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Found 305 clinical trials
CCR2 PET for Pancreatic Cancer Imaging and Prediction of Response to Standard and CCR2-Targeted Therapy

Currently there is no clinical biomarker that can be used to select patients for CCR2-targeted therapy and to monitor response to such therapy. Considering the toxicity and the rate of response

paclitaxel
pdac
cancer
pancreaticoduodenectomy
gemcitabine
  • 0 views
  • 26 Jan, 2021
  • 1 location
CART Therapy in GUCY2C-positive Digestive Tract Tumors

Ict-gc is an open, single-center study to evaluate the safety and efficacy of CAR-T-targeted therapy in patients with advanced gastrointestinal tumors.

  • 0 views
  • 27 Jan, 2021
  • 1 location
  • 0 views
  • 05 Aug, 2021
  • 13 locations
Osimertinib In EGFR Mutant Lung Cancer

This research study is studying a targeted therapy as a possible treatment for Non-Small Cell Lung Cancer (NSCLC) with an EGFR mutation. The names of the study drug involved in this study

metastasis
secondary malignant neoplasm of liver
neutrophil count
targeted therapy
lung carcinoma
  • 3 views
  • 15 May, 2021
Regorafenib Plus Tislelizumab as First-line Systemic Therapy for Patients With Advanced Hepatocellular Carcinoma

Combination of anti-angiogenic molecular targeted therapy and anti- programmed cell death -1 immune checkpoint inhibitor (ICI) therapy has shown promising antitumor activity in multiple cancer

  • 0 views
  • 28 Jan, 2021
  • 1 location
Umbrella Study of Sasanlimab Combined With Targeted Therapies in Participants With Non Small Cell Lung Cancer

Phase 1b/Phase 2 open-label, multi-center, parallel group umbrella study. Sasanlimab (a PD-1 antagonist monoclonal antibody) will be combined with a different targeted therapy in each sub

cancer chemotherapy
lung carcinoma
measurable disease
  • 0 views
  • 05 Aug, 2021
  • 50 locations
  • 0 views
  • 26 Jan, 2021
  • 2 locations
Study of Biomarkers in Gynecological Cancers

cell changes is called "targeted therapy". Different people with the same type of cancer receiving the same drug could have different responses to it. For example, one person may experience a reduction

cancer
cancer care
  • 2 views
  • 22 Apr, 2021
  • 1 location
MEK and Autophagy Inhibition in Metastatic/Locally Advanced Unresectable Neuroblastoma RAS (NRAS) Melanoma

Patients with metastatic Neuroblastoma RAS (NRAS) melanoma are currently treated with first line immune checkpoint inhibitors (nivolumab, pembrolizumab). Thus far, no targeted therapy has been

  • 0 views
  • 25 Jan, 2021
  • 5 locations
Pyrotinib Maleate Combined With Vinorelbine in the Treatment of HER2-positive Advanced Breast Cancer

This study is a single-center, single-arm, prospective phase II clinical study, which mainly evaluates the efficacy and safety of pyrotinib maleate combined with oral vinorelbine in the treatment of HER2-positive advanced breast cancer.

  • 0 views
  • 04 Jun, 2021
  • 1 location