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Found 323 clinical trials
Safety and Efficacy of PD-1 Inhibitors in Patients With Liver Transplant

, or refractory after, locoregional therapy or to a curative treatment approach (eg, surgery, or ablation) and have previously been treated with sorafenib or other targeted therapy, either intolerant

cancer
hepatocellular carcinoma
metastases
arterial embolization
sorafenib
  • 4 views
  • 09 Feb, 2022
  • 1 location
Parametric PET of Genitourinary Cancer

Metastatic kidney cancer is usually treated with targeted therapy or immunotherapy which is costly and has low response rate. The current standard care is to perform anatomical imaging studies

cancer
everolimus
oophorectomy
pazopanib
clear cell renal cell carcinoma
  • 0 views
  • 18 Apr, 2021
  • 1 location
Niraparib and Dostarlimab for the Treatment of Small Cell Lung Cancer and Other High-Grade Neuroendocrine Carcinomas

targeted therapy. Immunotherapy with monoclonal antibodies, such as dostarlimab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread

cancer
systemic therapy
corticosteroids
neutrophil count
tumor cells
  • 0 views
  • 18 Oct, 2021
  • 1 location
NIH CCR2 AAA Study

this proposal is to develop a new approach for the diagnosis and targeted therapy of AAA.

  • 0 views
  • 08 Jul, 2021
  • 1 location
Prospective Study for the Application of Cytosorb in Critically Ill Patients

The mortality of critically ill patients is persistently high and requires targeted therapy of pathophysiological disorders. One approach to optimize therapy is the use of the cytokine adsorber

  • 0 views
  • 15 Jun, 2021
  • 1 location
Safety and Feasibility of Surgery After Conversion Therapy for Locally Advanced and Advanced NSCLC

Lung cancer is one of the most common malignant tumors worldwide and the mortality ranks first in the world. In recent years, with the development of targeted therapy and immunotherapy, the

lung carcinoma
cancer
lung cancer
  • 0 views
  • 05 Sep, 2021
  • 1 location
Testing Sacituzumab Govitecan Therapy in Patients With HER2-Negative Breast Cancer and Brain Metastases

monoclonal antibody, called sacituzumab, linked to a chemotherapy drug, called govitecan. Sacituzumab is a form of targeted therapy because it attaches to specific molecules on the surface of cancer cells

  • 0 views
  • 13 Mar, 2022
  • 105 locations
Tagraxofusp (SL-401) in Patients With CMML or MF

This multi-center, multi-arm trial is evaluating the safety and efficacy of tagraxofusp, a CD123-targeted therapy, in patients with either chronic myelomonocytic leukemia (CMML) or myelofibrosis

platelet count
dysplasia
chronic myelomonocytic leukemia
myelofibrosis
neutrophil count
  • 145 views
  • 10 May, 2022
  • 10 locations
Radiation Therapy With or Without Olaparib in Treating Patients With Inflammatory Breast Cancer

their damaged DNA, causing them to die. PARP inhibitors are a type of targeted therapy. It is not yet known whether radiation therapy with or without olaparib may work better in treating patients with

platelet count
estrogen receptor
mammogram
cyp3a inhibitors
skin cancer
  • 54 views
  • 16 May, 2022
  • 127 locations
The Rome Trial From Histology to Target: the Road to Personalize Target Therapy and Immunotherapy (ROME)

) of TT (targeted Therapy) vs SoC (standard of Care) in patients with progressive disease (recurrent and/or metastatic) of breast cancer, metastatic gastro-intestinal tumors, non small cell lung cancer

cancer
erlotinib
lapatinib
measurable disease
kidney function test
  • 101 views
  • 17 May, 2022
  • 38 locations