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Found 144 clinical trials
Featured trial
Co-Infusion of Umbilical Cord Blood and Haploidentical CD34+ Cells Following Nonmyeloablative Conditioning as Treatment for Severe Aplastic Anemia and MDS Associated with Severe Neutropenia Refractory to Immunosuppressive Therapy

irradiation to suppress immunity and prevent rejection of the donated cells. Infusion of the donated stem cells and umbilical cord cells. Immune suppression with the drugs tacrolimus

anemia
anemia studies
myelodysplastic syndromes
aplastic anemia
myelodysplastic syndrome (mds)
  • 54 views
  • 22 Dec, 2020
  • 1 location
Featured trial
A 3-week study to evaluate a generic non-steroidal topical cream for the treatment of eczema.

A 3-week study to evaluate a generic non-steroidal topical cream for the treatment of eczema.

  • 190 views
  • 08 Nov, 2020
  • 1 location
Featured trial
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of ABT-494 for Induction and Maintenance Therapy in Subjects With Moderately to Severely Active Ulcerative Colitis

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of ABT-494 for Induction and Maintenance Therapy in Subjects With Moderately to Severely Active Ulcerative Colitis

  • 290 views
  • 25 Mar, 2021
  • 1 location
Featured trial
A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of Investigational Product in Patients With Rheumatoid Arthritis (RA) With or Without Background Disease-Modifying Anti-rheumatic Drug (DMARD) Therapy

A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of Investigational Product in Patients With Rheumatoid Arthritis (RA) With or Without Background Disease-Modifying Anti-rheumatic Drug (DMARD) Therapy

  • 816 views
  • 08 Nov, 2020
  • 1 location
A Phase III Randomized, Open-Label Active Comparator-Controlled Multicenter Study to Evaluate Efficacy and Safety of Obinutuzumab in Patients With Primary Membranous Nephropathy

This study will evaluate the efficacy, safety, pharmacodynamics, and pharmacokinetics (PK) of obinutuzumab compared with tacrolimus in participants with primary membranous nephropathy (pMN).

  • 5 views
  • 20 Oct, 2022
  • 57 locations
Precision Guided Tacrolimus Dosing in Pediatric Heart Transplant

elimination of these agents. The goal of this research proposal is to clinically validate an innovative precision medicine strategy for dosing the immunosuppressant tacrolimus in pediatric heart transplant

  • 0 views
  • 19 Jun, 2022
  • 2 locations
Tacrolimus Formulation and Glucose Metabolism After Kidney Transplantation (TAGLUMET Trial) (TAGLUMET)

Posttransplantation diabetes mellitus after kidney transplantation mediated by tacrolimus is mainly dependent on dose and peak plasma concentration. To substantiate the potential benefits on

  • 0 views
  • 09 Jul, 2022
  • 1 location
Tacrolimus Versus Mycophenolate for Autoimmune Hepatitis Patients With Incomplete Response on First Line Therapy (TAILOR)

important risk factor for the need for liver transplantation or liver related death, independent of age and presence of cirrhosis. Tacrolimus (TAC) and mycophenolate mofetil (MMF) are frequently used to

  • 0 views
  • 22 Mar, 2022
  • 1 location
Viral Load Guided Immunosuppression After Lung Transplantation (VIGILung)

of Torque-Teno-Virus (TTV). The aim of the study is to investigate an individual adaptation of the calcineurin inhibitor tacrolimus (tailored calcineurin inhibitor dosing) by a non-invasive biomarker

  • 0 views
  • 10 Jul, 2022
  • 2 locations
  • 47 views
  • 28 Oct, 2022
  • 17 locations