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Found 9 clinical trials
PD1 Combined With Chemotherapy for Adjuvant Treatment of Gastric Cancer

"This is an international, multicenter, randomized, double-blind phase III study, plans to recruit 680 patients who received radical gastrectomy (R0, D2 or higher lymphadenectomy) with postoperative pathological stage II (T4aN0M0) or III (the 8th Edition American Joint Committee on Cancer [AJCC] Cancer Staging Manual) gastric adenocarcinoma and gastroesophageal junction adenocarcinoma, …

  • 4 views
  • 11 Aug, 2022
  • 25 locations
Neoadjuvant Immunochemotherapy in Locally Advanced Esophagogastric Junction Adenocarcinoma

The purpose of this study is to access the safety and efficacy of neoadjuvant Immunotherapy (Sintilimab, PD-1 inhibitor) combined with chemotherapy (Tegafur+Oxaliplatin) for locally advanced

  • 0 views
  • 08 Jan, 2022
  • 1 location
Adjuvant Chemotherapy in Combination With Camrelizumab for Stage III Gastric Cancer (FOCUS-02)

This study is a prospective, single arm, multi-center phase II clinical trial. The primary study objective is to evaluate the safety of tegafur gimeracil oteracil potassium capsule plus

  • 1 views
  • 21 Mar, 2022
  • 3 locations
The Combination Chemotherapy of SIRIOX as First- or Second-Line Chemotherapy for Pancreatic Cancer

Pancreatic cancer represents the most lethal of the common malignancies with a 5-year survival rate of less than 5%. For patients who are eligible for potentially curative resection, despite mortality and morbidity rates after surgery have improved, the recurrence rate is up to 85% within 2 years. FOLFIRINOX (fluoropyrimidine/leucovorin plus …

  • 16 views
  • 26 Feb, 2022
  • 2 locations
Study of Tislelizumab in Combination With SOX for the Treatment of Gastric Cancer With Liver Metastases

a clinical study of PD-1 monoclonal antibody (Tislelizumab) in combination with SOX (Tegafur + Oxaliplatin) for the treatment of liver metastases from gastric cancer. It aims to further explore a

  • 0 views
  • 05 May, 2022
  • 1 location
Study of Larotinib in Unresectable Advanced or Recurrent Esophageal Cancer

Hydrochloride Injection or Tegafur Gimeracil Oteracil Potassium Capsule),respecitively. Subjects are administered until disease progression assessed by the RECIST V1.1 standard (unless the investigator

esophagus cancer
recurrent esophageal cancer
irinotecan
squamous cell carcinoma
EGFR
  • 0 views
  • 17 Jul, 2021
  • 2 locations
A Study to Evaluate the Efficacy and Safety of Sintilimab Plus Apatinib and Chemotherapy in Patients With HER-2 Negative Microsatellite Stability (MSS) Advanced or Metastatic Gastric (GC) or Gastroesophageal Junction (GEJ) Cancer

To evaluate the efficacy and safety of Sintilimab combined with apatinib and chemotherapy as First-line or second-line Therapy in Treatment of HER-2 negative MSS Advanced or Metastatic GC or GEJ Cancer. At the same time, the correlation between tissue programmed death ligand-1(PD-L1) expression and blood circulating tumor cell(CTC) counts and …

immunostimulants
thromboplastin
apatinib
liver metastasis
chemotherapy regimen
  • 0 views
  • 19 Apr, 2022
  • 1 location
SOX-based CRT for Esophageal Cancer.

Patients with esophageal cancer that had locally advanced diseases or with unresectable diseases are being asked to participate in this phase I/II study. This phase I/II study is being conducted to determine the maximum-tolerated dose (MTD), dose-limiting toxicity (DLT), and efficacy of IMRT combined with S-1 and Oxaliplatin (SOX) based …

platelet count
neutrophil count
cancer
esophagus cancer
a hemoglobin
  • 11 views
  • 10 Feb, 2022
  • 1 location
  • 0 views
  • 10 Mar, 2022