Found 68 clinical trials
Balloon vs. Self Expanding Transcatheter Valve for Degenerated Bioprosthesis (BASELINE)
Transcatheter aortic valve implantation (TAVI) serves a growing spectrum of patients with symptomatic severe aortic stenosis (AS). Approximately 80% of surgical aortic valve replacements is
- 1 views
- 04 Oct, 2022
- 4 locations
SAfe and Fast Discharge With Acurate Valve in Low Risk tavI Patients (SAFARI)
Recent evidence from scientific literature supported the extension of TAVI procedures to lower risk populations. Despite its widespread usage, the expansion of TAVI into lower risk patient
- 0 views
- 14 Aug, 2023
- 1 location
Effect of Antifibrotic Therapy on Regression of Myocardial Fibrosis After Transcatheter Aortic Valve Implantation (TAVI) in Aortic Stenosis Patients With High Fibrotic Burden (Reduce-MFA)
The aim of the study is to evaluate the effect of antifibrotic therapy on regression of myocardial fibrosis after TAVI in patients with baseline high fibrotic burden. Therefore, patients will be
- 0 views
- 12 Jul, 2022
- 1 location
A First-in-Human Study to Access Feasibility and Safety of the Optimum Aortic Valve Implant
The TAVI (Thubrikar Aortic Valve, Inc.) -1 Study: Safety and Performance Study of the Optimum Transcatheter Aortic Valve- First-in-human study to assess feasibility and safety of the Optimum
- 0 views
- 18 Oct, 2022
Comparison of Eligible TAVI-valves - Cohort B (Compare-TAVI)
The study performs head-to-head comparison of two TAVI-valves: Sapien and Myval.
- 0 views
- 04 Oct, 2022
- 1 location
Optimal Timing of Transcatheter Aortic Valve Implantation and Percutaneous Coronary Intervention - The TAVI PCI Trial
The primary objective of this study is to compare, in patients with severe aortic stenosis and concomitant coronary artery disease accepted for transcatheter aortic valve implantation (TAVI) and
- 0 views
- 15 Oct, 2021
- 1 location
Periprocedural Continuation Versus Interruption of Oral Anticoagulant Drugs During Transcatheter Aortic Valve Implantation (POPular PAUSE TAVI)
Transcatheter aortic valve implantation (TAVI) is a rapidly growing treatment option for patients with aortic valve stenosis. Stroke is a feared complication of TAVI, with an incidence of around
- 8 views
- 25 Oct, 2022
- 19 locations
Single Antiplatelet Treatment With Ticagrelor or Aspirin After Transcatheter Aortic Valve Implantation (REAC-TAVI2)
The optimal pharmacological therapy after transcatheter aortic valve implantation (TAVI) to prevent valve thrombosis and reduce thromboembolic complications without significantly increasing the
- 0 views
- 24 Apr, 2022
- 1 location
RHEIA (Randomized researcH in womEn All Comers With Aortic Stenosis) (RHEIA)
Purpose of this prospective, randomized, controlled, multi-center study is to evaluate the safety and efficacy of Transcatheter Aortic Valve Implantation (TAVI) as compared to surgical aortic
- 94 views
- 24 Mar, 2022
- 28 locations
Combined Transcatheter Aortic Valve Implantation and Percutaneous Closure of the Left Atrial Appendage (TAVI-LAAC)
Atrial fibrillation (AF) is a common comorbidity of patients candidates to transcatheter aortic valve implantation (TAVI). The management of chronic oral anticoagulation (OAC) for the prevention
- 0 views
- 22 Mar, 2022
- 4 locations