoma after curative resection in adults. Half of participants will

  • 0 views
  • 24 Jan, 2021
  • 1 location