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Found 40 clinical trials
TransitionCHF Systolic Dysfunction to Congestive Heart Failure Cohort Study

TransitionCHF aims to recruit a unique cohort of patients with asymptomatic left ventricular dysfunction (NYHA I) to study the progression to symptomatic (>NYHA I) HF and to identify parameters/ biomarkers promoting and predicting the individual risk of transition. Results from TransitionCHF Cohort Study will inform and refine current treatment guidelines. …

  • 9 views
  • 21 Jan, 2021
Conduction System Pacing International Registry (CONSPIRE Registry)

The purpose of this registry study is to collect information about routine clinical practices with device implantation to treat bradycardia and cardiac systolic dysfunction (heart rhythm

systolic dysfunction
cardiac resynchronization therapy
  • 0 views
  • 18 Jun, 2022
  • 2 locations
Cohort of Patients With Left Ventricular Thrombus: Management and Outcomes in the Direct Oral Anticoagulants Era (LV-Thrombus)

The investigators' primary objective is to assess whether a difference in the occurrence of bleeding events exist between patients with LVT treated with DOACs as compared to those treated with VKAs.

  • 0 views
  • 26 May, 2022
  • 1 location
Thromboembolic and Bleeding Risk Stratification in Patients With Non-valvular Atrial Fibrillation (FASTRHAC)

The aim of the present prospective study is to further develop and validate a composite risk score predicting both ischemic and bleeding risk, based on epidemiologic, clinical, biological, and/or morphologic complementary data. First, the investigators will assess the predictive performance of current clinical risk scores. Second, the investigators will assess …

electrocardiogram
fibrillation
  • 6 views
  • 15 May, 2022
  • 2 locations
Role of Endomyocardial Biopsy and Aetiology-based Treatment in Patients With Inflammatory Heart Disease in Arrhythmic and Non-arrhythmic Clinical Presentations: an Integrated Approach for the Optimal Diagnostic and Therapeutic Management

Myocarditis is a complex inflammatory disease, usually occurring secondary to viral infections, autoimmune processes or toxic agents. Clinical presentations are multiple, including chest-pain, heart failure and a broad spectrum of arrhythmias. In turn, outcome is largely unpredictable, ranging from mild self-limiting disease, to chronic stage and progressive evolution towards dilated …

inflammatory disorder
myocarditis
MRI
ventricular arrhythmia
cardiomyopathy
  • 10 views
  • 24 Jan, 2021
  • 1 location
A Pilot Study of Cardiopulmonary Exercise Testing in Patients With Left Ventricular Systolic Dysfunction Receiving HER2-Targeted Therapy

The purpose of this study is to find out how much oxygen is used during a cardiopulmonary exercise test (CPET) in women who have mild cardiotoxicity after standard treatment for HER2-positive breast cancer, and to see whether the results of this test can be used to predict how well participants' …

erbb2
her2/neu-positive breast cancer
HER2
trastuzumab
pertuzumab
  • 0 views
  • 15 Oct, 2022
  • 1 location
eMESH Struct. 2022-23 (eMESH)

profiles. Comparisons will be performed between septic and acute on chronic heart failures, with or without systolic dysfunction.

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location
Bern Cardiac Amyloidosis REgistry (B-CARE) (B-CARE)

thickening, diastolic and systolic dysfunction to the development of terminal heart failure. Recently, treatment options for TTR amyloidosis have become available. However costs for therapy are enormous and

  • 0 views
  • 24 May, 2022
  • 1 location
Atherosclerosis in Chemotherapy-related Cardiotoxicity (ANTEC)

of atherosclerotic lesions in the coronary arteries assessed in computed tomography on the development of left ventricular systolic dysfunction in cancer patients at high risk of myocardial damage. A

diabetes
hmg-coa reductase inhibitor
cancer
heart failure
stroke
  • 0 views
  • 10 Mar, 2022
  • 1 location
GENETIC BASIS of LEFT VENTRICULAR APICAL HYPOPLASIA

Brief summary Left ventricular apical hypoplasia (LVAH) is a rare cardiomyopathy characterized by a spherical, truncated LV with some degree of systolic dysfunction, an elongated, normally

  • 0 views
  • 04 Mar, 2022
  • 1 location