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Found 35 clinical trials
Sacubitril/Valsartan Versus Valsartan in Heart Failure With Improved Ejection Fraction

Heart failure (HF) is a chronic disease with weakened heart muscles or abnormal pressure within the heart chambers result in breathlessness, leg edema, or fatigue. A subclass of HF shows reduced heart muscle contractility, which is represented by the left ventricular ejection fraction (LVEF). Valsartan is an angiotensin II receptor …

  • 0 views
  • 28 Aug, 2021
  • 1 location
Observational and Prospective Registry on Cardiac Contractility Modulation (CCM) Therapy

Observational and perspective study with acute and chronic endpoint.

  • 0 views
  • 11 Jun, 2021
  • 1 location
The Psoriasis Echo Study

In a prospective cohort study (n = 1.000), the investigators aim to investigate the correlation between cardiac biomarkers and advanced echocardiography and determine whether these are prognostic markers of heart disease in patients suffering from psoriasis.

heart disease
  • 0 views
  • 07 Oct, 2021
  • 1 location
Cardiac Output in Heart Failure Patients With Mechanical Pumps

This study will be looking at how cardiovascular hemodynamics, including cardiac output and flow through a left ventricular assist device (LVADs), change in response to alterations in preload, afterload, and contractility, and also during exercise, in humans with heart failure who are supported by LVADs.

  • 0 views
  • 21 Mar, 2022
  • 1 location
eMESH Struct. 2022-23 (eMESH)

A flexible energy metabolism matched with the contractile needs of the muscle is essential to a normal heart. Loss of metabolic flexibility and cardiac systolic efficiency coexist in Sepsis-induced Myocardial Dysfunction (SIMD), a phenomenon attributed to mitochondrial dysfunction and mishandling of energy substrates. Cardiac positron emission tomography (PET) could allow …

Accepts healthy volunteers
  • 0 views
  • 09 Aug, 2022
  • 1 location