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Found 194 clinical trials
Supramarginal Resection in Glioblastoma

population based cohorts being only 10 months. Extensive surgical resections followed by postoperative fractioned radiotherapy and concomitant and adjuvant temozolomide prolong survival and is the standard

astrocytoma
brain tumor
temozolomide
tumor cells
supratentorial glioblastoma multiforme
  • 0 views
  • 23 Jul, 2021
  • 19 locations
Pivotal Open-label Randomized Study of Radiosurgery With or Without Tumor Treating Fields (TTFields) for 1-10 Brain Metastases From Non-small Cell Lung Cancer (NSCLC).

The study is a prospective, randomized controlled phase III trial, to test the efficacy, safety and neurocognitive outcomes of advanced NSCLC patients, following stereotactic radiosurgery (SRS) for 1-10 brain metastases, treated with NovoTTF-100M compared to supportive treatment alone. The device is an experimental, portable, battery operated device for chronic administration …

  • 0 views
  • 15 Sep, 2021
  • 131 locations
Effect of Tumor Treating Fields (TTFields) (150 kHz) Concurrent With Standard of Care Therapies for Treatment of Stage 4 Non-small Cell Lung Cancer (NSCLC) Following Platinum Failure (LUNAR)

The study is a prospective, randomized controlled phase III trial aimed to test the efficacy and safety of TTFields, using the NovoTTF-100L System, concurrent with standard therapies for stage 4 NSCLC patients, following progression while on or after platinum based treatment.The device is an experimental, portable, battery operated device for …

systemic therapy
lung carcinoma
docetaxel
  • 644 views
  • 15 Sep, 2021
  • 179 locations
Effect of Tumor Treating Fields (TTFields 200 kHz) Concomitant With Weekly Paclitaxel for the Treatment of Recurrent Ovarian Cancer (ENGOT-ov50 / GOG-3029 / INNOVATE-3)

The study is a prospective, randomized controlled phase III trial aimed to test the efficacy and safety of Tumor Treating Fields (TTFields) concomitant with weekly paclitaxel for the treatment of recurrent ovarian cancer . The device is an experimental, portable, battery operated device for chronic administration of alternating electric fields …

paclitaxel
recurrent ovarian cancer
cancer of the ovary
carcinoma
fallopian tube
  • 276 views
  • 12 Sep, 2021
  • 141 locations
Effect of Tumor Treating Fields (TTFields 150 kHz) as Front-Line Treatment of Locally-advanced Pancreatic Adenocarcinoma Concomitant With Gemcitabine and Nab-paclitaxel (PANOVA-3)

Brief Summary: The study is a prospective, randomized controlled phase III trial aimed to test the efficacy and safety of Tumor Treating Fields (TTFields) in combination with gemcitabine and nab-paclitaxel, for front line treatment of locally-advanced pancreatic adenocarcinoma.The device is an experimental, portable, battery operated device for chronic administration of …

paclitaxel
gemcitabine
cancer
advanced pancreatic adenocarcinoma
metastasis
  • 232 views
  • 02 Sep, 2021
  • 188 locations
Temozolomide in Preventing Brain Metastases in Small Cell Lung Cancer

To investigate the response of temozolomide versus prophylactic cranial radiotherapy in preventing brain metastases in completed or partial remission limited small cell lung cancer patients.

  • 0 views
  • 23 Jan, 2021
  • 1 location
Neoadjuvant Temozolomide Combined With Simultaneous IMRT for Treatment of Glioblastoma

concurrent radiotherapy and chemotherapy, or neoadjuvant temozolomide combined with concurrent increased intensity-modulated radiotherapy. According to data from previous clinical trials, conventional doses

  • 0 views
  • 10 Apr, 2021
  • 1 location
Oral Capecitabine and Temozolomide (CAPTEM) for Newly Diagnosed GBM

The purpose of this study is to evaluate the safety and efficacy of administering the medication capecitabine along with temozolomide when you start your monthly regimen of oral temozolomide for

renal function test
renal function
temozolomide
glioblastoma multiforme
capecitabine
  • 78 views
  • 07 Sep, 2021
  • 1 location
Subventricular Zone (SVZ) and Temozolomide in Glioblastoma Multiforme

In this study patients will be treated with 6 weeks of radiation therapy plus temozolomide chemotherapy according to the standard of care. However, the radiation treatment plan will be modified

complete resection
temozolomide
gross total resection
  • 30 views
  • 26 Jan, 2021
  • 3 locations
TRC102 and Temozolomide for Relapsed Solid Tumors and Lymphomas

may allow chemotherapy to kill the cells more easily. Researchers want to see how well it works with temozolomide, a chemotherapy drug that is designed to damage tumor cell DNA. These drugs will be

temozolomide
tumor cells
blood transfusion
mitomycin
solid tumour
  • 11 views
  • 12 Sep, 2021
  • 1 location