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Found 35 clinical trials
Selective Cytopheretic Device (SCD) Trial

improve cardiovascular and renal function. The study will enroll eligible patients in the ICU with acute on chronic systolic heart failure and worsening renal function due to cardiorenal syndrome while

heart failure
systolic heart failure
inotropic agent
ejection fraction
angiotensin
  • 0 views
  • 20 Feb, 2022
  • 1 location
An Evaluation of the Safety and Performance of the Aortix System for Intra-Aortic Mechanical Circulatory Support in Patients With Cardiorenal Syndrome

The Aortix CRS Pilot Study: An Evaluation of the Safety and Performance of the Aortix System for Intra-Aortic Mechanical Circulatory Support in Patients with Cardiorenal Syndrome

edema
heart failure
decompensated heart failure
ejection fraction
chronic heart failure
  • 35 views
  • 15 Sep, 2022
  • 14 locations
Iron in Patients With Cardiovascular Disease (iCHF-2)

It is now recognized that iron deficiency in cardiovascular disease contributes to impaired clinical outcome.

transferrin
atrial fibrillation
infarction
transferrin saturation
myocardial infarction
  • 15 views
  • 10 Feb, 2022
  • 1 location
NAN-101 in Patients With Class III Heart Failure (NAN-CS101)

This is a Phase 1, prospective, multi-center, open-label, sequential dose escalation study to explore the safety, feasibility, and efficacy of a single intracoronary infusion of BNP116.sc-CMV.I1c in patients with NYHA Class III heart failure. Patients with symptomatic congestive heart failure will be enrolled until up to 12 subjects have received …

hysterectomy
angiotensin
cardiomyopathy
bilateral oophorectomy
congestive heart failure
  • 17 views
  • 19 Feb, 2022
  • 2 locations
Early Case Management on Recovery From a Cardiac Event in Women

Outpatient cardiac rehabilitation (CR) is an exercise-based lifestyle program for patients who have experienced a myocardial infarction, systolic heart failure, percutaneous revascularization or

  • 0 views
  • 06 Oct, 2021
  • 1 location
SCD for CRS in Congestive Heart Failure (CHF) (No Left Ventricular Assist Device)

The purpose of this clinical trial is to see if a new device (SCD) is safe and if it can reduce damage to the kidney enough to allow medications to work to improve heart and kidney function for use in patients that have moderate to severe heart failure and is …

edema
angiotensin
glomerular filtration rate
dyspnea
congestive heart failure
  • 0 views
  • 04 Oct, 2022
  • 1 location
High Calorie High Protein Nutrition Supplementation in Advanced Heart Failure

In this study, the investigators will determine the impact of a high calorie and high protein nutrition supplementation strategy on quality of life in participants with advanced heart failure. The investigators hypothesize that participants with advanced heart failure who receive the high calorie high protein nutrition supplementation strategy will experience …

heart failure
ejection fraction
  • 0 views
  • 04 Oct, 2022
  • 1 location
Angiotensin-Neprilysin Inhibition in Diastolic Dysfunction After AMI (ARNiAMI)

This study examines the effect of Entresto on central hemodynamic parameters during exercise in patients with diastolic dysfunction following acute myocardial infarction. Half of the patients will receive Entresto and the other half will receive placebo.

angiotensin
infarct
entresto
sacubitril
acute myocardial infarction
  • 0 views
  • 16 Feb, 2022
  • 1 location
CardiAMP™ Cell Therapy Heart Failure Trial

This is a prospective, multi-center, randomized (3 Treatment : 2 Sham Control), sham-controlled, patient- and evaluator-blinded study comparing treatment with the CardiAMP cell therapy to a sham treatment. A roll-in phase with a maximum of 10 subjects may occur.

myocardial infarction
ventriculogram
left ventricular dysfunction
ejection fraction
infarct
  • 14 views
  • 04 Oct, 2022
  • 24 locations
Lokelma for RAAS Maximisation in CKD & Heart Failure. (LIFT)

Background: CKD in patients with heart failure (HF) is common and associated with poor prognosis. Despite evidence of benefit with Renin-Angiotensin-Aldosterone-System inhibitor (RAASi) agents, they are avoided due to fear of hyperkalaemia. New potassium binders, e.g. Sodium Zirconium Cyclosilicate (SZC), reduce incidence of hyperkalaemia in CKD-HF patients and hence may …

heart failure
aldosterone
  • 0 views
  • 14 Mar, 2022