Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 28 clinical trials
Featured trial
Pilot Study to Evaluate the Effect of Nicotinamide Riboside on Skeletal Muscle Function in Heart Failure Subjects

study how NR affects skeletal muscle function in people with heart failure. Eligibility: Adults ages 18-70 with clinically stable systolic heart failure

radionuclide ventriculography
cardiopulmonary exercise testing
systolic heart failure
chronic heart failure
heart failure
  • 311 views
  • 09 Apr, 2019
  • 1 location
Multi-lead ECG to Effectively Optimize Resynchronization Devices: New CRT Recipients (METEOR-CRT)

Cardiac resynchronization therapy (CRT), or atrial-synchronized biventricular (BiV) pacing, is an FDA-approved device therapy option for heart failure (HF) patients with reduced left ventricular ejection fraction and electrical dyssynchrony. A traditional CRT device has pacing leads implanted within the right atrium (RA), the right ventricle (RV), and within a coronary …

medical therapy
ejection fraction
cardiac resynchronization therapy
  • 0 views
  • 14 Jun, 2022
  • 2 locations
Multi-intravenous Infusion of Umbilical Cord Mesenchymal Stem Cells in Heart Failure With Reduced Ejection Fraction PRIME-HFrEF Study

This study is an exploratory clinical study to observe the safety and efficacy of the Intravenous Infusion of Umbilical Cord Mesenchymal Stem Cells in the heart failure patients with reduced ejection fraction. The study was a 12 months single center, randomized, double-blind, placebo-controlled trial that included 12 weeks of treatment, …

  • 0 views
  • 24 Nov, 2021
  • 1 location
Effects of CRT Optimization as Assessed by Cardiac MR

Cardiac resynchronization therapy (CRT), or atrial-synchronized biventricular (BiV) pacing, is an FDA-approved device therapy option for heart failure (HF) patients with reduced left ventricular ejection fraction and electrical dyssynchrony. A traditional CRT device has pacing leads implanted within the right atrium (RA), the right ventricle (RV), and within a coronary …

  • 0 views
  • 04 Oct, 2021
  • 2 locations
Mechanistic Clinical Trial of Advanced Imaging for CRT

This is a mechanistic clinical trial with randomization to guidance for the CRT procedure using cardiac magnetic resonance (CMR) and computed tomography angiography (CTA) versus a standard procedure.

MRI
angiography
  • 7 views
  • 26 Feb, 2022
  • 1 location
Intravenous Iron in Patients With Systolic Heart Failure and Iron Deficiency to Improve Morbidity & Mortality (FAIR-HF2)

The purpose of this study is to determine whether intravenous iron supplementation using ferric carboxymaltosis (FCM) reduces hospitalisation and mortality in patients with iron deficiency and heart failure.

malnutrition
iron
iron deficiency anemia
systolic heart failure
chronic heart failure
  • 13 views
  • 24 Feb, 2022
  • 32 locations
RCT of Implantable Defibrillators in Patients With Non Ischemic Cardiomyopathy, Scar and Severe Systolic Heart Failure (BRITISH)

BRITISH is a UK multicentre trial of patients who have been diagnosed with heart failure due to Non-Ischemic Cardiomyopathy (NICM, or heart failure that is not caused by blocked heart arteries. Participants will be randomised into two groups. Half the participants will receive an Implantable Cardioverter-Defibrillator (ICD) and the other …

  • 0 views
  • 12 Aug, 2023
  • 15 locations
The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial

The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy (STICH3C) trial is a prospective, unblinded, international multi-center randomized trial of 754 subjects enrolled in approximately 45 centers comparing revascularization by percutaneous coronary intervention (PCI) vs. coronary artery bypass grafting (CABG) in patients with multivessel/left main (LM) coronary artery disease …

  • 0 views
  • 13 Aug, 2023
  • 4 locations
Cryoballoon Ablation Versus Medical Therapy in Patients With Heart Failure and Atrial Fibrillation

Rationale Atrial fibrillation (AF) and heart failure (HF) can cause each other and sustain each other. Combined, the two diseases negatively influence each other's prognosis and lead to higher mortality. Studies in HF patients in which the AF burden is reduced by AF ablation show promising results toward improved prognosis, …

  • 0 views
  • 24 Mar, 2021
  • 2 locations
Effect of Music on Cardiopulmonary Exercise Capacity in Heart Failure Patients (MUSIC-CPX)

The study aims to assess the effect of music on the heart resulting in a change in their exercise capacity among systolic heart failure patients undergoing Cardiopulmonary Exercise testing.

heart failure
systolic heart failure
  • 0 views
  • 20 Aug, 2023
  • 1 location