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Found 334 clinical trials
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Prophylaxis of Diarrhea in Adult Cancer Patients Receiving Targeted Cancer Therapy

A 24-week, (two 12-week stages), randomized, placebo-controlled, double-blind study to evaluate the safety and efficacy of crofelemer in providing prophylaxis of diarrhea in adult patients with solid tumors treated with targeted cancer therapy-containing treatment regimens. Diarrhea grading will be done according to the National Cancer Institute Common Terminology Criteria for …

  • 8 views
  • 15 Aug, 2021
  • 14 locations
None
Ultra Low Dose Radiation Delivered Before or After Chemotherapy-Free Targeted Therapy in Treating Patients With Relapsed or Refractory Mantle Cell Lymphoma

This phase II trial studies how well ultra low dose radiation works before or after chemotherapy-free targeted therapy in treating patients with mantle cell lymphoma that has come back or does

cancer
neutrophil count
leukemia
stem cell transplantation
ibrutinib
  • 5 views
  • 10 Oct, 2021
  • 1 location
None
SHIVA02 - Evaluation of the Efficacy of Targeted Therapy Based on Tumor Molecular Profiling in Patients With Advanced Cancer Using Each Patient as Its Own Control (SHIVA02)

The study will evaluate the efficacy of targeted therapy based on tumor molecular profiling versus conventional chemotherapy in patients with advanced cancer using each patient as its own

cancer
renal function test
metastatic malignant solid tumor
neutrophil count
solid tumour
  • 10 views
  • 03 Feb, 2021
  • 4 locations
None
A Study Using Regorafenib as Second or Third Line Therapy in Metastatic Medullary Thyroid Cancer

This research study is studying a targeted therapy as a possible treatment for thyroid cancer. A targeted therapy is a type of treatment that uses drugs or other substances to identify and

cancer
renal function
platelet count
neutrophil count
measurable disease
  • 11 views
  • 23 Sep, 2021
  • 2 locations
None
LY3214996 in Patients With AML Who Are Not Candidates for Standard Therapy

This research study is evaluating a targeted therapy as a possible treatment for acute myeloid leukemia (AML) that has returned or not responded to standard treatment.

cancer
refractory acute myeloid leukemia (aml)
direct bilirubin
  • 0 views
  • 22 Oct, 2021
None
Safety and Efficacy of Camrelizumab (Anti-PD-1 Antibody) in Recurrent HCC After Liver Transplantation

transplantation. All of the enrolled patients have a background of liver transplantation for HCC. Due to the tumor recurrence, patients are not suitable for curative surgical resection, and targeted therapy

sorafenib
metastases
metastasis
immune globulin
immunosuppression
  • 0 views
  • 25 Jan, 2021
  • 1 location
None
Micro-Ultrasound for the Detection and Localization of Prostate Cancer Tumors in Patients Undergoing Radical Prostatectomy

tissue around it). Usually multiparametric magnetic resonance imaging is used for the detection and targeted therapy of prostate cancer, but its accuracy remains imperfect. Micro-ultrasound may be

  • 0 views
  • 06 Nov, 2021
  • 1 location
None
A Study of Abemaciclib in Recurrent Glioblastoma

This research study is studying a targeted therapy as a possible treatment for recurrent glioblastoma (GBM). The following intervention will be used in this study: -Abemaciclib

low grade glioma
recurrent disease
karnofsky performance status
neutrophil count
tumor progression
  • 335 views
  • 11 Aug, 2021
  • 7 locations
None
A Study of Dabrafenib and/or Trametinib in Patients With Relapsed and/or Refractory Multiple Myeloma

This research study is studying a targeted therapy as a possible treatment for multiple myeloma. The names of the study drugs involved in this study are: Trametinib

line of therapy
kappa light chain
neutrophil count
monoclonal antibodies
calcium
  • 12 views
  • 08 Mar, 2021
  • 2 locations
None
  • 0 views
  • 08 Nov, 2020
  • 1 location