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Found 103 clinical trials
Cannabinoids for Taxane Induced Peripheral Neuropathy

Taxane-induced peripheral neuropathy (TIPN) affects a significant number of women undergoing breast cancer treatment. Some patients may need to shorten their course of treatment, and do not

peripheral neuropathy
docetaxel
paclitaxel
cancer treatment
taxane
  • 0 views
  • 25 Jan, 2021
L-NMMA Plus Taxane Chemotherapy in Refractory Locally Advanced or Metastatic Triple Negative Breast Cancer Patients

This is a Phase Ib/II study assessing the maximum tolerated dose (MTD), dose-limiting toxicities (DLTs), recommended Phase 2 dose (RP2D), and efficacy of L-NMMA when combined with docetaxel in refractory locally advanced or metastatic triple negative breast cancer patients. The Phase Ib portion of the study is designed to investigate …

  • 45 views
  • 25 Jan, 2021
  • 1 location
Ipatasertib + Pertuzumab +Trastuzumab in Advanced HER2+ PI3KCA-mutant Breast Cancer Patients

taxane plus HP

invasive breast cancer
trastuzumab
breast adenocarcinoma
metastasis
breast cancer
  • 0 views
  • 24 Jan, 2021
  • 6 locations
NIAGEN and Persistent Chemotherapy-Induced Peripheral Neuropathy

neuropathy in cancer survivors who have completed chemotherapy with taxane or platinum-complex compounds between 1 and 12 months earlier.

peripheral neuropathy
estradiol
paclitaxel
ovarian cancer
taxane
  • 2 views
  • 25 Jan, 2021
  • 1 location
Everolimus (RAD001) and Carboplatin in Pretreated Metastatic Breast Cancer

taxane- and anthracycline-pretreated patients with progressive metastatic breast cancer. Additionally, the study is designed to characterize the safety, the tolerability and efficacy of this

stage iv breast cancer
taxane
carboplatin
anthracyclines
  • 22 views
  • 07 Nov, 2020
  • 1 location
GM1 in the Treatment of Neurotoxicity Induced by Albumin-bound Paclitaxel

Taxane-induced peripheral neuropathy (TIPN) caused by albumin-bound paclitaxel is a dose-limiting toxicity. The main symptoms of discomfort are numbness, tingling, and burning sensations in the

  • 0 views
  • 14 Jan, 2021
  • 1 location
A Study of Monosialic Gangliosides to Prevent Albumin-bound Paclitaxel Neurotoxicity

Taxane-induced peripheral neuropathy (TIPN) caused by paclitaxel is a dose-limiting toxicity. The main symptoms of discomfort are numbness, tingling, and burning sensations in the glove-sock

  • 0 views
  • 25 Jan, 2021
  • 1 location
Immunopheresis Alone or In Combination With Chemotherapy Versus Chemotherapy Alone in Advanced Triple Negative Breast Cancer (TNBC)

combination with a low dose weekly taxane (paclitaxel) plus carboplatin chemotherapy regimen. A weekly, combination of low dose paclitaxel plus carboplatin (paclitaxel+carboplatin) chemotherapy regimen will

  • 30 views
  • 18 Jan, 2021
  • 6 locations
Induction Paclitaxel Followed by Concurrent Paclitaxel and Radiation Therapy for Cutaneous Angiosarcoma

greater than 5 years. In other soft tissue sarcomas, the use of radiotherapy and/or chemotherapy have improved progression-free survival in patients undergoing limited, organ-sparing surgeries. Taxane

  • 0 views
  • 24 Jan, 2021
  • 1 location
Neoadjuvant Carboplatin in Triple Negative Breast Cancer

neoadjuvant chemotherapy based on anthracycline and taxane, with or without carboplatin.

  • 2 views
  • 23 Jan, 2021
  • 1 location